Drug General Information
Drug ID	D0S3XI
Former ID	DIB020389
Drug Name	monomethylfumarate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541105]
Structure		Download 2D MOL 3D MOL
Formula	C5H6O4
InChI	InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+
InChIKey	NKHAVTQWNUWKEO-NSCUHMNNSA-N
PubChem Compound ID	5369209
PubChem Substance ID	11656144, 14747649, 24883828, 39389755, 57362341, 79686239, 85245433, 90417319, 103724331, 114166309, 117544853, 118313549, 126551303, 131345362, 135060089, 136992887, 137202212, 137251158, 142653492, 143438467, 144107207, 152032061, 162077181, 162183081, 163413037, 164811949, 164841619, 172892108, 175267099, 178102411, 204371895, 223349343, 223560257, 224361589, 226442098, 226442099, 241058095, 244277959, 248094066, 249848971, 249965991, 252035329, 252158126, 252410803
Target and Pathway
Target(s)	Nicotinic acid receptor 1	Target Info	Agonist	[529650]
KEGG Pathway	cAMP signaling pathway
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (i) signalling events
WikiPathways	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541105	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5786).
Ref 529650	The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist. Biochem Biophys Res Commun. 2008 Oct 31;375(4):562-5.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.