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Target and Pathway |
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Target(s) |
Steroid 11-beta-hydroxylase (CYP11B1) |
Target Info
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Inhibitor |
[1] |
Steroid 17-alpha-monooxygenase (S17AH) |
Target Info
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Inhibitor |
[1] |
References |
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REF 1 |
Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prosta... J Med Chem. 2010 Aug 12;53(15):5749-58.
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