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Target and Pathway |
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Target(s) |
DNA-dependent protein kinase catalytic (PRKDC) |
Target Info
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Inhibitor |
[1] |
Serine/threonine-protein kinase mTOR (mTOR) |
Target Info
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Inhibitor |
[2] |
References |
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REF 1 |
Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6083-7.
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REF 2 |
Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and... J Med Chem. 2005 Jan 27;48(2):569-85.
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