TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T95947 Acid-sensing ion channel 3 B68AOD 2-(3-Fluoro-5-methoxyphenyl)-1H-indole-5-carboximidamide Investigative 25254510 C16H14FN3O 283.3 COC1=CC(=CC(=C1)C2=CC3=C(N2)C=CC(=C3)C(=N)N)F IC50 = 374000 nM Non binder T95947 Acid-sensing ion channel 3 B6EWG9 6-Bromo-1,2,3,4-tetrahydroisoquinoline Investigative 15885183 C9H10BrN 212.09 C1CNCC2=C1C=C(C=C2)Br IC50 = 701000 nM Non binder T95947 Acid-sensing ion channel 3 BBVN80 4-(1H-Imidazol-4-yl)aniline Investigative 910176 C9H9N3 159.19 C1=CC(=CC=C1C2=CN=CN2)N IC50 = 430000 nM Non binder T95947 Acid-sensing ion channel 3 BCRI16 2-(3-Chloro-5-fluorophenyl)-1H-indole-5-carboximidamide Investigative 45268406 C15H11ClFN3 287.72 C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=CC(=CC(=C3)Cl)F IC50 = 278000 nM Non binder T95947 Acid-sensing ion channel 3 BHY30B 2-(3,5-Dichloro-4-cyanophenyl)-1H-indole-5-carboximidamide Investigative 45272657 C16H10Cl2N4 329.2 C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=CC(=C(C(=C3)Cl)C#N)Cl IC50 = 272000 nM Non binder T95947 Acid-sensing ion channel 3 BIWO74 2-Phenyl-1H-indole-5-carboximidamide Investigative 44276630 C15H13N3 235.28 C1=CC=C(C=C1)C2=CC3=C(N2)C=CC(=C3)C(=N)N IC50 = 2765000 nM Non binder T95947 Acid-sensing ion channel 3 BM6ST1 2-(2,6-Dichloropyridin-4-yl)-1H-indole-5-carboximidamide Investigative 45270104 C14H10Cl2N4 305.2 C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=CC(=NC(=C3)Cl)Cl IC50 = 291000 nM Non binder T95947 Acid-sensing ion channel 3 BSRI85 1,3-Benzothiazol-2-ylmethylamine Investigative 350414 C8H8N2S 164.23 C1=CC=C2C(=C1)N=C(S2)CN IC50 = 363000 nM Non binder T95947 Acid-sensing ion channel 3 BST94W 2-Amino-6-phenylpyridine Investigative 598430 C11H10N2 170.21 C1=CC=C(C=C1)C2=NC(=CC=C2)N IC50 = 763000 nM Non binder