TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T62184	GABA transporter GAT-1	B01XGU	2,4-Dichloro-N-{1-[(pyridin-2-yl)methyl]piperidin-4-yl}benzamide	Investigative	47058964	C18H19Cl2N3O	364.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=N3	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	B04AGQ	Tert-butyl 2-[4-[(2,4-dichlorobenzoyl)amino]piperidin-1-yl]acetate	Investigative	137651374	C18H24Cl2N2O3	387.3	CC(C)(C)OC(=O)CN1CCC(CC1)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	B0L6AI	1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid	Investigative	9983570	C30H33NO6	503.6	COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)OCCN4CCC=C(C4)C(=O)O	IC50 = 268000 nM	Non binder
T62184	GABA transporter GAT-1	B1RV5K	2,4-Dichloro-N-[1-(pyridin-3-ylmethyl)piperidin-4-yl]benzamide	Investigative	137637846	C18H19Cl2N3O	364.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CN=CC=C3	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	B1Y8RO	2,4-Dichloro-N-[1-(3-diethoxyphosphorylpropyl)piperidin-4-yl]benzamide	Investigative	137639281	C19H29Cl2N2O4P	451.3	CCOP(=O)(CCCN1CCC(CC1)NC(=O)C2=C(C=C(C=C2)Cl)Cl)OCC	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	B24HDT	(3R,8R)-8-Benzhydryl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine-3-carboxylic acid;hydrochloride	Investigative	70689233	C23H28ClNO2	385.9	C1CC2C[C@@H](CCN2C[C@@H]1C(=O)O)C(C3=CC=CC=C3)C4=CC=CC=C4.Cl	IC50 = 632000 nM	Non binder
T62184	GABA transporter GAT-1	B24YZS	2-Ethoxy-N-[1-(phenylmethyl)-4-piperidinyl]benzamide	Investigative	8181355	C21H26N2O2	338.4	CCOC1=CC=CC=C1C(=O)NC2CCN(CC2)CC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T62184	GABA transporter GAT-1	B39IXZ	2,4-Dichloro-N-[1-(pyridin-4-ylmethyl)piperidin-4-yl]benzamide	Investigative	137650102	C18H19Cl2N3O	364.3	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=NC=C3	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	B5VBR9	1-Benzyl-N-[(2,4-dichlorophenyl)methyl]piperidin-4-amine	Investigative	17159064	C19H22Cl2N2	349.3	C1CN(CCC1NCC2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3	IC50 > 400000 nM	Non binder
T62184	GABA transporter GAT-1	B7KA4R	(R)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid	Investigative	6604883	C30H35NO6	505.6	COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)OCCN4CCC[C@H](C4)C(=O)O	IC50 = 439000 nM	Non binder
T62184	GABA transporter GAT-1	B8BZK4	1-Benzyl-piperidin-4-yl benzoate	Investigative	15124790	C19H21NO2	295.4	C1CN(CCC1OC(=O)C2=CC=CC=C2)CC3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BA5BR3	N-(1-Benzylpiperidin-4-yl)benzamide	Investigative	40598	C19H22N2O	294.4	C1CN(CCC1NC(=O)C2=CC=CC=C2)CC3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BAF63S	2,4-Dichloro-N-(1-ethylpiperidin-4-yl)benzamide	Investigative	17174058	C14H18Cl2N2O	301.2	CCN1CCC(CC1)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BAU58Z	N-(1-Benzylpiperidin-4-yl)-3-(trifluoromethyl)benzamide	Investigative	17250318	C20H21F3N2O	362.4	C1CN(CCC1NC(=O)C2=CC(=CC=C2)C(F)(F)F)CC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T62184	GABA transporter GAT-1	BBA38E	2,4-Dichloro-N-(1-methylpiperidin-4-yl)benzamide	Investigative	639062	C13H16Cl2N2O	287.18	CN1CCC(CC1)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BBH5A6	(3R)-8-Benzhydrylidene-1,2,3,4,6,7,9,9a-octahydroquinolizine-3-carboxylic acid;hydrochloride	Investigative	70691308	C23H26ClNO2	383.9	C1CC2CC(=C(C3=CC=CC=C3)C4=CC=CC=C4)CCN2C[C@@H]1C(=O)O.Cl	IC50 = 270000 nM	Non binder
T62184	GABA transporter GAT-1	BD23TL	N-(1-Benzylpiperidin-4-yl)-4-fluorobenzamide	Investigative	702501	C19H21FN2O	312.4	C1CN(CCC1NC(=O)C2=CC=C(C=C2)F)CC3=CC=CC=C3	IC50 > 300000 nM	Non binder
T62184	GABA transporter GAT-1	BDV06W	2,4-Dichloro-N-[1-(3-cyanopropyl)piperidin-4-yl]benzamide	Investigative	137650910	C16H19Cl2N3O	340.2	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CCCC#N	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BF46GZ	N-(1-Benzylpiperidin-4-yl)-2,6-dichloropyridine-3-carboxamide	Investigative	137635197	C18H19Cl2N3O	364.3	C1CN(CCC1NC(=O)C2=C(N=C(C=C2)Cl)Cl)CC3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BK79IQ	(3S)-8-Benzhydrylidene-1,2,3,4,6,7,9,9a-octahydroquinolizine-3-carboxylic acid;hydrochloride	Investigative	70684990	C23H26ClNO2	383.9	C1CC2CC(=C(C3=CC=CC=C3)C4=CC=CC=C4)CCN2C[C@H]1C(=O)O.Cl	IC50 = 809000 nM	Non binder
T62184	GABA transporter GAT-1	BOL61T	(3S,8R)-8-Benzhydryl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine-3-carboxylic acid;hydrochloride	Investigative	70691306	C23H28ClNO2	385.9	C1CC2C[C@@H](CCN2C[C@H]1C(=O)O)C(C3=CC=CC=C3)C4=CC=CC=C4.Cl	IC50 = 270000 nM	Non binder
T62184	GABA transporter GAT-1	BOU75T	2,4-Dichloro-N-piperidin-4-ylbenzamide	Investigative	43345728	C12H14Cl2N2O	273.15	C1CNCCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BR0IN1	(1-Benzylpiperidin-4-yl) 2,4-dichlorobenzoate	Investigative	137650733	C19H19Cl2NO2	364.3	C1CN(CCC1OC(=O)C2=C(C=C(C=C2)Cl)Cl)CC3=CC=CC=C3	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BRMG32	N-(1-Benzylpiperidin-4-yl)-2,3-dimethoxybenzamide	Investigative	13314232	C21H26N2O3	354.4	COC1=CC=CC(=C1OC)C(=O)NC2CCN(CC2)CC3=CC=CC=C3	IC50 > 500000 nM	Non binder
T62184	GABA transporter GAT-1	BS1KV0	2,4-Dichloro-N-(1-propylpiperidin-4-yl)benzamide	Investigative	17173775	C15H20Cl2N2O	315.2	CCCN1CCC(CC1)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BSN5K4	1-[2-[Tris(4-methoxyphenyl)methoxy]ethyl]piperidine-3-carboxylic acid	Investigative	4531494	C30H35NO6	505.6	COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=C(C=C3)OC)OCCN4CCCC(C4)C(=O)O	IC50 = 233000 nM	Non binder
T62184	GABA transporter GAT-1	BUTF86	2,4-Dichloro-N-(1-prop-2-ynylpiperidin-4-yl)benzamide	Investigative	137651669	C15H16Cl2N2O	311.2	C#CCN1CCC(CC1)NC(=O)C2=C(C=C(C=C2)Cl)Cl	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BW3N0X	N-(1-Benzylpiperidin-4-yl)-2-methylpropanamide	Investigative	1530639	C16H24N2O	260.37	CC(C)C(=O)NC1CCN(CC1)CC2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T62184	GABA transporter GAT-1	BX5LG2	2-[4-[(2,4-Dichlorobenzoyl)amino]piperidin-1-yl]acetic acid	Investigative	137652511	C14H16Cl2N2O3	331.2	C1CN(CCC1NC(=O)C2=C(C=C(C=C2)Cl)Cl)CC(=O)O	IC50 > 1000000 nM	Non binder