TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T83193 Transient receptor potential cation channel V1 B61ZLR 19(S)-Heyneanine Investigative 44566752 C22H28N2O4 384.5 C[C@@H]([C@H]1C[C@H]2C[C@@]3([C@H]1N(C2)CCC4=C3NC5=C4C=C(C=C5)OC)C(=O)OC)O IC50 > 200000 nM Non binder T83193 Transient receptor potential cation channel V1 B6OP8A Benzyl isothiocyanate Investigative 2346 C8H7NS 149.21 C1=CC=C(C=C1)CN=C=S EC50 = 223000 nM Non binder T83193 Transient receptor potential cation channel V1 BBQZ70 Methyl (1S,14R,16S,17S)-16-ethyl-7-methoxy-3-(methoxymethyl)-10,12-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2,4(9),5,7-tetraene-1-carboxylate Investigative 118711168 C23H30N2O4 398.5 CC[C@H]1C[C@@H]2C[C@@]3([C@H]1N(C2)CN4C3=C(C5=C4C=C(C=C5)OC)COC)C(=O)OC IC50 > 200000 nM Non binder T83193 Transient receptor potential cation channel V1 BD8E6J Nobilamide A Investigative 53259578 C42H59N7O10 822 C/C=C(/C(=O)O)\\NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)C IC50 = 1665000 nM Non binder T83193 Transient receptor potential cation channel V1 BF58QW (2R)-2-[[(2R)-2-Acetamido-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(3Z,6S,9S,12R,13R)-3-ethylidene-6,13-dimethyl-2,5,8,11-tetraoxo-9-propan-2-yl-1-oxa-4,7,10-triazacyclotridec-12-yl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methylpentanamide Investigative 54587294 C42H57N7O9 803.9 C/C=C\\1/C(=O)O[C@@H]([C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)C)C(C)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC3=CC=CC=C3)NC(=O)C)C IC50 = 1320000 nM Non binder T83193 Transient receptor potential cation channel V1 BJK5U4 Chembl4226595 Investigative 21404983 C13H19NO3 237.29 CC(C)(C)C(=O)NCCC1=CC(=C(C=C1)O)O EC50 > 500000 nM Non binder T83193 Transient receptor potential cation channel V1 BM2CE0 [2-[2-(5-Hydroxy-1H-indol-3-yl)ethylcarbamoyl]phenyl] acetate Investigative 118723540 C19H18N2O4 338.4 CC(=O)OC1=CC=CC=C1C(=O)NCCC2=CNC3=C2C=C(C=C3)O IC50 = 203000 nM Non binder T83193 Transient receptor potential cation channel V1 BWQ2K7 Nobilamide B Investigative 53257733 C43H61N7O10 836 CCC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N/C(=C\\C)/C(=O)O IC50 = 275000 nM Non binder T83193 Transient receptor potential cation channel V1 BZ96QX (2R)-N-[(2S)-1-[[(3Z,6S,9S,12R,13R)-3-Ethylidene-6,13-dimethyl-2,5,8,11-tetraoxo-9-propan-2-yl-1-oxa-4,7,10-triazacyclotridec-12-yl]amino]-1-oxo-3-phenylpropan-2-yl]-4-methyl-2-[[(2R)-3-phenyl-2-(propanoylamino)propanoyl]amino]pentanamide Investigative 54587295 C43H59N7O9 818 CCC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@H](OC(=O)/C(=C/C)/NC(=O)[C@@H](NC(=O)[C@@H](NC3=O)C(C)C)C)C IC50 = 227000 nM Non binder