TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T02702	Bacterial Dihydrofolate reductase	B5D8ZM	3-(4,6-Diamino-2,2-dimethyl-1,3,5-triazin-1-yl)benzenesulfonamide	Investigative	10357216	C11H16N6O2S	296.35	CC1(N=C(N=C(N1C2=CC(=CC=C2)S(=O)(=O)N)N)N)C	Ki = 70794.58 nM	Poor binder
T02702	Bacterial Dihydrofolate reductase	BADE85	6-[(N-Methylanilino)methyl]pyrido[2,3-d]pyrimidine-2,4-diamine	Investigative	511808	C15H16N6	280.33	CN(CC1=CC2=C(N=C(N=C2N=C1)N)N)C3=CC=CC=C3	IC50 = 100000 nM	Poor binder
T02702	Bacterial Dihydrofolate reductase	BEU2Z9	2,4-Diamino-5-benzyl-6-methylthieno[2,3-d]pyrimidine	Investigative	457384	C14H14N4S	270.35	CC1=C(C2=C(N=C(N=C2S1)N)N)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T02702	Bacterial Dihydrofolate reductase	BL4K8O	5-[3-(2,5-Dimethoxyphenyl)propyl]thieno[2,3-d]pyrimidine-2,4-diamine	Investigative	457379	C17H20N4O2S	344.4	COC1=CC(=C(C=C1)OC)CCCC2=CSC3=NC(=NC(=C23)N)N	IC50 = 55000 nM	Poor binder
T02702	Bacterial Dihydrofolate reductase	BPKY93	5,6,7,8,9,10,11,12,13,14-Decahydro-15-thia-1,3-diaza-cyclododeca[a]indene-2,4-diamine	Investigative	456251	C16H24N4S	304.5	C1CCCCCC2=C(CCCC1)C3=C(N=C(N=C3S2)N)N	IC50 ~ 50000 nM	Poor binder
T02702	Bacterial Dihydrofolate reductase	BX83EG	5-(4-Chlorophenyl)-6-methyl-thieno[2,3-d]pyrimidine-2,4-diamine	Investigative	457383	C13H11ClN4S	290.77	CC1=C(C2=C(N=C(N=C2S1)N)N)C3=CC=C(C=C3)Cl	IC50 ~ 70000 nM	Poor binder