Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0R0OC
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| Former ID |
DIB008772
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| Drug Name |
U-104067F
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| Synonyms |
U-104067 (anhydrous free base); 9-[2-(4-Morpholinyl)ethyl]-2,4-bis(pyrrolidin-1-yl]-9H-pyrimido[4,5-b]indole monohydrochloride hemihydrate
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| Drug Type |
Small molecular drug
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| Indication | Neurological disorder [ICD-11: 6B60] | Discontinued in Phase 1 | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C24H33ClN6O
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| Canonical SMILES |
C1CCN(C1)C2=NC(=NC3=C2C4=CC=CC=C4N3CCN5CCOCC5)N6CCCC6.Cl
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| InChI |
1S/C24H32N6O.ClH/c1-2-8-20-19(7-1)21-22(28-9-3-4-10-28)25-24(29-11-5-6-12-29)26-23(21)30(20)14-13-27-15-17-31-18-16-27;/h1-2,7-8H,3-6,9-18H2;1H
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| InChIKey |
OTTSSGXCAVAVKV-UHFFFAOYSA-N
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| CAS Number |
CAS 172035-75-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Lipid peroxidation (LPO) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006788) | |||
| REF 2 | Two novel pyrrolopyrimidine lipid peroxidation inhibitors U-101033E and U-104067F protect facial motor neurons following neonatal axotomy. Exp Neurol. 1996 Oct;141(2):304-9. | |||
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