Drug Information

Drug General Information
Drug ID
D0V4GY
Former ID
DAP001326
Drug Name
Chlorhexidine
Synonyms
AVAGARD; Chlorhexidin; Chlorhexidinum; Cloresidina; Clorhexidina; Fimeil; Hexadol; Hibiclens; Hibispray; Hibistat;Nolvasan; Novalsan; Peridex; Periogard; Rotersept; Savloclens; Soretol; Sterido; Sterilon; Superspray; Tubulicid; Chlorhexidin [Czech]; Chlorhexidine Base; Chlorhexidine gluconate; Cloresidina [DCIT]; Decanoylacetaldehyde Sodium Sulfide; Dentisept [veterinary]; Savlon babycare; Sebidin A; Sodium Houttuyfonamide; Avagard (TN); BIOPATCH (TN); ChloraPrep (TN); Chlorhexamed (TN); Chlorhexidine (INN);Chlorhexidine [INN:BAN]; Chlorhexidinum [INN-Latin]; Chlorohex (TN); Clohex (TN); Clorexil (TN); Clorhexidina [INN-Spanish]; Corsodyl (TN); Dentisept [veterinary] (TN); Dexidin (TN); Exidine (TN); Hibiclens (TN); Hibiscrub (TN); MK-412A; Merfen-incolore; Oro-Clense; Oronine (TN); Perichlor (TN); Peridex (TN); Peridont (TN); Periochip (TN); Periogard Oral Rinse (TN); Perioxidina (TN); Savacol (TN); Suthol (TN); Dejavu-MW (TN); Merfen-incolore (TN); Lisium (*Dihydrochloride*); Nolvasan (*Diacetate*); SOLU-I.V (TN); N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide; N,N''''-hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)]; N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradeca-nediimidamide; N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)]; 1,1 inverted exclamation marka-Hexamethylenebis[5-(4-chlorophenyl)biguanide]; 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide); 1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide); 1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide; 1,6-Bis(5-(p-chlorophenyl)biguandino)hexane; 1,6-Bis(p-chlorophenyldiguanido)hexane; 1,6-Di(4'-chlorophenyldiguanido)hexane; 1,6-Di(N-p-chlorophenyldiguanido)hexane
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [538533]
Therapeutic Class
Antibiotics
Company
G. D. Pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C22H30Cl2N10
Canonical SMILES
C1=CC(=CC=C1NC(=NC(=NCCCCCCN=C(N)N=C(N)NC2=CC=C(C=C2)Cl<br />)N)N)Cl
InChI
1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34)
InChIKey
GHXZTYHSJHQHIJ-UHFFFAOYSA-N
CAS Number
CAS 55-56-1
PubChem Compound ID
9552079
PubChem Substance ID
9119, 600474, 10321154, 11112130, 11335936, 11361175, 11363131, 11365693, 11368255, 11371297, 11373913, 11376417, 11462147, 11466171, 11467291, 11483946, 11485921, 11487951, 11490155, 11492092, 11494051, 14884555, 17389113, 24712465, 24854905, 24857031, 24861545, 25675207, 26752881, 46506388, 47291166, 47365220, 47589027, 47662313, 47885444, 47959776, 48110471, 48185027, 48424952, 49698845, 49893853, 51091970, 56324225, 56324718, 56463343, 57372731, 57737486, 78205044, 81041550, 85174368
ChEBI ID
ChEBI:3614
SuperDrug ATC ID
A01AB03; B05CA02; D08AC02; D09AA12; R02AA05; S01AX09; S02AA09; S03AA04
SuperDrug CAS ID
cas=000055561
Target and Pathway
Target(s) Dihydropteroate synthetase Target Info Breaker [535808]
References
Ref 538533FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019822.
Ref 535808The mechanism of action of chlorhexidine. FEMS Microbiol Lett. 1992 Dec 15;79(1-3):211-5.

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