TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T57700	Tyrosine-protein kinase Kit	D08CDI	Lapatinib	Approved	208908	C29H26ClFN4O4S	581.1	CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B18RDA	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[2-methylsulfonyl-1-(propan-2-ylamino)ethyl]furan-2-yl]quinazolin-4-amine	Investigative	118717615	C31H30ClFN4O4S	609.1	CC(C)NC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B2GI7T	[[(1S)-1-[5-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-yl]-2-methylsulfonylethyl]amino] propanoate	Investigative	118717617	C31H28ClFN4O6S	639.1	CCC(=O)ON[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B35AQR	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(ethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	56640588	C30H28ClFN4O4S	595.1	CCNC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B4H7TR	[[(1S)-1-[5-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-yl]-2-methylsulfonylethyl]amino] pentanoate	Investigative	118717618	C33H32ClFN4O6S	667.1	CCCCC(=O)ON[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B4ND6W	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[2-methylsulfonyl-1-(2-methylsulfonylethylamino)ethyl]furan-2-yl]quinazolin-4-amine	Investigative	118717616	C31H30ClFN4O6S2	673.2	CS(=O)(=O)CCNC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B5JP4Y	6-[5-(1-Amino-2-methylsulfonylethyl)furan-2-yl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine	Investigative	56640590	C28H24ClFN4O4S	567	CS(=O)(=O)CC(C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)N	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B8V5AJ	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(cyclohexylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	118717614	C34H34ClFN4O4S	649.2	CS(=O)(=O)CC(C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)NC6CCCCC6	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	B8YC0L	CID 46866615	Investigative	46866615	C28H24ClFN4O4S	567	CS(=O)(=O)C[C@@H](C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)N	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	BCLV75	[[(1S)-1-[5-[4-[3-Chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-yl]-2-methylsulfonylethyl]amino] heptanoate	Investigative	118717619	C35H36ClFN4O6S	695.2	CCCCCCC(=O)ON[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	BI1B6L	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(1R)-1-(dimethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	46865445	C30H28ClFN4O4S	595.1	CN(C)[C@@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	BI1HX2	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(1S)-1-(dimethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	46865125	C30H28ClFN4O4S	595.1	CN(C)[C@H](CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	BOD1W4	CID 46866616	Investigative	46866616	C28H24ClFN4O4S	567	CS(=O)(=O)C[C@H](C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl)N	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	BQR5H8	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(methylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	56640518	C29H26ClFN4O4S	581.1	CNC(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	BSEB16	2-[[1-Cyclopentyl-5-[1-(Oxetan-3-Yl)piperidin-4-Yl]pyrazol-3-Yl]amino]pyridine-4-Carbonitrile	Investigative	91936970	C22H28N6O	392.5	C1CCC(C1)N2C(=CC(=N2)NC3=NC=CC(=C3)C#N)C4CCN(CC4)C5COC5	IC50 = 534000 nM	Non binder
T57700	Tyrosine-protein kinase Kit	BU2D0R	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[1-(dimethylamino)-2-methylsulfonylethyl]furan-2-yl]quinazolin-4-amine	Investigative	56640520	C30H28ClFN4O4S	595.1	CN(C)C(CS(=O)(=O)C)C1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl	IC50 > 200000 nM	Non binder