TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T94912	HUMAN C5a receptor	B28RPC	2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-6-amino-hexanoylamino}-3-carboxy-propionylamino)-3-phenyl-propionylamino]-3-phenyl-propionylamino}-3-phenyl-propionylamino)-propionylamino]-5-guanidino-pentanoic acid	Investigative	15725949	C54H72N14O12	1109.2	C[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC4=CN=CN4)NC(=O)C	Ki = 750000 nM	Non binder
T94912	HUMAN C5a receptor	B61HMS	2-[2-(2-{2-[2-(2-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-6-amino-hexanoylamino}-3-carboxy-propionylamino)-3-cyclohexyl-propionylamino]-3-cyclohexyl-propionylamino}-pentanoylamino)-propionylamino]-5-guanidino-pentanoic acid	Investigative	118719096	C51H86N14O12	1087.3	C[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC1CCCCC1)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@H](CC(=O)O)NC(=O)C(CCCCN)NC(=O)[C@H](CC3=CN=CN3)NC(=O)C	Ki = 600000 nM	Non binder
T94912	HUMAN C5a receptor	B6FDW4	Tyr-Ser-Phe-Lys-Asp-Ala-Pro-Leu-Gly-Arg	Investigative	10011515	C53H80N14O15	1153.3	C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	EC50 = 207000 nM	Non binder
T94912	HUMAN C5a receptor	B6K8PW	Tyr-Ser-Phe-Lys-Asp-Met-Pro-Ala-Gly-Arg	Investigative	10418799	C52H78N14O15S	1171.3	C[C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	EC50 = 215000 nM	Non binder
T94912	HUMAN C5a receptor	BBL9D5	Tyr-Ser-Phe-Lys-Asp-Met-Gln-Leu-Ala-Arg	Investigative	9989013	C56H87N15O16S	1258.4	C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC2=CC=C(C=C2)O)N	EC50 = 1000000 nM	Non binder
T94912	HUMAN C5a receptor	BBZY63	Tyr-Ser-Phe-Lys-Asp-Met-Gln-Leu-Pro-Arg	Investigative	10464120	C58H89N15O16S	1284.5	CC(C)C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	EC50 = 500000 nM	Non binder
T94912	HUMAN C5a receptor	BEH47Q	Ishkdmqlgr	Investigative	44305325	C49H85N17O15S	1184.4	CC[C@H](C)[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N	Ki = 300000 nM	Non binder
T94912	HUMAN C5a receptor	BL0MN2	(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoyl]amino]-3-carboxypropanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoic acid	Investigative	15725946	C44H76N14O12	993.2	CCCC[C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCCC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=CN=CN1)NC(=O)C	Ki = 210000 nM	Non binder
T94912	HUMAN C5a receptor	BO0A5M	Tyr-Ser-Phe-Lys-Asp-Cys-Pro-Leu-Cys-Arg	Investigative	10260801	C54H82N14O15S2	1231.4	CC(C)C[C@@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	EC50 = 224000 nM	Non binder
T94912	HUMAN C5a receptor	BQI20Z	Tyr-Ser-Phe-Lys-Asp-Cys-Pro-Leu-Gly-Arg	Investigative	10418817	C53H80N14O15S	1185.4	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	EC50 > 1000000 nM	Non binder
T94912	HUMAN C5a receptor	BRM9Y4	Tyr-Ser-Phe-Lys-Asp-Met-Pro-Ala-D-Ala-Arg	Investigative	10374110	C53H80N14O15S	1185.4	C[C@@H](C(=O)N[C@H](C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CC=C(C=C3)O)N	EC50 > 1000000 nM	Non binder
T94912	HUMAN C5a receptor	BSD36N	L-Ala-L-Lys-L-Pro-3-Cyclohexyl-D-Ala-L-Trp-D-Arg-OH	Investigative	10819181	C40H63N11O7	810	C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC2CCCCC2)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CCCN=C(N)N)C(=O)O)N	IC50 > 1000000 nM	Non binder
T94912	HUMAN C5a receptor	BT6MP5	H-His-Lys-AspMet-GIn-Leu-Gly-Arg-OH	Investigative	44305324	C40H69N15O12S	984.1	CC(C)C[C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=CN=CN1)N	Ki = 300000 nM	Non binder
T94912	HUMAN C5a receptor	BYJ1E9	Tyr-Ser-Phe-Lys-Asp-cyclo[Cys-Pro-Leu-Cys]-Arg	Investigative	44347020	C54H80N14O15S2	1229.4	CC(C)C[C@H]1C(=O)N[C@@H](CSSC[C@H](C(=O)N2CCC[C@@H]2C(=O)N1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CO)NC(=O)[C@H](CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O	EC50 = 500000 nM	Non binder