Drug Information

Target and Pathway

Target(s)

Nicotinamide phosphoribosyltransferase (NAMPT)

Target Info

Inhibitor

[1], [2]

References

REF 1

Anticancer agent CHS-828 inhibits cellular synthesis of NAD. Biochem Biophys Res Commun. 2008 Mar 21;367(4):799-804.

REF 2

Structural basis for resistance to diverse classes of NAMPT inhibitors. PLoS One. 2014 Oct 6;9(10):e109366.

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