TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T31391	Dipeptidyl peptidase 4	D08PUW	BAICALIN	Terminated	64982	C21H18O11	446.4	C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O	IC50 = 225000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B01DZW	Isoindolin-2-yl((2S,4R)-4-(naphthalen-2-ylamino)pyrrolidin-2-yl)methanone	Investigative	44560750	C23H23N3O	357.4	C1[C@H](CN[C@@H]1C(=O)N2CC3=CC=CC=C3C2)NC4=CC5=CC=CC=C5C=C4	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B0B6YP	2,6-Diamino-1-thiazolidin-3-yl-hexan-1-one	Investigative	44364298	C9H19N3OS	217.33	C1CSCN1C(=O)C(CCCCN)N	IC50 = 318000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B0RX3J	(2S,4S)-4-(4-Chlorobenzylamino)-2-amino-1-(piperidin-1-yl)pentan-1-one	Investigative	16046127	C17H26ClN3O	323.9	C[C@@H](C[C@@H](C(=O)N1CCCCC1)N)NCC2=CC=C(C=C2)Cl	IC50 = 325000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B0Z3JL	2-(S)-Amino-4-(3-methoxy-benzylamino)-1-piperidin-1-yl-butan-1-one	Investigative	11220471	C17H27N3O2	305.4	COC1=CC=CC(=C1)CNCC[C@@H](C(=O)N2CCCCC2)N	IC50 = 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B15SMO	(R)-1-(4-Oxo-4-phenylbutanoyl)pyrrolidin-2-ylboronic acid	Investigative	44418253	C14H18BNO4	275.11	B([C@@H]1CCCN1C(=O)CCC(=O)C2=CC=CC=C2)(O)O	Ki = 451000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B16KXF	(S)-2-Amino-1-(pyrrolidine-1-yl)-3-(1H-indole-3-yl)propane-1-one	Investigative	10780092	C15H19N3O	257.329	C1CCN(C1)C(=O)[C@H](CC2=CNC3=CC=CC=C32)N	IC50 = 286000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B2BF5P	2-Amino-1-piperidin-1-yl-butan-1-one	Investigative	12742483	C9H18N2O	170.25	CCC(C(=O)N1CCCCC1)N	IC50 = 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B2HG8W	2,6-Diamino-1-(3,6-dihydro-2H-pyridin-1-yl)-hexan-1-one	Investigative	44364231	C11H21N3O	211.3	C1CN(CC=C1)C(=O)C(CCCCN)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B2N3MR	2,6-Diamino-1-azetidin-1-yl-hexan-1-one	Investigative	44364211	C9H19N3O	185.27	C1CN(C1)C(=O)C(CCCCN)N	IC50 = 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B2NSL8	Fluoro-Olefin Analogue 10	Investigative	23646089	C18H28FN	277.4	C1CCC(=C(CNC23CC4CC(C2)CC(C4)C3)F)CC1	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B2P5LC	(2S)-2,6-Diamino-1-(3-hydroxypyrrolidin-1-yl)hexan-1-one	Investigative	11310450	C10H21N3O2	215.29	C1CN(CC1O)C(=O)[C@H](CCCCN)N	IC50 = 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B2X8FJ	(S)-2-Amino-4-(4-chloro-benzylamino)-1-(2-methyl-piperidin-1-yl)-butan-1-one	Investigative	11359214	C17H26ClN3O	323.9	CC1CCCCN1C(=O)[C@H](CCNCC2=CC=C(C=C2)Cl)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B38GKD	(2H-1,3-Benzodioxol-5-ylmethyl)(2-cyclopentylideneethyl)amine	Investigative	11207320	C15H19NO2	245.32	C1CCC(=CCNCC2=CC3=C(C=C2)OCO3)C1	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B39QDU	N-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butyl)-acetamide	Investigative	10353699	C11H21N3O2	227.3	CC(=O)NCC[C@@H](C(=O)N1CCCCC1)N	IC50 = 518000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B3DCW5	2-(S)-Amino-4-(3-phenyl-propylamino)-1-piperidin-1-yl-butan-1-one	Investigative	11312733	C18H29N3O	303.4	C1CCN(CC1)C(=O)[C@H](CCNCCCC2=CC=CC=C2)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B3E1DF	1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-	Investigative	1235479	C20H22N2O2	322.4	CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=O)C3=C(C2=O)C=C(C=C3)N	IC50 = 251200 nM	Non binder
T31391	Dipeptidyl peptidase 4	B3F0TL	2-Amino-1-piperidin-1-yl-hexan-1-one	Investigative	44364102	C11H22N2O	198.31	CCCCC(C(=O)N1CCCCC1)N	IC50 = 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B3REA8	2-Amino-1-azepan-1-yl-3-methyl-pentan-1-one	Investigative	24704198	C12H24N2O	212.33	CCC(C)C(C(=O)N1CCCCCC1)N	IC50 = 374000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B3RLF8	(S)-2-Amino-4-phenylamino-1-piperidin-1-yl-butan-1-one	Investigative	11436930	C15H23N3O	261.36	C1CCN(CC1)C(=O)[C@H](CCNC2=CC=CC=C2)N	IC50 = 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B57KRT	4-Hydroxy-2-(2-methylsulfanyl-phenyl)-isoindole-1,3-dione	Investigative	44368725	C15H11NO3S	285.3	CSC1=CC=CC=C1N2C(=O)C3=C(C2=O)C(=CC=C3)O	IC50 = 225700 nM	Non binder
T31391	Dipeptidyl peptidase 4	B5WSV7	2-(2,6-Dimethylphenyl)-4-nitro-1H-isoindole-1,3(2H)-dione	Investigative	721814	C16H12N2O4	296.28	CC1=C(C(=CC=C1)C)N2C(=O)C3=C(C2=O)C(=CC=C3)[N+](=O)[O-]	IC50 > 337500 nM	Non binder
T31391	Dipeptidyl peptidase 4	B67IAM	Fluoro-Olefin Analogue 9	Investigative	23646088	C14H24FN	225.35	C1CCC(CC1)NCC(=C2CCCCC2)F	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B69EXM	(2S,4R)-4-(4-Chlorobenzylamino)-2-amino-5-methyl-1-(piperidin-1-yl)heptan-1-one	Investigative	44415929	C20H32ClN3O	365.9	CCC(C)[C@@H](C[C@@H](C(=O)N1CCCCC1)N)NCC2=CC=C(C=C2)Cl	IC50 = 234000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B6F0CW	Benzyl N-[(2S)-6-amino-1-[1-bis(4-acetamidophenoxy)phosphoryl-1,3-dihydroisoindol-2-yl]-1-oxohexan-2-yl]carbamate	Investigative	44435316	C38H42N5O8P	727.7	CC(=O)NC1=CC=C(C=C1)OP(=O)(C2C3=CC=CC=C3CN2C(=O)[C@H](CCCCN)NC(=O)OCC4=CC=CC=C4)OC5=CC=C(C=C5)NC(=O)C	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B6FG7V	1-(Aminomethyl)-6,7-dimethoxyisoquinoline-4-carbaldehyde;hydrochloride	Investigative	45259892	C13H15ClN2O3	282.72	COC1=C(C=C2C(=C1)C(=CN=C2CN)C=O)OC.Cl	IC50 = 277000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B6QYR2	2-(2,6-Dimethyl-phenyl)-4-hydroxy-isoindole-1,3-dione	Investigative	10492044	C16H13NO3	267.28	CC1=C(C(=CC=C1)C)N2C(=O)C3=C(C2=O)C(=CC=C3)O	IC50 > 374100 nM	Non binder
T31391	Dipeptidyl peptidase 4	B76FGO	2-(S)-Amino-4-(cyclohexylmethyl-amino)-1-piperidin-1-yl-butan-1-one	Investigative	11266019	C16H31N3O	281.44	C1CCC(CC1)CNCC[C@@H](C(=O)N2CCCCC2)N	IC50 = 496000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B7GH2J	1H-Isoindole-1,3(2H)-dione, 2-[2,6-bis(1-methylethyl)phenyl]-4-nitro-	Investigative	20038035	C20H20N2O4	352.4	CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=O)C3=C(C2=O)C(=CC=C3)[N+](=O)[O-]	IC50 > 283800 nM	Non binder
T31391	Dipeptidyl peptidase 4	B83VKR	2,4-Diamino-1-thiazolidin-3-yl-butan-1-one	Investigative	44364296	C7H15N3OS	189.28	C1CSCN1C(=O)C(CCN)N	IC50 = 289000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B84QWX	(S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-methyl-piperidin-1-yl)-butan-1-one	Investigative	11381726	C17H26ClN3O	323.9	CC1CCCN(C1)C(=O)[C@H](CCNCC2=CC=C(C=C2)Cl)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B8BJ7Z	Fluoro-Olefin Analogue 11	Investigative	23646090	C14H18FN	219.3	C1CCC(=C(CNC2=CC=CC=C2)F)CC1	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B8KRP1	Ethyl 1-[(dimethylamino)methyl]-6,7-dimethoxyisoquinoline-4-carboxylate;hydrochloride	Investigative	45259934	C17H23ClN2O4	354.8	CCOC(=O)C1=CN=C(C2=CC(=C(C=C21)OC)OC)CN(C)C.Cl	IC50 = 948000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B8R6TU	2-(2,6-Dimethylphenyl)-5-nitro-1H-isoindole-1,3(2H)-dione	Investigative	477696	C16H12N2O4	296.28	CC1=C(C(=CC=C1)C)N2C(=O)C3=C(C2=O)C=C(C=C3)[N+](=O)[O-]	IC50 > 337500 nM	Non binder
T31391	Dipeptidyl peptidase 4	B8YTM3	(S)-2-Amino-4-(4-chloro-benzylamino)-1-(4-methyl-piperidin-1-yl)-butan-1-one	Investigative	10403949	C17H26ClN3O	323.9	CC1CCN(CC1)C(=O)[C@H](CCNCC2=CC=C(C=C2)Cl)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B94NMG	Ethyl 1-(aminomethyl)-6-methoxyisoquinoline-4-carboxylate;hydrochloride	Investigative	45259946	C14H17ClN2O3	296.75	CCOC(=O)C1=CN=C(C2=C1C=C(C=C2)OC)CN.Cl	IC50 = 207000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B95RMJ	2-Amino-3-methyl-pentanoic acid diethylamide	Investigative	17763521	C10H22N2O	186.29	CCC(C)C(C(=O)N(CC)CC)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B9OEH4	((2S,4R)-4-(Dibenzylamino)pyrrolidin-2-yl)(isoindolin-2-yl)methanone	Investigative	44560749	C27H29N3O	411.5	C1[C@H](CN[C@@H]1C(=O)N2CC3=CC=CC=C3C2)N(CC4=CC=CC=C4)CC5=CC=CC=C5	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B9QY7C	(2S)-2-Amino-1-(2-diphenoxyphosphorylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)propan-1-one	Investigative	11037548	C22H25N4O4P	440.4	C1CC(N(C1)C(=O)[C@H](CC2=CN=CN2)N)P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4	IC50 = 326000 nM	Non binder
T31391	Dipeptidyl peptidase 4	B9XQ2Z	2,6-Diamino-1-(3-hydroxy-pyrrolidin-1-yl)-hexan-1-one	Investigative	44364458	C10H21N3O2	215.29	C1CN(CC1O)C(=O)C(CCCCN)N	IC50 = 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BA5S7T	2-(S)-Amino-4-benzylamino-1-piperidin-1-yl-butan-1-one	Investigative	9817010	C16H25N3O	275.39	C1CCN(CC1)C(=O)[C@H](CCNCC2=CC=CC=C2)N	IC50 = 247000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BB02TU	Benzoic acid 1-(2-amino-3-methyl-pentanoyl)-pyrrolidin-3-yl ester	Investigative	44364446	C17H24N2O3	304.4	CCC(C)C(C(=O)N1CCC(C1)OC(=O)C2=CC=CC=C2)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BB17VA	N-(1,3-Benzodioxol-5-ylmethyl)-2-pyrrolidin-1-ylethanamine	Investigative	42773972	C14H20N2O2	248.32	C1CCN(C1)CCNCC2=CC3=C(C=C2)OCO3	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BC2HX7	2-(S)-Amino-4-(2-methoxy-benzylamino)-1-piperidin-1-yl-butan-1-one	Investigative	11150893	C17H27N3O2	305.4	COC1=CC=CC=C1CNCC[C@@H](C(=O)N2CCCCC2)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BC78BY	(2S)-2-Amino-1-(2-diphenoxyphosphorylpyrrolidin-1-yl)-3-hydroxy-propan-1-one	Investigative	11731880	C19H23N2O5P	390.4	C1CC(N(C1)C(=O)[C@H](CO)N)P(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3	IC50 = 503000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BE7KO5	Diphenyl 1-((S)-2,4-diaminobutanoyl)pyrrolidin-2-ylphosphonate	Investigative	44435310	C20H26N3O4P	403.4	C1CC(N(C1)C(=O)[C@H](CCN)N)P(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3	IC50 = 261000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BEGH78	2-(2,6-Diisopropyl-phenyl)-isoindole-1,3-dione	Investigative	9995375	C20H21NO2	307.4	CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=O)C3=CC=CC=C3C2=O	IC50 > 325300 nM	Non binder
T31391	Dipeptidyl peptidase 4	BEV48M	(2S,4R)-4-(4-Chlorobenzylamino)-2-amino-1-(piperidin-1-yl)pentan-1-one	Investigative	44415883	C17H26ClN3O	323.9	C[C@H](C[C@@H](C(=O)N1CCCCC1)N)NCC2=CC=C(C=C2)Cl	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BF5B6S	2-(2-Methylsulfanyl-phenyl)-4-nitro-isoindole-1,3-dione	Investigative	44368726	C15H10N2O4S	314.3	CSC1=CC=CC=C1N2C(=O)C3=C(C2=O)C(=CC=C3)[N+](=O)[O-]	IC50 > 318200 nM	Non binder
T31391	Dipeptidyl peptidase 4	BF92CP	(2S)-2-Amino-4-[(2,4-dimethoxyphenyl)methylamino]-1-piperidin-1-ylbutan-1-one	Investigative	11473127	C18H29N3O3	335.4	COC1=CC(=C(C=C1)CNCC[C@@H](C(=O)N2CCCCC2)N)OC	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BF9NS8	1-(3-Cyclohexyl-propionyl)-pyrrolidine-2-carbonitrile	Investigative	11117990	C14H22N2O	234.34	C1CCC(CC1)CCC(=O)N2CCC[C@H]2C#N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BFD8C9	2-[(Z)-1-Fluoro-2-(phenethylamino)ethylidene]cyclopentanecarbonitrile	Investigative	10872395	C16H19FN2	258.329	C1CC(/C(=C(/CNCCC2=CC=CC=C2)\\F)/C1)C#N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BFQW09	Di-(4-acetamido)phenyl 2-((S)-2,6-diaminohexanoyl)isoindolin-1-ylphosphonate	Investigative	23655476	C30H36N5O6P	593.6	CC(=O)NC1=CC=C(C=C1)OP(=O)(C2C3=CC=CC=C3CN2C(=O)[C@H](CCCCN)N)OC4=CC=C(C=C4)NC(=O)C	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BG1A7R	Fluoro-Olefin Analogue 7	Investigative	23646086	C19H27FN2	302.4	C1CCC(=C(CNC2CCN(CC2)CC3=CC=CC=C3)F)C1	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BG3U9D	((2S,4S)-4-(Benzylamino)pyrrolidin-2-yl)(isoindolin-2-yl)methanone	Investigative	44560698	C20H23N3O	321.4	C1[C@@H](CN[C@@H]1C(=O)N2CC3=CC=CC=C3C2)NCC4=CC=CC=C4	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BGL49M	(S)-2-Amino-4-dibenzylamino-1-piperidin-1-yl-butan-1-one	Investigative	11474019	C23H31N3O	365.5	C1CCN(CC1)C(=O)[C@H](CCN(CC2=CC=CC=C2)CC3=CC=CC=C3)N	IC50 = 266000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BH6XL1	(2H-1,3-Benzodioxol-5-ylmethyl)(2-cyclohexylidene-2-fluoroethyl)amine	Investigative	23646093	C16H20FNO2	277.33	C1CCC(=C(CNCC2=CC3=C(C=C2)OCO3)F)CC1	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BHDS65	2-Amino-3-methyl-pentanoic acid methyl-propyl-amide	Investigative	43271345	C10H22N2O	186.29	CCCN(C)C(=O)C(C(C)CC)N	IC50 = 377000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BJ14VB	2-Amino-2-cyclohexyl-1-piperidin-1-yl-ethanone	Investigative	44364133	C13H24N2O	224.34	C1CCC(CC1)C(C(=O)N2CCCCC2)N	IC50 = 217000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BJ6E4F	N-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butyl)-benzamide	Investigative	11300739	C16H23N3O2	289.37	C1CCN(CC1)C(=O)[C@H](CCNC(=O)C2=CC=CC=C2)N	IC50 = 418000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BJ7QB3	2,5-Diamino-1-piperidin-1-yl-pentan-1-one	Investigative	10081481	C10H21N3O	199.29	C1CCN(CC1)C(=O)C(CCCN)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BJAF95	Diphenyl 2-((2S,3S)-2-amino-3-methylpentanoyl)isoindolin-1-ylphosphonate	Investigative	23657402	C26H29N2O4P	464.5	CC[C@H](C)[C@@H](C(=O)N1CC2=CC=CC=C2C1P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4)N	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BJN02P	2-Amino-1-piperidin-1-yl-pentan-1-one	Investigative	43650152	C10H20N2O	184.28	CCCC(C(=O)N1CCCCC1)N	IC50 = 229000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BK1T6Y	(2S)-2-Amino-4-(naphthalen-1-ylmethylamino)-1-piperidin-1-ylbutan-1-one	Investigative	11209569	C20H27N3O	325.4	C1CCN(CC1)C(=O)[C@H](CCNCC2=CC=CC3=CC=CC=C32)N	IC50 = 301000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BL0B8W	2,4-Diamino-1-piperidin-1-yl-butan-1-one	Investigative	24906298	C9H19N3O	185.27	C1CCN(CC1)C(=O)C(CCN)N	IC50 = 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BL67JA	Pyrrolidin-1-yl-(tetrahydro-thiophen-2-yl)-methanone	Investigative	44364227	C9H15NOS	185.29	C1CCN(C1)C(=O)C2CCCS2	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BM4BI3	Pyrrolidin-2-yl-pyrrolidin-1-yl-methanethione	Investigative	44328319	C9H16N2S	184.3	C1CCN(C1)C(=S)C2CCCN2	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BM5FI2	1-Isoleucylhexahydro-1H-azepine	Investigative	10798619	C12H24N2O	212.33	CC[C@H](C)[C@@H](C(=O)N1CCCCCC1)N	IC50 = 374000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BN5SP7	2,6-Dimethylphenylphthalimide	Investigative	73324	C16H13NO2	251.28	CC1=C(C(=CC=C1)C)N2C(=O)C3=CC=CC=C3C2=O	IC50 > 398000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BNVL16	1-{2-[2-(5-Cyano-pyridin-2-ylamino)-ethylamino]-acetyl}-pyrrolidine-2-carboxylic acid amide	Investigative	10980018	C15H20N6O2	316.36	C1C[C@H](N(C1)C(=O)CNCCNC2=NC=C(C=C2)C#N)C(=O)N	IC50 = 434000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BOD38Z	(2E)-2-(1-Fluoro-2-{[(4-fluorophenyl)methyl]amino}ethylidene)cyclopentane-1-carbonitrile	Investigative	11025199	C15H16F2N2	262.3	C1CC(/C(=C(\\CNCC2=CC=C(C=C2)F)/F)/C1)C#N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BOZ4X6	1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrrolidine-2-carboxylic acid amide	Investigative	11067211	C17H27N3O3	321.4	C1C[C@H](N(C1)C(=O)CNC23C[C@H]4C[C@@H](C2)CC(C4)(C3)O)C(=O)N	IC50 = 931000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BP7X3Y	2,6-Diamino-1-piperidin-1-yl-hexan-1-one	Investigative	18398588	C11H23N3O	213.32	C1CCN(CC1)C(=O)C(CCCCN)N	IC50 = 247000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BPG50Z	1-[2-(3-Hydroxy-adamantan-1-ylamino)-acetyl]-pyrrolidine-2-carboxylic acid	Investigative	11023706	C17H26N2O4	322.4	C1C[C@H](N(C1)C(=O)CNC23C[C@H]4C[C@@H](C2)CC(C4)(C3)O)C(=O)O	IC50 = 477000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BPN25Z	Fluoro-Olefin Analogue 19	Investigative	23646098	C20H29FN2	316.5	C1CCC(=C(CNC2CCN(CC2)CC3=CC=CC=C3)F)CC1	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BQ67ZI	Ethyl 6,7-dimethoxy-1-(methylaminomethyl)isoquinoline-4-carboxylate;hydrochloride	Investigative	45259942	C16H21ClN2O4	340.8	CCOC(=O)C1=CN=C(C2=CC(=C(C=C21)OC)OC)CNC.Cl	IC50 = 731000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BR94VL	2-Cyclohexylamino-1-piperidin-1-yl-propan-1-one	Investigative	10376940	C14H26N2O	238.37	C1CCC(CC1)C[C@@H](C(=O)N2CCCCC2)N	IC50 = 217000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BRC02F	(2S)-2-Amino-1-piperidin-1-yl-4-(thiophen-2-ylmethylamino)butan-1-one	Investigative	11312069	C14H23N3OS	281.42	C1CCN(CC1)C(=O)[C@H](CCNCC2=CC=CS2)N	IC50 = 278000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BRF50K	((2S,4R)-4-Aminopyrrolidin-2-yl)(isoindolin-2-yl)methanone	Investigative	44560747	C13H17N3O	231.29	C1[C@H](CN[C@@H]1C(=O)N2CC3=CC=CC=C3C2)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BRU6V0	(2-Cyclohexylidene-2-fluoroethyl)[(4-fluorophenyl)methyl]amine	Investigative	23646094	C15H19F2N	251.31	C1CCC(=C(CNCC2=CC=C(C=C2)F)F)CC1	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BS4GF2	(S)-1-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)acetyl)pyrrolidine-2-carbonitrile	Investigative	44580500	C16H19N3O	269.34	C1C[C@H](N(C1)C(=O)CN2CCC3=CC=CC=C3C2)C#N	IC50 = 390000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BSL12E	2-Amino-3-methyl-pentanoic acid dimethylamide	Investigative	24710701	C8H18N2O	158.24	CCC(C)C(C(=O)N(C)C)N	IC50 = 360000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BT3E5L	N-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butyl)-guanidine	Investigative	10059633	C10H21N5O	227.31	C1CCN(CC1)C(=O)[C@H](CCN=C(N)N)N	IC50 = 545000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BTGU28	(S)-4-(4-Chloro-benzylamino)-2-methylamino-1-piperidin-1-yl-butan-1-one	Investigative	11472776	C17H26ClN3O	323.9	CN[C@@H](CCNCC1=CC=C(C=C1)Cl)C(=O)N2CCCCC2	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BU7F9X	1H-Isoindole-1,3(2H)-dione, 2-[2,6-bis(1-methylethyl)phenyl]-5-nitro-	Investigative	13784835	C20H20N2O4	352.4	CC(C)C1=C(C(=CC=C1)C(C)C)N2C(=O)C3=C(C2=O)C=C(C=C3)[N+](=O)[O-]	IC50 > 283800 nM	Non binder
T31391	Dipeptidyl peptidase 4	BUYS91	(S)-Benzyl 5-amino-6-(isoindolin-2-yl)-6-oxohexylcarbamate	Investigative	44593409	C22H27N3O3	381.5	C1C2=CC=CC=C2CN1C(=O)[C@H](CCCCNC(=O)OCC3=CC=CC=C3)N	IC50 = 245000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BV2N9S	Ethyl 1-(2-aminoethyl)-6,7-dimethoxyisoquinoline-4-carboxylate;2,2,2-trifluoroacetic acid	Investigative	44286479	C18H21F3N2O6	418.4	CCOC(=O)C1=CN=C(C2=CC(=C(C=C21)OC)OC)CCN.C(=O)(C(F)(F)F)O	IC50 = 746000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BVB19K	(S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-fluoro-piperidin-1-yl)-butan-1-one	Investigative	11450266	C16H23ClFN3O	327.82	C1CC(CN(C1)C(=O)[C@H](CCNCC2=CC=C(C=C2)Cl)N)F	IC50 = 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BWK38T	(R)-1-(2-Pivalamidoacetyl)pyrrolidin-2-ylboronic acid	Investigative	15951928	C11H21BN2O4	256.11	B([C@@H]1CCCN1C(=O)CNC(=O)C(C)(C)C)(O)O	Ki = 608000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BWL13O	N-[4-[(4-Acetamidophenoxy)-[2-[(2S,3R)-2-amino-3-methylpentanoyl]-1,3-dihydroisoindol-1-yl]phosphoryl]oxyphenyl]acetamide	Investigative	23657547	C30H35N4O6P	578.6	CC[C@@H](C)[C@@H](C(=O)N1CC2=CC=CC=C2C1P(=O)(OC3=CC=C(C=C3)NC(=O)C)OC4=CC=C(C=C4)NC(=O)C)N	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BX8ZL1	2-(S)-Amino-4-(4-methoxy-benzylamino)-1-piperidin-1-yl-butan-1-one	Investigative	11255193	C17H27N3O2	305.4	COC1=CC=C(C=C1)CNCC[C@@H](C(=O)N2CCCCC2)N	IC50 = 417000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BXG5J0	Ubenimex	Investigative	72172	C16H24N2O4	308.37	CC(C)C[C@@H](C(=O)O)NC(=O)[C@H]([C@@H](CC1=CC=CC=C1)N)O	IC50 > 324300 nM	Non binder
T31391	Dipeptidyl peptidase 4	BY96WI	(2S)-2-Amino-4-[(2-phenylmethoxyphenyl)methylamino]-1-piperidin-1-ylbutan-1-one	Investigative	11383468	C23H31N3O2	381.5	C1CCN(CC1)C(=O)[C@H](CCNCC2=CC=CC=C2OCC3=CC=CC=C3)N	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BZ1T7H	6-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butylamino)-nicotinonitrile	Investigative	11289193	C15H21N5O	287.36	C1CCN(CC1)C(=O)[C@H](CCNC2=NC=C(C=C2)C#N)N	IC50 = 205000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BZ5A9C	(2-Cyclohexylidene-2-fluoroethyl)[(4-methoxyphenyl)methyl]amine	Investigative	23646092	C16H22FNO	263.35	COC1=CC=C(C=C1)CNCC(=C2CCCCC2)F	IC50 > 250000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BZ5RL3	2-Amino-3-(1H-imidazol-4-yl)-1-piperidin-1-yl-propan-1-one	Investigative	44328318	C11H18N4O	222.29	C1CCN(CC1)C(=O)C(CC2=CN=CN2)N	IC50 = 213000 nM	Non binder
T31391	Dipeptidyl peptidase 4	BZF76U	Diphenyl 2-((S)-2,6-diaminohexanoyl)isoindolin-1-ylphosphonate	Investigative	23655298	C26H30N3O4P	479.5	C1C2=CC=CC=C2C(N1C(=O)[C@H](CCCCN)N)P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4	IC50 > 500000 nM	Non binder
T31391	Dipeptidyl peptidase 4	D00YEV	BAICALEIN	Investigative	5281605	C15H10O5	270.24	C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O	IC50 > 200000 nM	Non binder
T31391	Dipeptidyl peptidase 4	D0JL2T	3,7-dihydroxy-flavone	Investigative	5393152	C15H10O4	254.24	C1=CC=C(C=C1)C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O	IC50 > 200000 nM	Non binder