TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T87675	Aurora kinase A	D0R6TI	Inamrinone Lactate	Approved	3698	C10H9N3O	187.2	C1=CN=CC=C1C2=CNC(=O)C(=C2)N	Ki = 393900 nM	Non binder
T87675	Aurora kinase A	D0A3MV	AR-A014418	Patented	448014	C12H12N4O4S	308.32	COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]	IC50 > 100000000 nM	Non binder
T87675	Aurora kinase A	B0XKW1	1-[(4-Methoxyphenyl)methyl]-3-[6-(2H-tetrazol-5-yl)-1,3-benzothiazol-2-yl]urea	Investigative	53388145	C17H15N7O2S	381.4	COC1=CC=C(C=C1)CNC(=O)NC2=NC3=C(S2)C=C(C=C3)C4=NNN=N4	IC50 = 4800000 nM	Non binder
T87675	Aurora kinase A	B1LD6H	N-[3-[3-[[2-Methyl-6-(2-morpholin-4-ylethylamino)pyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide	Investigative	56676922	C26H30N8O3S	534.6	CC1=NC(=CC(=N1)NC2=NNC(=C2)C3=CC(=CC=C3)NS(=O)(=O)C4=CC=CC=C4)NCCN5CCOCC5	IC50 > 1000000 nM	Non binder
T87675	Aurora kinase A	B5N7CM	(3S,6S,9S,15S,21R,26R,29S)-21-Amino-N-(2-amino-2-oxoethyl)-6-(3-amino-3-oxopropyl)-15-(1H-imidazol-5-ylmethyl)-2,5,8,14,17,20,28-heptaoxo-3-propan-2-yl-23,24-dithia-1,4,7,13,16,19,27-heptazatricyclo[27.3.0.09,13]dotriacontane-26-carboxamide	Investigative	57401650	C36H55N13O10S2	894	CC(C)[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N3CCC[C@H]3C(=O)N[C@H](C(=O)N1)CCC(=O)N)CC4=CN=CN4)N)C(=O)NCC(=O)N	IC50 = 234000 nM	Non binder
T87675	Aurora kinase A	B67SWV	2-[(3S,9S,12R,17R,20S,23S,26S)-12-Amino-17-[(2-amino-2-oxoethyl)carbamoyl]-20-(1H-imidazol-5-ylmethyl)-23-(1H-indol-3-ylmethyl)-2,5,8,11,19,22,25-heptaoxo-3-propan-2-yl-14,15-dithia-1,4,7,10,18,21,24-heptazabicyclo[24.3.0]nonacosan-9-yl]acetic acid	Investigative	57399870	C41H55N13O11S2	970.1	CC(C)[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N1)CC(=O)O)N)C(=O)NCC(=O)N)CC3=CN=CN3)CC4=CNC5=CC=CC=C54	IC50 = 242000 nM	Non binder
T87675	Aurora kinase A	B6L2UT	3-Amino-2-hydroxypyridine	Investigative	322353	C5H6N2O	110.11	C1=CNC(=O)C(=C1)N	Ki = 361000 nM	Non binder
T87675	Aurora kinase A	B7X9IN	3-(1H-Benzimidazol-2-yl)-6-chloro-1H-benzimidazol-2-one	Investigative	134143409	C14H9ClN4O	284.7	C1=CC=C2C(=C1)NC(=N2)N3C4=C(C=C(C=C4)Cl)NC3=O	IC50 > 200000 nM	Non binder
T87675	Aurora kinase A	BEP1H3	1-[(4-Methoxyphenyl)methyl]-3-[4-(2H-tetrazol-5-yl)pyridin-2-yl]urea	Investigative	53388146	C15H15N7O2	325.33	COC1=CC=C(C=C1)CNC(=O)NC2=NC=CC(=C2)C3=NNN=N3	IC50 > 100000000 nM	Non binder
T87675	Aurora kinase A	BGWS79	N-[3-[3-[[6-[2-(Dimethylamino)ethylamino]-2-methylpyrimidin-4-yl]amino]-1H-pyrazol-5-yl]phenyl]benzenesulfonamide	Investigative	56683569	C24H28N8O2S	492.6	CC1=NC(=CC(=N1)NC2=NNC(=C2)C3=CC(=CC=C3)NS(=O)(=O)C4=CC=CC=C4)NCCN(C)C	IC50 > 1000000 nM	Non binder
T87675	Aurora kinase A	BGZ7Q5	CID 56659825	Investigative	56659825	C23H32N8O2S	484.6	CCCCS(=O)(=O)NC1=CC=CC(=C1)C2=CC(=NN2)NC3=CC(=NC(=N3)C)N4CCN(CC4)C	IC50 > 1000000 nM	Non binder
T87675	Aurora kinase A	BJ57YZ	N-(4-Methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine	Investigative	50908681	C19H16N2O2	304.3	COC1=CC=C(C=C1)CNC2=C3C4=CC=CC=C4OC3=NC=C2	Ki > 1000000 nM	Non binder
T87675	Aurora kinase A	BQL98K	1-(4-Cyanopyridin-2-yl)-3-[(4-methoxyphenyl)methyl]urea	Investigative	56675716	C15H14N4O2	282.3	COC1=CC=C(C=C1)CNC(=O)NC2=NC=CC(=C2)C#N	IC50 > 100000000 nM	Non binder
T87675	Aurora kinase A	BSC95P	CID 56676977	Investigative	56676977	C26H30N8O2S	518.6	CC1=CC(=CC=C1)S(=O)(=O)NC2=CC=CC(=C2)C3=CC(=NN3)NC4=CC(=NC(=N4)C)N5CCN(CC5)C	IC50 > 1000000 nM	Non binder
T87675	Aurora kinase A	BSZ98H	1-[(4-Methoxyphenyl)methyl]-3-(6-nitro-1,3-benzothiazol-2-yl)urea	Investigative	56668847	C16H14N4O4S	358.4	COC1=CC=C(C=C1)CNC(=O)NC2=NC3=C(S2)C=C(C=C3)[N+](=O)[O-]	IC50 > 100000000 nM	Non binder
T87675	Aurora kinase A	BZJ8O3	(5Z)-3-(Cyclohexylmethyl)-2-(4-ethylphenyl)imino-5-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one	Investigative	134153888	C24H27N3OS	405.6	CCC1=CC=C(C=C1)N=C2N(C(=O)/C(=C/C3=CC=NC=C3)/S2)CC4CCCCC4	IC50 > 200000 nM	Non binder