Drug Information

Drug General Information
Drug ID
D06WXN
Former ID
DIB019610
Drug Name
compound 8f
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531020], [541112]
Structure
Download
2D MOL
Formula
C11H12N4O2
InChI
InChI=1S/C11H12N4O2/c1-15-9(2-3-12-15)6-4-7-8(5-6)13-14-10(7)11(16)17/h2-3,6H,4-5H2,1H3,(H,13,14)(H,16,17)
InChIKey
ZAJBYTSUTBCMRM-UHFFFAOYSA-N
PubChem Compound ID
12003694
PubChem Substance ID
17502944, 36496004, 77754849, 99371989, 104237113, 117644719, 137396462, 178102418, 238924168, 242948294
Target and Pathway
Target(s) Nicotinic acid receptor 1 Target Info Agonist [531020]
KEGG Pathway cAMP signaling pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
References
Ref 531020Bioorg Med Chem Lett. 2010 Aug 1;20(15):4472-4. Epub 2010 Jun 10.GPR109a agonists. Part 2: pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a.
Ref 541112(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5793).
Ref 531020Bioorg Med Chem Lett. 2010 Aug 1;20(15):4472-4. Epub 2010 Jun 10.GPR109a agonists. Part 2: pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a.

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