Target Validation Information | |||||
---|---|---|---|---|---|
Target ID | T43332 | ||||
Target Name | Coagulation factor VII | ||||
Target Type | Successful |
||||
Drug Potency against Target | 4-(3,4-Diethoxy-benzylamino)-benzamidine | Drug Info | Ki = 4200 nM | [527397] | |
4-(4-Benzyloxy-3-methoxy-benzylamino)-benzamidine | Drug Info | Ki = 1000 nM | [527397] | ||
References | |||||
Ref 527397 | Bioorg Med Chem Lett. 2005 Feb 1;15(3):817-22.Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors. | ||||
Ref 527397 | Bioorg Med Chem Lett. 2005 Feb 1;15(3):817-22.Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors. |
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