TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T03634 CREB-binding protein B30YQB (4s)-4-Methyl-1,3,4,5-tetrahydro-2h-1,5-benzodiazepin-2-one Investigative 735746 C10H12N2O 176.21 C[C@H]1CC(=O)NC2=CC=CC=C2N1 IC50 > 2000000 nM Non binder T03634 CREB-binding protein B74AOB 3-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one Investigative 3152392 C10H12N2O 176.21 CC1CNC2=CC=CC=C2NC1=O IC50 > 200000 nM Non binder T03634 CREB-binding protein B9RNU5 3,5 Dimethyl-4-Phenyl-1,2-Oxazole Investigative 5325760 C11H11NO 173.21 CC1=C(C(=NO1)C)C2=CC=CC=C2 IC50 > 200000 nM Non binder T03634 CREB-binding protein B9V3YB 1,3,4,5-Tetrahydro-2H-1,5-benzodiazepin-2-one Investigative 223771 C9H10N2O 162.19 C1CNC2=CC=CC=C2NC1=O IC50 > 200000 nM Non binder T03634 CREB-binding protein BC5PQ4 Methyl 2-oxo-2,3-dihydro-1,3-benzoxazole-6-carboxylate Investigative 12564532 C9H7NO4 193.16 COC(=O)C1=CC2=C(C=C1)NC(=O)O2 IC50 = 455000 nM Non binder T03634 CREB-binding protein BE20AH Butyrolactone 3 Investigative 10081070 C9H12O4 184.19 CCC[C@H]1[C@@H](C(=C)C(=O)O1)C(=O)O IC50 = 500000 nM Non binder T03634 CREB-binding protein BIH2X9 (2R,3R)-4-Methylidene-5-oxo-3-propyloxolane-2-carboxylic acid Investigative 127032947 C9H12O4 184.19 CCC[C@H]1[C@@H](OC(=O)C1=C)C(=O)O IC50 = 500000 nM Non binder T03634 CREB-binding protein BLON04 3-Methyl-3,4-dihydro-1H-quinoxalin-2-one Investigative 2763642 C9H10N2O 162.19 CC1C(=O)NC2=CC=CC=C2N1 IC50 = 1900000 nM Non binder T03634 CREB-binding protein BRZX96 4,4-Dimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one Investigative 12206142 C11H14N2O 190.24 CC1(CC(=O)NC2=CC=CC=C2N1)C IC50 > 200000 nM Non binder T03634 CREB-binding protein BTZM15 2-[5-(3,5-Dimethyl-1,2-oxazol-4-yl)-2-(2-phenylethyl)benzimidazol-1-yl]-N,N-dimethylethanamine Investigative 127035170 C24H28N4O 388.5 CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)CCC4=CC=CC=C4)CCN(C)C IC50 = 500000 nM Non binder T03634 CREB-binding protein BYVF35 1-Methyl-2-pyrrolidinone Investigative 13387 C5H9NO 99.13 CN1CCCC1=O IC50 = 2300000 nM Non binder