TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T55922	S-adenosylmethionine decarboxylase proenzyme	B06UOD	Chembl1163096	Investigative	118725250	C15H21N7O3S	379.4	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CSCCCC(C#N)N)O)O)N	IC50 = 204800 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B19AEJ	(2R,3R,4S,5R)-2-[6-Amino-8-(methylamino)-9H-purin-9-yl]-5-{[(3-aminopropyl)(methyl)amino]methyl}oxolane-3,4-diol	Investigative	25231819	C15H26N8O3	366.42	CNC1=NC2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CN(C)CCCN)O)O)N	IC50 = 440000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B2LA1W	(2R,3R,4S,5R)-2-(6-Amino-8-ethylpurin-9-yl)-5-[[3-aminopropyl(methyl)amino]methyl]oxolane-3,4-diol;sulfuric acid	Investigative	44564339	C16H29N7O7S	463.5	CCC1=NC2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CN(C)CCCN)O)O)N.OS(=O)(=O)O	IC50 = 420000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B7EGY6	Chembl605698	Investigative	118725241	C14H22N6O7S2	450.5	C1CNCC1SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O.OS(=O)(=O)O	Ki = 415000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B90GPU	Chembl605267	Investigative	118725243	C15H22N6O9S2	494.5	C1[C@H](CN[C@@H]1C(=O)O)SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O.OS(=O)(=O)O	Ki = 960000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BI7H6R	Chembl606102	Investigative	118725235	C15H26N6O11S3	562.6	C[S+](C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)C4CCNC4.OS(=O)(=O)O.OS(=O)(=O)[O-]	Ki = 669000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BJ9I3Z	Chembl605899	Investigative	118725238	C15H22N6O9S2	494.5	C1[C@@H](CN[C@@H]1C(=O)O)SC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O.OS(=O)(=O)O	Ki = 478000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BJFR31	[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[(3R,5S)-5-carboxypyrrolidin-3-yl]-methylsulfanium;hydrogen sulfate;sulfuric acid	Investigative	118705586; 118725236	C16H26N6O13S3	606.6	C[S+](C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)[C@@H]4C[C@H](NC4)C(=O)O.OS(=O)(=O)O.OS(=O)(=O)[O-]	Ki = 1070000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BKG83A	(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-{[(3-aminopropyl)(methyl)amino]methyl}oxolane-3,4-diol	Investigative	25231821	C14H23N7O3	337.38	CN(CCCN)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O	IC50 = 500000 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BOP09F	Chembl541928	Investigative	118725211	C15H23Br2N7O3S	541.3	C[S+](CCC(C#N)N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O.Br.[Br-]	Ki = 246600 nM	Non binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BZ2JV3	[(2S,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-[(5S)-5-carboxypyrrolidin-3-yl]-methylsulfanium;hydrogen sulfate;sulfuric acid	Investigative	118725236	C16H26N6O13S3	606.6	C[S+](C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)C4C[C@H](NC4)C(=O)O.OS(=O)(=O)O.OS(=O)(=O)[O-]	Ki = 1207000 nM	Non binder