Drug Information

Drug General Information
Drug ID
D00WPU
Former ID
DIB013481
Drug Name
Sazetidine-A
Synonyms
Sazetidine-A; AMOP-H-OH; Nicotinic ligands (depression, pain, nicotine dependence); Nicotinic ligands (depression, pain, nicotine dependence), PsychoGenics
Drug Type
Small molecular drug
Indication Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10:F32, F33, M32] Investigative [532808]
Company
University of Illinois
Structure
Download
2D MOL

3D MOL
Formula
C15H20N2O2
Canonical SMILES
c1ncc(cc1OCC1CCN1)C#CCCCCO
PubChem Compound ID
11983356
Target and Pathway
Target(s) Nicotinic acid receptor 1 Target Info Binder [532808]
KEGG Pathway cAMP signaling pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
References
Ref 532808Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. ACS Med Chem Lett. 2011 Nov 24;3(1):63-8.
Ref 532808Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. ACS Med Chem Lett. 2011 Nov 24;3(1):63-8.

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