Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04GKL
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| Former ID |
DIB007588
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| Drug Name |
RAXOFELAST
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| Synonyms |
IRFI-016; Raxofelast; Rac-2-(5-Acetoxy-4,6,7-trimethyl-2,3-dihydrobenzofuran-2-yl)acetic acid
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| Drug Type |
Small molecular drug
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| Indication | Ischemia [ICD-11: 8B10-8B11; ICD-9: 459.89] | Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H18O5
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| Canonical SMILES |
CC1=C(C(=C(C2=C1OC(C2)CC(=O)O)C)OC(=O)C)C
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| InChI |
1S/C15H18O5/c1-7-8(2)15-12(5-11(20-15)6-13(17)18)9(3)14(7)19-10(4)16/h11H,5-6H2,1-4H3,(H,17,18)
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| InChIKey |
QLWBKUUORSULMI-UHFFFAOYSA-N
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| CAS Number |
CAS 128232-14-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Lipid peroxidation (LPO) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001571) | |||
| REF 2 | Lipid peroxidation inhibition by raxofelast improves angiogenesis and wound healing in experimental burn wounds. Shock. 2005 Jul;24(1):85-91. | |||
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