| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T34287 | ||||
| Target Name | Candida Mannose-6-phosphate isomerase (Candi PMI1) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | Drug Info | IC50 = 3550 nM | [1] | ||
| GNF-PF-2272 | Drug Info | IC50 = 6088 nM | [1] | ||
| GNF-PF-5134 | Drug Info | IC50 = 13733 nM | [1] | ||
| References | |||||
| REF 1 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. | ||||
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