TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T84631	Coagulation factor Xa	B03ZOI	3-Hydroxy-4-iodo-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304098	C22H17IN4O2	496.3	C1=CC=C2C=C3C(=CC2=C1)C=C(C(=C3I)O)C(=O)NC4=CC=C(C=C4)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	B0BHV5	N-[3-[(4-Fluorophenyl)methoxy]phenyl]-1-propan-2-ylpiperidine-4-carboxamide	Investigative	72711858	C22H27FN2O2	370.5	CC(C)N1CCC(CC1)C(=O)NC2=CC(=CC=C2)OCC3=CC=C(C=C3)F	Ki > 250000 nM	Non binder
T84631	Coagulation factor Xa	B0FPG3	(3S)-1-[2-(4-Chlorophenyl)acetyl]-N-methyl-N-[4-(2-oxopiperidin-1-yl)phenyl]piperidine-3-carboxamide	Investigative	66574037	C26H30ClN3O3	468	CN(C1=CC=C(C=C1)N2CCCCC2=O)C(=O)[C@H]3CCCN(C3)C(=O)CC4=CC=C(C=C4)Cl	IC50 = 371000 nM	Non binder
T84631	Coagulation factor Xa	B0IK7T	2-Chloro-benzenesulfonic acid 3-(3-guanidino-propoxy)-5-methyl-phenyl ester	Investigative	44287937	C17H20ClN3O4S	397.9	CC1=CC(=CC(=C1)OS(=O)(=O)C2=CC=CC=C2Cl)OCCCN=C(N)N	Ki > 200000 nM	Non binder
T84631	Coagulation factor Xa	B0KFM2	(3S)-N-Methyl-N-[4-(2-oxopiperidin-1-yl)phenyl]-2-[2-[4-(trifluoromethyl)phenyl]acetyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	Investigative	66573639	C31H30F3N3O3	549.6	CN(C1=CC=C(C=C1)N2CCCCC2=O)C(=O)[C@@H]3CC4=CC=CC=C4CN3C(=O)CC5=CC=C(C=C5)C(F)(F)F	IC50 = 335000 nM	Non binder
T84631	Coagulation factor Xa	B0NE4Z	Chembl4209404	Investigative	9859977	C13H6F2N2O2	260.19	C1=CC(=C(C(=C1)F)C2=NC3=C(C=CN=C3)C(=O)O2)F	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B12YBD	N-(4-Guanidino-phenyl)-2-hydroxy-5-methoxy-benzamide	Investigative	44304047	C15H16N4O3	300.31	COC1=CC(=C(C=C1)O)C(=O)NC2=CC=C(C=C2)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	B13HLB	N-(4-Guanidino-phenyl)-2-hydroxy-4-methyl-benzamide	Investigative	44304006	C17H20N4O2	312.37	CC1=CC(=C(C=C1)C(=O)N(C)C2=CC=C(C=C2)N=C(N)N)OC	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	B1KIC5	N-[(3S,7E,9S,12R,16S,19S)-16-[[3-(Aminomethyl)phenyl]methyl]-12-[(2S)-butan-2-yl]-9-[(4-hydroxyphenyl)methyl]-2,6,11,14,18-pentaoxo-1,5,10,13,17-pentazabicyclo[17.3.0]docos-7-en-3-yl]acetamide	Investigative	57395841	C38H51N7O7	717.9	CC[C@H](C)[C@@H]1C(=O)N[C@H](/C=C/C(=O)NC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](CC(=O)N1)CC3=CC(=CC=C3)CN)NC(=O)C)CC4=CC=C(C=C4)O	Ki = 310000 nM	Non binder
T84631	Coagulation factor Xa	B1YI7D	{(R)-2-[(S)-2-(4-Amino-benzylcarbamoyl)-pyrrolidin-1-yl]-1-benzyl-2-oxo-ethyl}-carbamic acid tert-butyl ester	Investigative	11798429	C26H34N4O4	466.6	CC(C)(C)OC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N2CCC[C@H]2C(=O)NCC3=CC=C(C=C3)N	Ki = 420000 nM	Non binder
T84631	Coagulation factor Xa	B26BID	3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(4-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide	Investigative	44569333	C26H38N6O4S	530.7	C1CN(CCC1CCN)C(=O)[C@H](CC2=CC=C(C=C2)CN)NS(=O)(=O)C3=CC=CC(=C3)NC(=O)CCN	Ki = 430000 nM	Non binder
T84631	Coagulation factor Xa	B2DR9B	(3S)-2-[3-(2,4-Dimethoxyphenyl)propanoyl]-N-methyl-N-[4-(3-oxomorpholin-4-yl)phenyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	Investigative	66573846	C32H35N3O6	557.6	CN(C1=CC=C(C=C1)N2CCOCC2=O)C(=O)[C@@H]3CC4=CC=CC=C4CN3C(=O)CCC5=C(C=C(C=C5)OC)OC	IC50 > 500000 nM	Non binder
T84631	Coagulation factor Xa	B2ND0A	Benzyl (3S)-3-[(4-piperidin-1-ylphenyl)carbamoyl]-3,4-dihydro-1H-isoquinoline-2-carboxylate	Investigative	66573911	C29H31N3O3	469.6	C1CCN(CC1)C2=CC=C(C=C2)NC(=O)[C@@H]3CC4=CC=CC=C4CN3C(=O)OCC5=CC=CC=C5	IC50 > 500000 nM	Non binder
T84631	Coagulation factor Xa	B2VPT6	5-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]carbamoyl]-2-[2-[(3-carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]benzoic acid	Investigative	44421845	C29H31N5O6	545.6	CC(C)C[C@@H](C(=O)N)NC(=O)C1=CC(=C(C=C1)C2=C(C=C(C=C2)NC)C(=O)NC3=CC=CC(=C3)C(=O)N)C(=O)O	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B3IC8Q	4-Bromo-3-hydroxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide	Investigative	44304086	C21H16BrN5O2	450.3	C1=CC=C2C=C3C(=CC2=C1)C=C(C(=C3Br)O)C(=O)NC4=CN=C(C=C4)N=C(N)N	Ki = 235000 nM	Non binder
T84631	Coagulation factor Xa	B3KQ2O	(2S)-2-[[(2S)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-4-methylpentanamide	Investigative	56666511	C36H48N6O5S	676.9	CC(C)C[C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NS(=O)(=O)CC3=CC=CC=C3	IC50 > 580000 nM	Non binder
T84631	Coagulation factor Xa	B4A5KU	4-Bromo-3-hydroxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304099	C22H17BrN4O2	449.3	C1=CC=C2C=C3C(=CC2=C1)C=C(C(=C3Br)O)C(=O)NC4=CC=C(C=C4)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	B4G3IV	N-(2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-[3-(4-fluoro-phenylmethanesulfonylamino)-6-methyl-2-oxo-2H-pyridin-1-yl]-acetamide	Investigative	10074892	C22H24FN5O4S2	505.6	CC1=CC=C(C(=O)N1CC(=O)NC2CCC3=C(C2)SC(=N3)N)NS(=O)(=O)CC4=CC=C(C=C4)F	Ki > 300000 nM	Non binder
T84631	Coagulation factor Xa	B4JEG3	5-Chloro-N-[2-oxo-2-[4-(3-oxomorpholin-4-yl)anilino]ethyl]thiophene-2-carboxamide	Investigative	10453208	C17H16ClN3O4S	393.8	C1COCC(=O)N1C2=CC=C(C=C2)NC(=O)CNC(=O)C3=CC=C(S3)Cl	IC50 = 700000 nM	Non binder
T84631	Coagulation factor Xa	B59GSO	N-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-guanidine	Investigative	44416510	C14H22BN3O2	275.16	B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)CN=C(N)N	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B5JE7T	N-(4-Guanidino-phenyl)-2-hydroxy-3-methyl-benzamide	Investigative	44304353	C15H16N4O2	284.31	CC1=C(C(=CC=C1)C(=O)NC2=CC=C(C=C2)N=C(N)N)O	Ki = 350000 nM	Non binder
T84631	Coagulation factor Xa	B5W6NO	(2S)-N-[(4-Aminocyclohexyl)methyl]-1-(3,3-diphenylpropanoyl)pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid	Investigative	44347573	C29H36F3N3O4	547.6	C1C[C@H](N(C1)C(=O)CC(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)NCC4CCC(CC4)N.C(=O)(C(F)(F)F)O	Ki = 980000 nM	Non binder
T84631	Coagulation factor Xa	B6JFW5	Chembl4216440	Investigative	9112697	C19H20N4O4S	400.5	CC1=CSC(=O)N1CC(=O)OCC(=O)NC2=C(N(N=C2C)C3=CC=CC=C3)C	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B6N4PI	(2S)-1-(5-Chlorothiophene-2-carbonyl)-N-methyl-N-[4-(2-oxopiperidin-1-yl)phenyl]piperidine-2-carboxamide	Investigative	66574099	C23H26ClN3O3S	460	CN(C1=CC=C(C=C1)N2CCCCC2=O)C(=O)[C@@H]3CCCCN3C(=O)C4=CC=C(S4)Cl	IC50 = 358000 nM	Non binder
T84631	Coagulation factor Xa	B6ST8W	(2S)-N-[(4-Aminocyclohexyl)methyl]-1-(3-phenyl-3-pyridin-2-ylpropanoyl)pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid	Investigative	44347533	C28H35F3N4O4	548.6	C1C[C@H](N(C1)C(=O)CC(C2=CC=CC=C2)C3=CC=CC=N3)C(=O)NCC4CCC(CC4)N.C(=O)(C(F)(F)F)O	Ki = 370000 nM	Non binder
T84631	Coagulation factor Xa	B72ZMX	3-Hydroxy-4-isopropoxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44303912	C25H24N4O3	428.5	CC(C)OC1=C(C(=CC2=CC3=CC=CC=C3C=C21)C(=O)NC4=CC=C(C=C4)N=C(N)N)O	Ki = 240000 nM	Non binder
T84631	Coagulation factor Xa	B78OUA	2-[3-(4-Fluoro-phenylmethanesulfonylamino)-6-methyl-2-oxo-2H-pyridin-1-yl]-N-(4,5,6,7-tetrahydro-2H-indazol-5-ylmethyl)-acetamide	Investigative	11648797	C23H26FN5O4S	487.5	CC1=CC=C(C(=O)N1CC(=O)NCC2CCC3=C(C2)C=NN3)NS(=O)(=O)CC4=CC=C(C=C4)F	Ki = 314000 nM	Non binder
T84631	Coagulation factor Xa	B79EXU	Sodium;[3-ethoxycarbonyl-2-[[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl]oxymethyl]-1H-indol-5-yl] sulfate	Investigative	118723908	C38H36NNaO16S	817.7	CCOC(=O)C1=C(OC2=CC(=C(C=C21)OCC3=C(C4=CC(=C(C=C4O3)OC)OCC5=C(C6=C(N5)C=CC(=C6)OS(=O)(=O)[O-])C(=O)OCC)C(=O)OCC)OC)C.[Na+]	IC50 = 344000 nM	Non binder
T84631	Coagulation factor Xa	B7CEB5	Chembl4211470	Investigative	16289649	C23H21N5O4	431.4	CC1=C(C(=NN1C2=CC=CC=C2)C)NC(=O)COC(=O)CN3C=NC4=CC=CC=C4C3=O	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B7LQ0P	(3R)-N-Methyl-N-[4-(2-oxopiperidin-1-yl)phenyl]-2-[2-[4-(trifluoromethyl)phenyl]acetyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	Investigative	66573710	C31H30F3N3O3	549.6	CN(C1=CC=C(C=C1)N2CCCCC2=O)C(=O)[C@H]3CC4=CC=CC=C4CN3C(=O)CC5=CC=C(C=C5)C(F)(F)F	IC50 = 311000 nM	Non binder
T84631	Coagulation factor Xa	B7LYX9	3alpha-(4-Amidinobutyl)-1,2,3,3aalpha,8,8abeta-hexahydroindeno[2,1-b]pyrrole-2-one	Investigative	44290501	C16H21N3O	271.36	C1[C@H]2[C@@H]([C@H](C(=O)N2)CCCCC(=N)N)C3=CC=CC=C31	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B7PFW8	Sodium;[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-2-methyl-1H-indol-5-yl)oxymethyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-5-yl] sulfate	Investigative	118723906	C29H31N2NaO11S	638.6	CCOC(=O)C1=C(NC2=C1C=C(C=C2)OCC3=C(C4=C(N3C(=O)OC(C)(C)C)C=CC(=C4)OS(=O)(=O)[O-])C(=O)OCC)C.[Na+]	IC50 = 229000 nM	Non binder
T84631	Coagulation factor Xa	B85DZR	(12E)-20-Amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,12,18,20,22,27(30),28-nonaen-26-one	Investigative	134131077	C29H33N7O3	527.6	CC1=C2CNC(=O)C3=CN(CC4=C(C=C(C=C4)CN5C=CC=N5)OCC/C=C/CCCOC2=CC(=N1)N)N=C3	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B8AFI9	4-Chloro-N-(4-guanidino-phenyl)-2-hydroxy-benzamide	Investigative	44304046	C14H13ClN4O2	304.73	C1=CC(=CC=C1NC(=O)C2=C(C=C(C=C2)Cl)O)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	B8EUF5	(2S)-2-[[(2R)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-3-phenylpropanamide	Investigative	56680051	C39H46N6O5S	710.9	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=CC=C3)NS(=O)(=O)CC4=CC=CC=C4	IC50 > 640000 nM	Non binder
T84631	Coagulation factor Xa	B8M4EP	5-Bromo-N-(4-guanidino-phenyl)-2-hydroxy-benzamide	Investigative	44303719	C14H13BrN4O2	349.18	C1=CC(=CC=C1NC(=O)C2=C(C=CC(=C2)Br)O)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	B8U7HR	20-Amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,13,18,20,22,27(30),28-nonaen-26-one	Investigative	134131303	C29H33N7O3	527.6	CC1=C2CNC(=O)C3=CN(CC4=C(C=C(C=C4)CN5C=CC=N5)OCCCC=CCCOC2=CC(=N1)N)N=C3	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B9CE6S	2-(6-Methyl-2-oxo-3-p-tolylmethanesulfonylamino-2H-pyridin-1-yl)-N-(4,5,6,7-tetrahydro-2H-indazol-5-ylmethyl)-acetamide	Investigative	44339404	C24H29N5O4S	483.6	CC1=CC=C(C=C1)CS(=O)(=O)NC2=CC=C(N(C2=O)CC(=O)NCC3CCC4=C(C3)C=NN4)C	Ki = 228000 nM	Non binder
T84631	Coagulation factor Xa	B9I3UR	(2S)-N-[(4-Aminocyclohexyl)methyl]-1-(3-phenyl-3-pyridin-4-ylpropanoyl)pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid	Investigative	44347477	C28H35F3N4O4	548.6	C1C[C@H](N(C1)C(=O)CC(C2=CC=CC=C2)C3=CC=NC=C3)C(=O)NCC4CCC(CC4)N.C(=O)(C(F)(F)F)O	Ki = 400000 nM	Non binder
T84631	Coagulation factor Xa	B9NR0F	N-(3-Amino-2-imino-2,3,4,5,6,7-hexahydro-benzothiazol-6-yl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide	Investigative	44339453	C22H26N6O4S2	502.6	CC1=CC=C(C(=O)N1CC(=O)NC2CCC3=C(C2)SC(=N)N3N)NS(=O)(=O)CC4=CC=CC=C4	Ki > 200000 nM	Non binder
T84631	Coagulation factor Xa	B9SG8F	[2-[(3,5-Dimethyl-1-phenylpyrazol-4-yl)amino]-2-oxoethyl] 2-phenylacetate	Investigative	16285203	C21H21N3O3	363.4	CC1=C(C(=NN1C2=CC=CC=C2)C)NC(=O)COC(=O)CC3=CC=CC=C3	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	B9U5JZ	N-[2-[(3-Fluorophenyl)methoxy]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide	Investigative	72712044	C24H24FN3O2	405.5	C1CN(CCC1C(=O)NC2=CC=CC=C2OCC3=CC(=CC=C3)F)C4=CC=NC=C4	Ki > 250000 nM	Non binder
T84631	Coagulation factor Xa	BBY1C6	4-Ethoxy-N-(4-guanidino-phenyl)-2-hydroxy-benzamide	Investigative	44303824	C16H18N4O3	314.34	CCOC1=CC(=C(C=C1)C(=O)NC2=CC=C(C=C2)N=C(N)N)O	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	BC7F8S	(2S)-2-Acetamido-N-[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide	Investigative	56676740	C34H42N6O4	598.7	CC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC3=CC=CC=C3	IC50 > 400000 nM	Non binder
T84631	Coagulation factor Xa	BCA2D3	Octasodium;[2-(3,4-disulfonatooxyphenyl)-5-[[4-[[2-(3,4-disulfonatooxyphenyl)-4-oxo-3,7-disulfonatooxychromen-5-yl]oxymethyl]phenyl]methoxy]-4-oxo-3-sulfonatooxychromen-7-yl] sulfate	Investigative	137647340	C38H18Na8O38S8	1523	C1=CC(=CC=C1COC2=CC(=CC3=C2C(=O)C(=C(O3)C4=CC(=C(C=C4)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])COC5=CC(=CC6=C5C(=O)C(=C(O6)C7=CC(=C(C=C7)OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-])OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]	IC50 = 505000 nM	Non binder
T84631	Coagulation factor Xa	BCAL64	3-Hydroxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304104	C22H18N4O2	370.4	C1=CC=C2C=C3C=C(C(=CC3=CC2=C1)C(=O)NC4=CC=C(C=C4)N=C(N)N)O	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	BDHP59	(2S)-N-[(6-Amino-2,4-dimethylpyridin-3-yl)methyl]-1-[(2R)-2-amino-3,3-diphenylpropanoyl]pyrrolidine-2-carboxamide	Investigative	10600484	C28H33N5O2	471.6	CC1=CC(=NC(=C1CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](C(C3=CC=CC=C3)C4=CC=CC=C4)N)C)N	Ki = 240000 nM	Non binder
T84631	Coagulation factor Xa	BDT8N3	Mangiferin heptasulfate	Investigative	53388478	C19H18O32S7	982.8	C1=C2C(=CC(=C1OS(=O)(=O)O)OS(=O)(=O)O)OC3=CC(=C(C(=C3C2=O)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)COS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O	IC50 = 970000 nM	Non binder
T84631	Coagulation factor Xa	BF0OM7	1-(3-Chlorobenzoyl)-6-methoxy-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one	Investigative	137635473	C27H24ClN3O4	489.9	COC1=CC2=C(C=C1)N(CN(C2=O)C3=CC=C(C=C3)N4CCCCC4=O)C(=O)C5=CC(=CC=C5)Cl	IC50 = 243000 nM	Non binder
T84631	Coagulation factor Xa	BF0ZS2	(S)-3-{[2-(4-Carbamimidoyl-benzyloxy)-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-7-carbonyl]-amino}-3-phenyl-propionic acid	Investigative	11489885	C27H26N4O6	502.5	CN1C2=C(C=C(C=C2)C(=O)N[C@@H](CC(=O)O)C3=CC=CC=C3)OC(C1=O)OCC4=CC=C(C=C4)C(=N)N	Ki > 200000 nM	Non binder
T84631	Coagulation factor Xa	BF4K6S	N-(4-Guanidino-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide	Investigative	44304100	C15H15IN4O2	410.21	CC1=CC(=C(C(=C1)I)O)C(=O)NC2=CC=C(C=C2)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	BFI20A	((R)-2-{(S)-2-[(6-Amino-pyridin-3-ylmethyl)-carbamoyl]-pyrrolidin-1-yl}-1-benzhydryl-2-oxo-ethyl)-carbamic acid tert-butyl ester	Investigative	10792619	C31H37N5O4	543.7	CC(C)(C)OC(=O)N[C@H](C(C1=CC=CC=C1)C2=CC=CC=C2)C(=O)N3CCC[C@H]3C(=O)NCC4=CN=C(C=C4)N	Ki > 200000 nM	Non binder
T84631	Coagulation factor Xa	BGCB48	alpha-Ketothiazole analogue 27	Investigative	16098905	C22H37N7O4S	495.6	CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)C1=NC=CS1)NC(=O)C	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BGD2R4	N-((R)-2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide	Investigative	11156015	C22H25N5O4S2	487.6	CC1=CC=C(C(=O)N1CC(=O)N[C@@H]2CCC3=C(C2)SC(=N3)N)NS(=O)(=O)CC4=CC=CC=C4	Ki = 225200 nM	Non binder
T84631	Coagulation factor Xa	BH02BU	Chembl4204525	Investigative	9881263	C13H11N3O2	241.24	CC1=CC=CC=C1C2=NC3=C(C=NN3C)C(=O)O2	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BH34BA	5-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]carbamoyl]-2-[2-[[4-(aminomethyl)phenyl]carbamoyl]-4-(methylamino)phenyl]benzoic acid	Investigative	16066741	C29H33N5O5	531.6	CC(C)C[C@@H](C(=O)N)NC(=O)C1=CC(=C(C=C1)C2=C(C=C(C=C2)NC)C(=O)NC3=CC=C(C=C3)CN)C(=O)O	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BH3J9L	3-Carbamimidoylbenzamide	Investigative	18327622	C8H9N3O	163.18	C1=CC(=CC(=C1)C(=O)N)C(=N)N	Ki = 250000 nM	Non binder
T84631	Coagulation factor Xa	BH9ZO7	Benzyl N-[(2R)-1-[[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate	Investigative	56676741	C40H46N6O5	690.8	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC2=CC=CC=C2)NC(=O)[C@@H](CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4	IC50 = 440000 nM	Non binder
T84631	Coagulation factor Xa	BHA23T	Chembl4218188	Investigative	9882885	C14H10FN3O2S	303.31	CCSC1=NC=C2C(=N1)N=C(OC2=O)C3=CC=CC=C3F	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BHQ75V	6-Methoxy-1-(3-methoxybenzoyl)-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one	Investigative	137641934	C28H27N3O5	485.5	COC1=CC2=C(C=C1)N(CN(C2=O)C3=CC=C(C=C3)N4CCCCC4=O)C(=O)C5=CC(=CC=C5)OC	IC50 = 354000 nM	Non binder
T84631	Coagulation factor Xa	BI5U3N	6-Amino-N-[(3S,7E,9S,12R,16S,19S)-16-[[3-(aminomethyl)phenyl]methyl]-12-[(2S)-butan-2-yl]-9-[(4-hydroxyphenyl)methyl]-2,6,11,14,18-pentaoxo-1,5,10,13,17-pentazabicyclo[17.3.0]docos-7-en-3-yl]hexanamide	Investigative	57392333	C42H60N8O7	789	CC[C@H](C)[C@@H]1C(=O)N[C@H](/C=C/C(=O)NC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](CC(=O)N1)CC3=CC(=CC=C3)CN)NC(=O)CCCCCN)CC4=CC=C(C=C4)O	Ki = 360000 nM	Non binder
T84631	Coagulation factor Xa	BJ5GN1	3-Chloro-N-(4-guanidino-phenyl)-2-hydroxy-benzamide	Investigative	44304192	C14H13ClN4O2	304.73	C1=CC(=C(C(=C1)Cl)O)C(=O)NC2=CC=C(C=C2)N=C(N)N	Ki = 470000 nM	Non binder
T84631	Coagulation factor Xa	BJM6H2	[1-[(Benzyloxycarbonyl)amino]-4-aminobutyl]phosphonic acid diphenyl ester	Investigative	10895700	C24H27N2O5P	454.5	C1=CC=C(C=C1)COC(=O)NC(CCCN)P(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3	IC50 > 250000 nM	Non binder
T84631	Coagulation factor Xa	BJOC38	N-[3-[(3-Fluorophenoxy)methyl]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide	Investigative	72712255	C24H24FN3O2	405.5	C1CN(CCC1C(=O)NC2=CC=CC(=C2)COC3=CC(=CC=C3)F)C4=CC=NC=C4	Ki > 250000 nM	Non binder
T84631	Coagulation factor Xa	BKRT84	2-[2-[(3-Carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]-5-[[(1S)-1-carboxy-3-methylbutyl]carbamoyl]benzoic acid	Investigative	44421837	C29H30N4O7	546.6	CC(C)C[C@@H](C(=O)O)NC(=O)C1=CC(=C(C=C1)C2=C(C=C(C=C2)NC)C(=O)NC3=CC=CC(=C3)C(=O)N)C(=O)O	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BL2TF5	alpha-Ketothiazole analogue 21	Investigative	16098899	C29H42Cl2N8O4S	669.7	CC(C)C[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)C1=NC=CS1)C(C)(C)C)NC(=O)NCC2=CC(=C(C=C2)Cl)Cl	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BL78EI	(3S)-2-[4-(4-Bromophenyl)thiophene-2-carbonyl]-N-methyl-N-[4-(3-oxomorpholin-4-yl)phenyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	Investigative	66573843	C32H28BrN3O4S	630.6	CN(C1=CC=C(C=C1)N2CCOCC2=O)C(=O)[C@@H]3CC4=CC=CC=C4CN3C(=O)C5=CC(=CS5)C6=CC=C(C=C6)Br	IC50 > 500000 nM	Non binder
T84631	Coagulation factor Xa	BLK85Y	Methyl 2-[(1R,3aS,8bS)-1-(5-amino-5-iminopentyl)-2-oxo-1,3a,4,8b-tetrahydroindeno[2,1-b]pyrrol-3-yl]acetate	Investigative	44290379	C19H25N3O3	343.4	COC(=O)CN1[C@H]2CC3=CC=CC=C3[C@@H]2[C@H](C1=O)CCCCC(=N)N	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BM85OU	Benzyl (3S)-3-[[4-(4-acetylpiperazin-1-yl)phenyl]carbamoyl]-3,4-dihydro-1H-isoquinoline-2-carboxylate	Investigative	66573912	C30H32N4O4	512.6	CC(=O)N1CCN(CC1)C2=CC=C(C=C2)NC(=O)[C@@H]3CC4=CC=CC=C4CN3C(=O)OCC5=CC=CC=C5	IC50 > 500000 nM	Non binder
T84631	Coagulation factor Xa	BMF60H	N-{3-[(4-Fluorobenzyl)oxy]-phenyl}piperidine-3-carboxamide	Investigative	25222774	C19H21FN2O2	328.4	C1CC(CNC1)C(=O)NC2=CC(=CC=C2)OCC3=CC=C(C=C3)F	Ki = 260000 nM	Non binder
T84631	Coagulation factor Xa	BN51TD	(3S)-2-[2-(3,4-Dimethoxyphenyl)acetyl]-N-methyl-N-[4-(2-oxopiperidin-1-yl)phenyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	Investigative	66573640	C32H35N3O5	541.6	CN(C1=CC=C(C=C1)N2CCCCC2=O)C(=O)[C@@H]3CC4=CC=CC=C4CN3C(=O)CC5=CC(=C(C=C5)OC)OC	IC50 = 246000 nM	Non binder
T84631	Coagulation factor Xa	BNFD34	Benzyl (3S)-3-[[4-[4-(thiophene-2-carbonyl)piperazin-1-yl]phenyl]carbamoyl]-3,4-dihydro-1H-isoquinoline-2-carboxylate	Investigative	66574033	C33H32N4O4S	580.7	C1CN(CCN1C2=CC=C(C=C2)NC(=O)[C@@H]3CC4=CC=CC=C4CN3C(=O)OCC5=CC=CC=C5)C(=O)C6=CC=CS6	IC50 > 500000 nM	Non binder
T84631	Coagulation factor Xa	BPD92J	N-(4-Guanidino-phenyl)-2-hydroxy-5-methyl-benzamide	Investigative	44303839	C15H16N4O2	284.31	CC1=CC(=C(C=C1)O)C(=O)NC2=CC=C(C=C2)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	BPI15N	Benzyl (3S)-3-[(4-chlorophenyl)carbamoyl]-3,4-dihydro-1H-isoquinoline-2-carboxylate	Investigative	66573909	C24H21ClN2O3	420.9	C1[C@H](N(CC2=CC=CC=C21)C(=O)OCC3=CC=CC=C3)C(=O)NC4=CC=C(C=C4)Cl	IC50 > 500000 nM	Non binder
T84631	Coagulation factor Xa	BPMC04	2-[4-[2-Diphenoxyphosphoryl-2-(methanesulfonamido)ethyl]phenyl]guanidine	Investigative	16718760	C22H25N4O5PS	488.5	CS(=O)(=O)NC(CC1=CC=C(C=C1)N=C(N)N)P(=O)(OC2=CC=CC=C2)OC3=CC=CC=C3	IC50 = 250000 nM	Non binder
T84631	Coagulation factor Xa	BPW2Q6	Chembl4211986	Investigative	16284785	C22H20N4O5	420.4	CC1=C(C(=NN1C2=CC=CC=C2)C)NC(=O)COC(=O)CN3C4=CC=CC=C4OC3=O	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BPXO13	(2S)-2-[[(2S)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-3-phenylpropanamide	Investigative	56673433	C39H46N6O5S	710.9	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=CC=C3)NS(=O)(=O)CC4=CC=CC=C4	IC50 > 590000 nM	Non binder
T84631	Coagulation factor Xa	BQ57NV	(13Z)-20-Amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,13,18,20,22,27(30),28-nonaen-26-one	Investigative	134131084	C29H33N7O3	527.6	CC1=C2CNC(=O)C3=CN(CC4=C(C=C(C=C4)CN5C=CC=N5)OCCC/C=C\\CCOC2=CC(=N1)N)N=C3	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BQ90LI	Sodium;[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl] sulfate	Investigative	53392251	C26H25NaO13S	600.5	CCOC(=O)C1=C(OC2=CC(=C(C=C21)OCC3=C(C4=CC(=C(C=C4O3)OC)OS(=O)(=O)[O-])C(=O)OCC)OC)C.[Na+]	IC50 > 300000 nM	Non binder
T84631	Coagulation factor Xa	BR1ZG9	2-Hydroxy-biphenyl-3-carboxylic acid (4-guanidino-phenyl)-amide	Investigative	44304105	C20H18N4O2	346.4	C1=CC=C(C=C1)C2=C(C(=CC=C2)C(=O)NC3=CC=C(C=C3)N=C(N)N)O	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	BR5VK9	Sodium;[2-[[6-methoxy-3-[(2-methylpropan-2-yl)oxycarbonyl]-1-benzofuran-5-yl]oxymethyl]-1,3-benzothiazol-6-yl] sulfate	Investigative	118723894	C22H20NNaO9S2	529.5	CC(C)(C)OC(=O)C1=COC2=CC(=C(C=C21)OCC3=NC4=C(S3)C=C(C=C4)OS(=O)(=O)[O-])OC.[Na+]	IC50 = 352000 nM	Non binder
T84631	Coagulation factor Xa	BRNU84	2-[6-Methyl-2-oxo-3-(3-trifluoromethyl-phenylmethanesulfonylamino)-2H-pyridin-1-yl]-N-(4,5,6,7-tetrahydro-2H-indazol-5-ylmethyl)-acetamide	Investigative	44339650	C24H26F3N5O4S	537.6	CC1=CC=C(C(=O)N1CC(=O)NCC2CCC3=C(C2)C=NN3)NS(=O)(=O)CC4=CC(=CC=C4)C(F)(F)F	Ki = 252000 nM	Non binder
T84631	Coagulation factor Xa	BRXD81	Diphenyl 1-(benzoylamino)-2-(4-guanidinophenyl)-ethanephosphonate	Investigative	16718807	C28H27N4O4P	514.5	C1=CC=C(C=C1)C(=O)NC(CC2=CC=C(C=C2)N=C(N)N)P(=O)(OC3=CC=CC=C3)OC4=CC=CC=C4	IC50 > 250000 nM	Non binder
T84631	Coagulation factor Xa	BS0Y6M	N-[3-[(3-Chlorophenyl)methoxy]phenyl]-1-pyridin-4-ylpiperidine-4-carboxamide	Investigative	72712055	C24H24ClN3O2	421.9	C1CN(CCC1C(=O)NC2=CC(=CC=C2)OCC3=CC(=CC=C3)Cl)C4=CC=NC=C4	Ki > 250000 nM	Non binder
T84631	Coagulation factor Xa	BSE39M	CGH-1484A free base	Investigative	9962561	C41H56FN7O6S2	826.1	CC1(CC2=C(C(=CC(=C2)CCC(=O)N3CCN(CC3)CC(=O)N4CCOCC4)S(=O)(=O)N[C@@H](CC5=NC6=CC=CC=C6S5)C(=O)N7CCC(CC7)CCF)NC1)C	Ki >= 200000 nM	Non binder
T84631	Coagulation factor Xa	BT2NL3	N-((S)-2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide	Investigative	44339610	C22H25N5O4S2	487.6	CC1=CC=C(C(=O)N1CC(=O)N[C@H]2CCC3=C(C2)SC(=N3)N)NS(=O)(=O)CC4=CC=CC=C4	Ki = 370600 nM	Non binder
T84631	Coagulation factor Xa	BT9P0N	2-[2-[(3-Carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]-5-(2-methylpropylcarbamoyl)benzoic acid	Investigative	44421826	C27H28N4O5	488.5	CC(C)CNC(=O)C1=CC(=C(C=C1)C2=C(C=C(C=C2)NC)C(=O)NC3=CC=CC(=C3)C(=O)N)C(=O)O	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BU3J0C	Chembl4212332	Investigative	41583852	C24H24N4O3	416.5	CC1=CC2=CC=CC=C2N1CC(=O)OCC(=O)NC3=C(N(N=C3C)C4=CC=CC=C4)C	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BV7UP5	1-Benzoyl-6-methoxy-3-[4-(2-oxopiperidin-1-yl)phenyl]-2H-quinazolin-4-one	Investigative	137633331	C27H25N3O4	455.5	COC1=CC2=C(C=C1)N(CN(C2=O)C3=CC=C(C=C3)N4CCCCC4=O)C(=O)C5=CC=CC=C5	IC50 = 546000 nM	Non binder
T84631	Coagulation factor Xa	BVB86M	(2S)-1-[(2R)-2-(Benzylsulfonylamino)-3-(3,4-dichlorophenyl)propanoyl]-N-(pyridin-4-ylmethyl)pyrrolidine-2-carboxamide	Investigative	10650805	C27H28Cl2N4O4S	575.5	C1C[C@H](N(C1)C(=O)[C@@H](CC2=CC(=C(C=C2)Cl)Cl)NS(=O)(=O)CC3=CC=CC=C3)C(=O)NCC4=CC=NC=C4	Ki > 200000 nM	Non binder
T84631	Coagulation factor Xa	BW27LG	(2S)-N-[(4-Aminocyclohexyl)methyl]-1-(3,3-dicyclohexylpropanoyl)pyrrolidine-2-carboxamide;hydrochloride	Investigative	45261772	C27H48ClN3O2	482.1	C1CCC(CC1)C(CC(=O)N2CCC[C@H]2C(=O)NCC3CCC(CC3)N)C4CCCCC4.Cl	Ki = 220000 nM	Non binder
T84631	Coagulation factor Xa	BX09PW	1-[5-(Diaminomethyl-amino)-2-(3-methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonylamino)-pentanoyl]-4-methyl-piperidine-2-carboxylic acid	Investigative	44386783	C23H36N6O5S	508.6	C[C@@H]1CCN(C(C1)C(=O)O)C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C	Ki = 210000 nM	Non binder
T84631	Coagulation factor Xa	BX0JP2	[(2S,3R,4S,5R,6R)-2-[9-Oxo-6-[(2S,3R,4S,5R,6R)-3,4,5-trisulfooxy-6-(sulfooxymethyl)oxan-2-yl]oxyxanthen-3-yl]oxy-3,5-disulfooxy-6-(sulfooxymethyl)oxan-4-yl] hydrogen sulfate	Investigative	71458531	C25H28O38S8	1193	C1=CC2=C(C=C1O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)OC4=C(C2=O)C=CC(=C4)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O	IC50 = 740000 nM	Non binder
T84631	Coagulation factor Xa	BX3D8N	N-((R)-2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-[3-(4-fluoro-phenylmethanesulfonylamino)-6-methyl-2-oxo-2H-pyridin-1-yl]-acetamide	Investigative	44339442	C22H24FN5O4S2	505.6	CC1=CC=C(C(=O)N1CC(=O)N[C@@H]2CCC3=C(C2)SC(=N3)N)NS(=O)(=O)CC4=CC=C(C=C4)F	Ki > 500000 nM	Non binder
T84631	Coagulation factor Xa	BX62VE	Benzyl N-[(2S)-1-[[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate	Investigative	56680052	C40H46N6O5	690.8	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCCN=C(N)N)C(=O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)OCC4=CC=CC=C4	IC50 = 508000 nM	Non binder
T84631	Coagulation factor Xa	BXD6U0	Tert-butyl (3S)-3-[methyl-[4-(2-oxopiperidin-1-yl)phenyl]carbamoyl]-3,4-dihydro-1H-isoquinoline-2-carboxylate	Investigative	66573469	C27H33N3O4	463.6	CC(C)(C)OC(=O)N1CC2=CC=CC=C2C[C@H]1C(=O)N(C)C3=CC=C(C=C3)N4CCCCC4=O	IC50 = 221000 nM	Non binder
T84631	Coagulation factor Xa	BXG6I0	2-(3,4-Dihydroxyphenyl)-5-[[4-[[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4-oxochromen-5-yl]oxymethyl]phenyl]methoxy]-3,7-dihydroxychromen-4-one	Investigative	137632528	C38H26O14	706.6	C1=CC(=CC=C1COC2=CC(=CC3=C2C(=O)C(=C(O3)C4=CC(=C(C=C4)O)O)O)O)COC5=CC(=CC6=C5C(=O)C(=C(O6)C7=CC(=C(C=C7)O)O)O)O	IC50 = 212000 nM	Non binder
T84631	Coagulation factor Xa	BY4Q7F	3-[3-(3-Benzyl-1H-indol-2-yl)-5-bromo-4-hydroxy-phenyl]-propionic acid	Investigative	44296078	C24H20BrNO3	450.3	C1=CC=C(C=C1)CC2=C(NC3=CC=CC=C32)C4=C(C(=CC(=C4)CCC(=O)O)Br)O	Ki = 300000 nM	Non binder
T84631	Coagulation factor Xa	BYKT87	(3S)-N-Methyl-2-(4-methylbenzoyl)-N-[4-(2-oxopiperidin-1-yl)phenyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide	Investigative	66573589	C30H31N3O3	481.6	CC1=CC=C(C=C1)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)N(C)C4=CC=C(C=C4)N5CCCCC5=O	IC50 = 209000 nM	Non binder
T84631	Coagulation factor Xa	BZ79PQ	alpha-Ketothiazole analogue 18	Investigative	16098896	C31H44Cl2N8O4S	695.7	CC(C)C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)C2=NC=CS2)NC(=O)NCC3=CC(=C(C=C3)Cl)Cl	IC50 > 200000 nM	Non binder
T84631	Coagulation factor Xa	BZ8S9M	(2S)-1-[(2R)-2-(Benzylsulfonylamino)-3-(3,4-dichlorophenyl)propanoyl]-N-(pyridin-3-ylmethyl)pyrrolidine-2-carboxamide	Investigative	10698376	C27H28Cl2N4O4S	575.5	C1C[C@H](N(C1)C(=O)[C@@H](CC2=CC(=C(C=C2)Cl)Cl)NS(=O)(=O)CC3=CC=CC=C3)C(=O)NCC4=CN=CC=C4	Ki = 230000 nM	Non binder
T84631	Coagulation factor Xa	BZSH38	N-(4-Guanidino-phenyl)-2-hydroxy-5-nitro-benzamide	Investigative	44303721	C14H13N5O4	315.28	C1=CC(=CC=C1NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])O)N=C(N)N	Ki > 470000 nM	Non binder
T84631	Coagulation factor Xa	BZYL38	(8e)-3-Amino-1-Methyl-15-[(1h-Pyrazol-1-Yl)methyl]-7,10,11,12,24,25-Hexahydro-6h,18h,23h-19,22-(Metheno)pyrido[4,3-J][1,9,13,17,18]benzodioxatriazacyclohenicosin-23-One	Investigative	134131589	C29H33N7O3	527.6	CC1=C2CNC(=O)C3=CN(CC4=C(C=C(C=C4)CN5C=CC=N5)OCCC/C=C/CCOC2=CC(=N1)N)N=C3	IC50 > 200000 nM	Non binder