TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T88806	Integrin alpha-5/beta-1	D0BN9X	Tirofiban	Approved	60947	C22H36N2O5S	440.6	CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCC2CCNCC2)C(=O)O	IC50 > 300000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B3MA8R	4-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)amino)-4-oxobutanoic acid	Investigative	44436710	C27H32N4O4	476.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)CCC(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B3RN5S	2-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)carbamoyl)-4-methoxy-4-oxobutanoic acid	Investigative	44436711	C29H34N4O6	534.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)C(CC(=O)OC)C(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B42MKT	2-({1-[(4-Aminophenyl)methyl]-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl}(propyl)carbamoyl)butanedioic acid	Investigative	44436715	C27H31N3O6	493.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)N)C3=CC=CC=C3)C)C(=O)C(CC(=O)O)C(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B4A2OQ	3-(3-(3-Amino-N-propylpropanamido)-4-methyl-2-oxo-6-phenyl-5,6-dihydropyridin-1(2H)-yl)propanoic acid	Investigative	44436701	C21H29N3O4	387.5	CCCN(C1=C(CC(N(C1=O)CCC(=O)O)C2=CC=CC=C2)C)C(=O)CCN	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B52DWA	(S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-propyl)-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetyl}-amino)-acetylamino]-propionic acid	Investigative	9852055	C33H40N4O8	620.7	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N(CCCOC)CC(=O)N[C@@H](CC(=O)O)C3=CC(=C(C=C3)OC)OC	IC50 > 500000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B5FA7L	3-(3-(6-Amino-N-propylhexanamido)-4-methyl-2-oxo-6-phenyl-5,6-dihydropyridin-1(2H)-yl)propanoic acid	Investigative	44436703	C24H35N3O4	429.6	CCCN(C1=C(CC(N(C1=O)CCC(=O)O)C2=CC=CC=C2)C)C(=O)CCCCCN	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B5Z6FV	Arginyl-glycyl-aspartic acid	Investigative	104802	C12H22N6O6	346.34	C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O)N)CN=C(N)N	IC50 = 830000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B63UPD	H-Vyavtgrgdspa-NH2	Investigative	44320508	C51H82N16O17	1191.3	C[C@H]([C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](C)C(=O)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](C(C)C)N)O	IC50 = 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B7I2LJ	(R)-3-[(R)-5-(3-Guanidino-propylcarbamoyl)-2-oxo-1-aza-bicyclo[5.2.0]non-8-yl]-propionic acid	Investigative	44286634	C16H27N5O4	353.42	C1CC(=O)N2C[C@@H]([C@H]2C[C@@H]1C(=O)NCCCN=C(N)N)CCC(=O)O	IC50 = 3100000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B7NE3U	2-({1-[(4-Aminophenyl)methyl]-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl}(propyl)carbamoyl)-4-methoxy-4-oxobutanoic acid	Investigative	44436714	C28H33N3O6	507.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)N)C3=CC=CC=C3)C)C(=O)C(CC(=O)OC)C(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B7XH2C	(S)-3-(4-Methoxy-phenyl)-3-[2-((3-methoxy-propyl)-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetyl}-amino)-acetylamino]-propionic acid	Investigative	9808598	C32H38N4O7	590.7	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N(CCCOC)CC(=O)N[C@@H](CC(=O)O)C3=CC=C(C=C3)OC	IC50 > 500000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B90CFS	N-(2,6-Dichlorobenzoyl)-3-[2-(pyridin-2-ylamino)ethoxy]-L-phenylalanine	Investigative	59665282	C23H21Cl2N3O4	474.3	C1=CC=NC(=C1)NCCOC2=CC=CC(=C2)C[C@@H](C(=O)O)NC(=O)C3=C(C=CC=C3Cl)Cl	IC50 > 290000 nM	Non binder
T88806	Integrin alpha-5/beta-1	B9S3TX	3-(((S)-6-(4-Aminophenyl)-1-((S)-1-(4-methoxyphenyl)ethyl)-4-methyl-2-oxo-1,2,5,6-tetrahydropyridin-3-yl)(propyl)amino)-3-oxopropanoic acid	Investigative	44436705	C27H33N3O5	479.6	CCCN(C1=C(C[C@H](N(C1=O)[C@@H](C)C2=CC=C(C=C2)OC)C3=CC=C(C=C3)N)C)C(=O)CC(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BAZ2O1	N-{6-(4-Carbamimidoyl-phenyl)-1-[(S)-1-(4-methoxy-phenyl)-ethyl]-4-methyl-2-oxo-1,2,5,6-tetrahydro-pyridin-3-yl}-N-propyl-malonamic acid	Investigative	44436708	C28H34N4O5	506.6	CCCN(C1=C(CC(N(C1=O)[C@@H](C)C2=CC=C(C=C2)OC)C3=CC=C(C=C3)C(=N)N)C)C(=O)CC(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BB1F4V	(S)-3-[2-((3-Methoxy-propyl)-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetyl}-amino)-acetylamino]-3-phenyl-propionic acid	Investigative	9807891	C31H36N4O6	560.6	CC1=CC=CC=C1NC(=O)NC2=CC=C(C=C2)CC(=O)N(CCCOC)CC(=O)N[C@@H](CC(=O)O)C3=CC=CC=C3	IC50 > 500000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BF5J6Z	(S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amino]-3-[4-(2,6-dichloro-benzyloxy)-phenyl]-propionic acid	Investigative	9870468	C22H22Cl2N2O5S	497.4	CC(=O)N1CSC[C@@H]1C(=O)N[C@@H](CC2=CC=C(C=C2)OCC3=C(C=CC=C3Cl)Cl)C(=O)O	IC50 > 800000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BJ5I9G	3-[4-(6-Amino-hexyloxy)-phenyl]-2-(butane-1-sulfonylamino)-propionic acid	Investigative	10069591	C19H32N2O5S	400.5	CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCCCN)C(=O)O	IC50 > 500000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BL49GD	3-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)amino)-3-oxopropanoic acid	Investigative	44436709	C26H30N4O4	462.5	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)CC(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BMR60P	2-((1-(4-Carbamimidoylbenzyl)-4-methyl-2-oxo-6-phenyl-1,2,5,6-tetrahydropyridin-3-yl)(propyl)carbamoyl)succinic acid	Investigative	44436712	C28H32N4O6	520.6	CCCN(C1=C(CC(N(C1=O)CC2=CC=C(C=C2)C(=N)N)C3=CC=CC=C3)C)C(=O)C(CC(=O)O)C(=O)O	IC50 > 1000000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BN4YW7	(E)-(S)-3-[2-((3-Methoxy-propyl)-{2-[4-(3-o-tolyl-ureido)-phenyl]-acetyl}-amino)-acetylamino]-hex-4-enoic acid	Investigative	9849697	C28H36N4O6	524.6	C/C=C/[C@H](CC(=O)O)NC(=O)CN(CCCOC)C(=O)CC1=CC=C(C=C1)NC(=O)NC2=CC=CC=C2C	IC50 > 500000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BOT78C	3-[5-(3-Guanidino-propylcarbamoyl)-2-oxo-1-aza-bicyclo[5.2.0]non-8-yl]-propionic acid	Investigative	11024622	C16H27N5O4	353.42	C1CC(=O)N2CC(C2CC1C(=O)NCCCN=C(N)N)CCC(=O)O	IC50 = 1300000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BUKP90	(3S)-3-[[2-[[(2S)-2-[[2-[[(2S,3R)-2-[[(2S)-2-Amino-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxyethyl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid	Investigative	9919094	C34H58N12O14	858.9	C[C@H]([C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](C(C)C)N)O	IC50 = 1100000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BW65BG	3-[4-(7-Amino-heptyloxy)-phenyl]-2-benzyloxycarbonylamino-propionic acid	Investigative	10455265	C24H32N2O5	428.5	C1=CC=C(C=C1)COC(=O)N[C@@H](CC2=CC=C(C=C2)OCCCCCCCN)C(=O)O	IC50 > 450000 nM	Non binder
T88806	Integrin alpha-5/beta-1	BWD4J9	Arginyl-glycyl-aspartyl-phenylalanine	Investigative	3080994	C21H31N7O7	493.5	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)N	IC50 = 1546000 nM	Non binder
T88806	Integrin alpha-5/beta-1	D01AXA	Ac-Asp-Arg-Leu-Asp-Ser-OH	Investigative	11764797	C25H42N8O12	646.6	CC(C)C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)NC(=O)C	IC50 = 259000 nM	Non binder