Drug General Information
Drug ID
D0R4GX
Former ID
DIB018963
Drug Name
beta-D-hydroxybutyric acid
Synonyms
3-hydroxybutyrate; (R)-3-hydroxybutanoate
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538971]
Structure
Download
2D MOL
Formula
C4H8O3
InChI
InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m1/s1
InChIKey
WHBMMWSBFZVSSR-GSVOUGTGSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Nicotinic acid receptor 1 Target Info Agonist [527576]
KEGG Pathway cAMP signaling pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
References
Ref 538971(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1593).
Ref 527576(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. J Biol Chem. 2005 Jul 22;280(29):26649-52. Epub 2005 Jun 1.

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