TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T95913	PI3-kinase gamma	D0DF2M	PMID28870136-Compound-48	Patented	2153	C7H8N4O2	180.16	CN1C2=C(C(=O)N(C1=O)C)NC=N2	IC50 = 800000 nM	Non binder
T95913	PI3-kinase gamma	D0H9IX	PMID28870136-Compound-52	Patented	2519	C8H10N4O2	194.19	CN1C=NC2=C1C(=O)N(C(=O)N2C)C	IC50 = 1000000 nM	Non binder
T95913	PI3-kinase gamma	B0PFB2	3-[4-(Benzyloxy)-3-methoxyphenyl]pentanedioic acid	Investigative	347279	C19H20O6	344.4	COC1=C(C=CC(=C1)C(CC(=O)O)CC(=O)O)OCC2=CC=CC=C2	IC50 = 5876000 nM	Non binder
T95913	PI3-kinase gamma	B43MQP	2-(7-Oxobenzo[a]phenalen-3-yl)sulfinylacetic acid	Investigative	226105	C19H12O4S	336.4	C1=CC=C2C(=C1)C3=C4C(=C(C=C3)S(=O)CC(=O)O)C=CC=C4C2=O	IC50 = 1570000 nM	Non binder
T95913	PI3-kinase gamma	B4Y2SQ	3-Butyl-2-(7H-purin-6-ylsulfanylmethyl)quinazolin-4-one	Investigative	9925404	C18H18N6OS	366.4	CCCCN1C(=NC2=CC=CC=C2C1=O)CSC3=NC=NC4=C3NC=N4	IC50 = 217800 nM	Non binder
T95913	PI3-kinase gamma	B4ZEF0	2-Methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile	Investigative	14501859	C8H6N4	158.16	CC1=NN2C=CC=NC2=C1C#N	IC50 = 773000 nM	Non binder
T95913	PI3-kinase gamma	B5KQP3	5-Chloro-2-[2-[3-[(3-fluorosulfonylphenyl)carbamoylamino]anilino]-2-oxoethoxy]benzoic acid	Investigative	309591	C22H17ClFN3O7S	521.9	C1=CC(=CC(=C1)NC(=O)NC2=CC(=CC=C2)S(=O)(=O)F)NC(=O)COC3=C(C=C(C=C3)Cl)C(=O)O	IC50 = 9157000 nM	Non binder
T95913	PI3-kinase gamma	B6MY5D	7-(4-Ethoxyanilino)-4-hydroxynaphthalene-2-sulfonic acid	Investigative	235602	C18H17NO5S	359.4	CCOC1=CC=C(C=C1)NC2=CC3=CC(=CC(=C3C=C2)O)S(=O)(=O)O	IC50 = 992000 nM	Non binder
T95913	PI3-kinase gamma	B7LB5F	2-Propan-2-ylpyrazolo[1,5-a]pyrimidine-3-carbonitrile	Investigative	57401565	C10H10N4	186.21	CC(C)C1=NN2C=CC=NC2=C1C#N	IC50 = 395000 nM	Non binder
T95913	PI3-kinase gamma	B8SKH9	11-(4-Methoxyphenyl)-13-morpholin-4-yl-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180796	C26H27N5O2S	473.6	COC1=CC=C(C=C1)C2=NC(=C3C4CCCN4C(=S)N(C3=N2)C5=CC=CC=C5)N6CCOCC6	IC50 = 345900 nM	Non binder
T95913	PI3-kinase gamma	B9AG6R	5,7-Dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-amine	Investigative	267310	C7H9N5	163.18	CC1=CC(=NC2=NC(=NN12)N)C	IC50 > 1600000 nM	Non binder
T95913	PI3-kinase gamma	B9BZ6N	3-(3,4-Dimethoxyphenyl)-3-(3,4,5-trimethoxyphenyl)propanoic acid	Investigative	270557	C20H24O7	376.4	COC1=C(C=C(C=C1)C(CC(=O)O)C2=CC(=C(C(=C2)OC)OC)OC)OC	IC50 = 6074000 nM	Non binder
T95913	PI3-kinase gamma	BB31WX	5-(2-Chlorophenylazo)-6-hydroxy-2-naphthalenesulfonic acid	Investigative	79972	C16H11ClN2O4S	362.8	C1=CC=C(C(=C1)N=NC2=C(C=CC3=C2C=CC(=C3)S(=O)(=O)O)O)Cl	IC50 = 1498000 nM	Non binder
T95913	PI3-kinase gamma	BBA1V6	2-Amino-6-chlorobenzoxazole	Investigative	40237	C7H5ClN2O	168.58	C1=CC2=C(C=C1Cl)OC(=N2)N	IC50 = 380000 nM	Non binder
T95913	PI3-kinase gamma	BC8KQ1	6-(6-Methoxynaphthalen-2-yl)-2-methyl-6-oxohexanoic acid	Investigative	247414	C18H20O4	300.3	CC(CCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O	IC50 = 5184000 nM	Non binder
T95913	PI3-kinase gamma	BCV2S9	4-{5-Oxo-3-pentadecyl-4-[(e)-phenyldiazenyl]-4,5-dihydro-1h-pyrazol-1-yl}benzenesulfonic acid	Investigative	274101	C30H42N4O4S	554.7	CCCCCCCCCCCCCCCC1=NN(C(=O)C1N=NC2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)O	IC50 = 241000 nM	Non binder
T95913	PI3-kinase gamma	BF3U6P	(2S)-4-(1,3-Benzodioxol-5-yl)-4-oxo-2-[(3,4,5-trimethoxyphenyl)methyl]butanoic acid	Investigative	92172785	C21H22O8	402.4	COC1=CC(=CC(=C1OC)OC)C[C@@H](CC(=O)C2=CC3=C(C=C2)OCO3)C(=O)O	IC50 = 575000 nM	Non binder
T95913	PI3-kinase gamma	BGUS85	11-(3-Methoxyphenyl)-13-morpholin-4-yl-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180795	C26H27N5O2S	473.6	COC1=CC=CC(=C1)C2=NC(=C3C4CCCN4C(=S)N(C3=N2)C5=CC=CC=C5)N6CCOCC6	IC50 = 465500 nM	Non binder
T95913	PI3-kinase gamma	BIUS43	{2-[(3-Ethyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-4-nitrophenoxy}acetic acid	Investigative	6053578	C14H12N2O6S2	368.4	CCN1C(=O)/C(=C\\C2=C(C=CC(=C2)[N+](=O)[O-])OCC(=O)O)/SC1=S	IC50 = 612000 nM	Non binder
T95913	PI3-kinase gamma	BO0WH3	7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine	Investigative	520127	C6H5ClN4	168.58	CC1=NC2=NC=NN2C(=C1)Cl	IC50 > 1670000 nM	Non binder
T95913	PI3-kinase gamma	BO5C4T	3-(2,3,10,11-Tetramethoxyisoquinolino[2,1-b]isoquinolin-7-ium-8-yl)propanoic acid	Investigative	426449	C24H24NO6+	422.4	COC1=CC2=CC3=[N+](C=CC4=CC(=C(C=C43)OC)OC)C(=C2C=C1OC)CCC(=O)O	IC50 = 7333000 nM	Non binder
T95913	PI3-kinase gamma	BQ2BT1	13-Morpholin-4-yl-11-(morpholin-4-ylmethyl)-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180839	C24H30N6O2S	466.6	C1CC2C3=C(N=C(N=C3N(C(=S)N2C1)C4=CC=CC=C4)CN5CCOCC5)N6CCOCC6	IC50 = 781500 nM	Non binder
T95913	PI3-kinase gamma	BTI9F4	4-[(4-Carboxy-2,5-dimethyl-phenyl)disulfanyl]-2,5-dimethyl-benzoic acid	Investigative	275065	C18H18O4S2	362.5	CC1=CC(=C(C=C1SSC2=CC(=C(C=C2C)C(=O)O)C)C)C(=O)O	IC50 = 1460000 nM	Non binder
T95913	PI3-kinase gamma	BV56MY	6-Hydroxy-5-[[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]diazenyl]naphthalene-2-sulfonic acid	Investigative	165595	C24H20N4O4S	460.5	CC1=CC=CC=C1N=NC2=CC(=C(C=C2)N=NC3=C(C=CC4=C3C=CC(=C4)S(=O)(=O)O)O)C	IC50 = 2415000 nM	Non binder
T95913	PI3-kinase gamma	BW59KC	6-Hydroxy-5-[[2-methoxy-4-[(4-sulfophenyl)diazenyl]phenyl]diazenyl]naphthalene-2-sulfonic acid	Investigative	414938	C23H18N4O8S2	542.5	COC1=C(C=CC(=C1)N=NC2=CC=C(C=C2)S(=O)(=O)O)N=NC3=C(C=CC4=C3C=CC(=C4)S(=O)(=O)O)O	IC50 = 2437000 nM	Non binder
T95913	PI3-kinase gamma	BWL19S	5,7-Dimethylpyrazolo[1,5-a]pyrimidin-2-amine	Investigative	28063903	C8H10N4	162.19	CC1=CC(=NC2=CC(=NN12)N)C	IC50 = 915000 nM	Non binder
T95913	PI3-kinase gamma	BY0J9C	4-(1,3-Benzodioxol-5-yl)-2-(3,4-dimethoxyphenyl)-4-oxobutanoic acid	Investigative	291727	C19H18O7	358.3	COC1=C(C=C(C=C1)C(CC(=O)C2=CC3=C(C=C2)OCO3)C(=O)O)OC	IC50 = 234000 nM	Non binder
T95913	PI3-kinase gamma	BZ42BQ	13-Morpholin-4-yl-11-(1-morpholin-4-ylethyl)-8-phenyl-6,8,10,12-tetrazatricyclo[7.4.0.02,6]trideca-1(13),9,11-triene-7-thione	Investigative	122180840	C25H32N6O2S	480.6	CC(C1=NC(=C2C3CCCN3C(=S)N(C2=N1)C4=CC=CC=C4)N5CCOCC5)N6CCOCC6	IC50 = 967700 nM	Non binder
T95913	PI3-kinase gamma	BZ7O3R	n,o-Bis[(benzyloxy)carbonyl]tyrosine	Investigative	263480	C25H23NO7	449.5	C1=CC=C(C=C1)COC(=O)NC(CC2=CC=C(C=C2)OC(=O)OCC3=CC=CC=C3)C(=O)O	IC50 = 324000 nM	Non binder
T95913	PI3-kinase gamma	D09ZNV	CGP-029482	Investigative	447682	C17H12N2O3	292.29	C1=CC=C2C(=C1)C(=C3N2C4=CC=CC=C4C(=O)N3)CC(=O)O	IC50 > 200000 nM	Non binder