Drug Information

Drug General Information
Drug ID
D07TVE
Former ID
DIB019159
Drug Name
compound (+)17a
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530828], [541110]
Structure
Download
2D MOL
Formula
C8H8N6
InChI
InChI=1S/C8H8N6/c1-3-2-5-6(4(1)3)9-10-7(5)8-11-13-14-12-8/h3-4H,1-2H2,(H,9,10)(H,11,12,13,14)
InChIKey
DKSPRNJUDCWTID-UHFFFAOYSA-N
PubChem Compound ID
11672811
PubChem Substance ID
16776663, 78242868, 99289738, 103770286, 104153254, 139755652, 178102415, 230408064, 237714372, 242996185, 247291252
Target and Pathway
Target(s) Nicotinic acid receptor 1 Target Info Agonist [530828]
KEGG Pathway cAMP signaling pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
References
Ref 530828Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a). Bioorg Med Chem Lett. 2010 May 1;20(9):2797-800.
Ref 541110(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5790).
Ref 530828Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a). Bioorg Med Chem Lett. 2010 May 1;20(9):2797-800.

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