TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T20401	Carbonic anhydrase II	D0C8EU	Temozolomide	Approved	5394	C6H6N6O2	194.15	CN1C(=O)N2C=NC(=C2N=N1)C(=O)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	D0TG1H	Diclofenac	Approved	3033	C14H11Cl2NO2	296.1	C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0V8QT	Chlorambucil	Approved	2708	C14H19Cl2NO2	304.2	C1=CC(=CC=C1CCCC(=O)O)N(CCCl)CCCl	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	D09XQU	Tirapazamine	Phase 3	135413511	C7H6N4O2	178.15	.	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	D0H6GI	VE-822	Phase 1	59472121	C24H25N5O3S	463.6	CC(C)S(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C3=CC(=NO3)C4=CC=C(C=C4)CNC)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	D0F8XZ	PMID30074415-Compound-20	Patented	19890	C9H6OS	162.21	C1=CC=C2C(=C1)C=CC(=S)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0X2AU	Selenium compound 1	Patented	23427	C6H6O2Se	189.08	C1=CC=C(C=C1)[Se](=O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D07XPE	Phenformin	Withdrawn from market	8249	C10H15N5	205.26	C1=CC=C(C=C1)CCN=C(N)N=C(N)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	D0LD9S	SPERMINE	Terminated	1103	C10H26N4	202.34	C(CCNCCCN)CNCCCN	Ki = 84000 nM	Poor binder
T20401	Carbonic anhydrase II	B06PKN	Sulfaguanidine	Investigative	5324	C7H10N4O2S	214.25	C1=CC(=CC=C1N)S(=O)(=O)N=C(N)N	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B08IMB	Benzyl ferulate	Investigative	7766335	C17H16O4	284.31	COC1=C(C=CC(=C1)/C=C/C(=O)OCC2=CC=CC=C2)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B0CDZ5	N-[(5-Bromo-1-benzothien-3-yl)methyl]sulfamide	Investigative	11666911	C9H9BrN2O2S2	321.2	C1=CC2=C(C=C1Br)C(=CS2)CNS(=O)(=O)N	IC50 = 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B0HA9F	2H-1-Benzothiopyran-2-thione	Investigative	640625	C9H6S2	178.3	C1=CC=C2C(=C1)C=CC(=S)S2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B0M8OH	2-[2-(3-Nitrophenyl)-2-oxoethyl]-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Investigative	51059586	C15H10N2O6S	346.3	C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CC(=O)C3=CC(=CC=C3)[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B0O2ZB	2H-1-Benzopyran-2-one, 7-(alpha-D-mannopyranosyloxy)-4-methyl-	Investigative	2733782	C16H18O8	338.31	CC1=CC(=O)OC2=C1C=CC(=C2)O[C@@H]3[C@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B0P3RJ	2-(3-Hydroxyphenyl)ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate	Investigative	122193251	C18H18O5	314.3	COC1=C(C=CC(=C1)/C=C/C(=O)OCCC2=CC(=CC=C2)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B0U7NX	[(9R,11R)-11-Hydroxy-9-tricyclo[6.2.1.02,7]undeca-2,4,6-trienyl] nitrate	Investigative	46888470	C11H11NO4	221.21	C1[C@H](C2[C@@H](C1C3=CC=CC=C23)O)O[N+](=O)[O-]	IC50 = 98100 nM	Poor binder
T20401	Carbonic anhydrase II	B10JKE	[(1R,2R,5S,6S)-5-Bromo-9-oxabicyclo[4.2.1]nonan-2-yl] nitrate	Investigative	46888469	C8H12BrNO4	266.09	C1C[C@H]2[C@H](CC[C@H]([C@@H]1O2)O[N+](=O)[O-])Br	IC50 = 110000 nM	Poor binder
T20401	Carbonic anhydrase II	B14KWS	5-[2-Ethoxy-5-(4-methylpiperazinosulfonyl)phenyl]-3-methyl-1-p-tolyl-1H-pyrazolo[4,3-e][1,2,4]triazine	Investigative	122179847	C25H29N7O3S	507.6	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C3=NC4=C(N=N3)N(N=C4C)C5=CC=C(C=C5)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B19UHR	1,3-Dimethyluracil	Investigative	70122	C6H8N2O2	140.14	CN1C=CC(=O)N(C1=O)C	Ki = 166400 nM	Poor binder
T20401	Carbonic anhydrase II	B19YJC	5-Naphthalen-2-yl-1H-pyrazole-3-carboxylic acid	Investigative	776418	C14H10N2O2	238.24	C1=CC=C2C=C(C=CC2=C1)C3=NNC(=C3)C(=O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B1BXO5	2-(Hydroxymethyl)-N-[(2-nitrophenyl)methyl]benzenesulfonamide	Investigative	76325452	C14H14N2O5S	322.34	C1=CC=C(C(=C1)CNS(=O)(=O)C2=CC=CC=C2CO)[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B1GO9W	Fraxidin	Investigative	3083616	C11H10O5	222.19	COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B1I0WN	2-[2-(2-Nitrophenyl)-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one	Investigative	76310908	C15H10N2O6S	346.3	C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CC(=O)C3=CC=CC=C3[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B1JOZ8	Bis(2-nitrophenyl) diselenide	Investigative	101424	C12H8N2O4Se2	402.1	C1=CC=C(C(=C1)[N+](=O)[O-])[Se][Se]C2=CC=CC=C2[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B1O3CZ	Xanthoxyletin	Investigative	66548	C15H14O4	258.269	CC1(C=CC2=C(O1)C=C3C(=C2OC)C=CC(=O)O3)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B1T4JB	7-Hydroxy-8-methoxycoumarin	Investigative	5316302	C10H8O4	192.17	COC1=C(C=CC2=C1OC(=O)C=C2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B20WHU	[(1S,2S,4S,5S)-2,4-Dihydroxy-5-nitrooxycyclohexyl] nitrate	Investigative	46888472	C6H10N2O8	238.15	C1[C@@H]([C@H](C[C@@H]([C@H]1O)O[N+](=O)[O-])O[N+](=O)[O-])O	IC50 = 86300 nM	Poor binder
T20401	Carbonic anhydrase II	B2BE6I	6-Methylquinoline-8-thiol	Investigative	13008156	C10H9NS	175.25	CC1=CC2=C(C(=C1)S)N=CC=C2	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B2GTY0	Peroxydisulfuric acid	Investigative	24413	H2O8S2	194.15	OS(=O)(=O)OOS(=O)(=O)O	Ki = 84000 nM	Poor binder
T20401	Carbonic anhydrase II	B2GZ8X	Avicennin	Investigative	5321265	C20H20O4	324.4	CC(=C)/C=C/C1=C(C2=C(C3=C1OC(=O)C=C3)OC(C=C2)(C)C)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B2I3LF	3-Amino-4-hydroxy-N,5-dinitrobenzenesulfonamide	Investigative	127052516	C6H6N4O7S	278.2	C1=C(C=C(C(=C1N)O)[N+](=O)[O-])S(=O)(=O)N[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B2MZS7	7-Hydroxy-2H-1-benzopyran-2-thione	Investigative	135442220	C9H6O2S	178.21	C1=CC(=CC2=C1C=CC(=S)O2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B2POB8	Fraxin	Investigative	5273568	C16H18O10	370.31	COC1=C(C(=C2C(=C1)C=CC(=O)O2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B2RG5L	N-(N-Boc-sulfamoyl)glycine Methyl Ester	Investigative	44590306	C8H16N2O6S	268.29	CC(C)(C)OC(=O)NS(=O)(=O)NCC(=O)OC	Ki = 55700 nM	Poor binder
T20401	Carbonic anhydrase II	B2U4QH	Thiochromen-2-one	Investigative	10953838	C9H6OS	162.21	C1=CC=C2C(=C1)C=CC(=O)S2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B2VGP3	(E)-4-((4-(Benzyloxy)benzylidene)amino)benzenesulfonamide	Investigative	1377410	C20H18N2O3S	366.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)C=NC3=CC=C(C=C3)S(=O)(=O)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B36YTS	3-(4-Methoxyphenyl)-4-tosyl-3,4-dihydro-2H-1,4-benzoselenazine	Investigative	101564149	C22H21NO3SSe	458.4	CC1=CC=C(C=C1)S(=O)(=O)N2C(C[Se]C3=CC=CC=C32)C4=CC=C(C=C4)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B3AIB1	2-[(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-2,3-dihydro-1lambda6,2-benzothiazole-1,1,3-trione	Investigative	341082	C16H10N2O5S	342.3	C1=CC=C2C(=C1)C(=O)N(C2=O)CN3C(=O)C4=CC=CC=C4S3(=O)=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B3AUY6	(3S)-3-[(Sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	16718572	C9H12N2O4S	244.27	C1[C@@H](OC2=CC=CC=C2O1)CNS(=O)(=O)N	IC50 = 97000 nM	Poor binder
T20401	Carbonic anhydrase II	B3C1UB	5-(4-Methoxyphenyl)-1H-pyrazole-3-carboxylic acid	Investigative	1085887	C11H10N2O3	218.21	COC1=CC=C(C=C1)C2=NNC(=C2)C(=O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B3DY2A	[(3-Methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carbonyl)amino] sulfamate	Investigative	137653170	C6H7N7O5S	289.23	CN1C(=O)N2C=NC(=C2N=N1)C(=O)NOS(=O)(=O)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B3FG4V	3-(4-Hydroxyphenyl)propenoic acid 3-hydroxyphenethyl ester	Investigative	122193252	C17H16O4	284.31	C1=CC(=CC(=C1)O)CCOC(=O)/C=C/C2=CC=C(C=C2)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B3FQR9	N,N'-Dicyclohexylsulfamide	Investigative	12765315	C12H24N2O2S	260.399	C1CCC(CC1)NS(=O)(=O)NC2CCCCC2	Ki = 100100 nM	Poor binder
T20401	Carbonic anhydrase II	B3LQ6P	3-[[Methyl(sulfamoyl)amino]methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	17751568	C10H14N2O4S	258.3	CN(CC1COC2=CC=CC=C2O1)S(=O)(=O)N	IC50 = 85000 nM	Poor binder
T20401	Carbonic anhydrase II	B3PS0L	7-(Allyloxy)-2H-chromene-2-thione	Investigative	57387636	C12H10O2S	218.27	C=CCOC1=CC2=C(C=C1)C=CC(=S)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B3S4MQ	7-[[(2E)-3,7-Dimethyl-6-oxo-7-hydroxy-2-octenyl]oxy]coumarin	Investigative	5358858	C19H22O5	330.4	C/C(=C\\COC1=CC2=C(C=C1)C=CC(=O)O2)/CCC(=O)C(C)(C)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B3U5IQ	2-(2-Fluorobenzyl)-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Investigative	2471990	C14H10FNO3S	291.3	C1=CC=C(C(=C1)CN2C(=O)C3=CC=CC=C3S2(=O)=O)F	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B41EJD	N-(2-Fluorobenzylidene)(phenyl)methanamine	Investigative	44221747	C14H12FN	213.25	C1=CC=C(C=C1)CN=CC2=CC=CC=C2F	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B45FEU	2,6-Dimethylphenol	Investigative	11335	C8H10O	122.16	CC1=C(C(=CC=C1)C)O	Ki = 113500 nM	Poor binder
T20401	Carbonic anhydrase II	B4AZQ5	Benzyl-(2-fluoro-benzyl)-amine	Investigative	810867	C14H14FN	215.27	C1=CC=C(C=C1)CNCC2=CC=CC=C2F	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B4BRS6	2-[3-[2-(3-Hydroxyphenyl)ethoxy]phenyl]ethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate	Investigative	122193190	C25H24O6	420.5	C1=CC(=CC(=C1)O)CCOC2=CC=CC(=C2)CCOC(=O)/C=C/C3=CC(=C(C=C3)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B4MB8P	6-Bromo-2,2-dioxo-1,2-benzoxathiine	Investigative	20195196	C8H5BrO3S	261.089	C1=CC2=C(C=CS(=O)(=O)O2)C=C1Br	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B4NO8M	3-(4-Methoxyphenyl)-4-tosyl-6-chloro-3,4-dihydro-2H-1,4-benzoselenazine	Investigative	132547793	C22H20ClNO3SSe	492.9	CC1=CC=C(C=C1)S(=O)(=O)N2C(C[Se]C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B4NUD1	5,6-Dihydro-2H-pyran-2-one	Investigative	520660	C5H6O2	98.1	C1COC(=O)C=C1	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B4TU6Y	2,3,4,5,6-Pentafluoro-N-(5-mercapto-[1,3,4]thiadiazol-2-yl)-benzamide	Investigative	44401975	C9H2F5N3OS2	327.3	C1(=C(C(=C(C(=C1F)F)F)F)F)C(=O)NC2=NNC(=S)S2	Ki = 129000 nM	Poor binder
T20401	Carbonic anhydrase II	B51YIE	4-Morpholinosulfonylmorpholine	Investigative	219987	C8H16N2O4S	236.29	C1COCCN1S(=O)(=O)N2CCOCC2	Ki = 135000 nM	Poor binder
T20401	Carbonic anhydrase II	B53EFH	6-Acetyl-7-(2-adamantan-1-yl-ethoxy)-chromen-2-one	Investigative	52944864	C23H26O4	366.4	CC(=O)C1=C(C=C2C(=C1)C=CC(=O)O2)OCCC34CC5CC(C3)CC(C5)C4	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B54BNM	Sodium 2-ethylhexanoate	Investigative	23672331	C8H15NaO2	166.19	CCCCC(CC)C(=O)[O-].[Na+]	Ki = 93000 nM	Poor binder
T20401	Carbonic anhydrase II	B56MGL	N-Hydroxy-3-(4-chlorophenyl)-4,5-dihydroisoxazole-5-carboxamide	Investigative	76328450	C10H9ClN2O3	240.64	C1C(ON=C1C2=CC=C(C=C2)Cl)C(=O)NO	Ki = 94500 nM	Poor binder
T20401	Carbonic anhydrase II	B5E6UV	N-Hydroxybenzamide	Investigative	10313	C7H7NO2	137.14	C1=CC=C(C=C1)C(=O)NO	Ki = 179000 nM	Poor binder
T20401	Carbonic anhydrase II	B5E9YP	3-(3,4-Dimethylphenyl)-1H-pyrazole-5-carboxylic acid	Investigative	4598704	C12H12N2O2	216.24	CC1=C(C=C(C=C1)C2=NNC(=C2)C(=O)O)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B5LGO2	2-Ethylhexanoic acid	Investigative	8697	C8H16O2	144.21	CCCCC(CC)C(=O)O	Ki = 93000 nM	Poor binder
T20401	Carbonic anhydrase II	B5UC6Z	Hymecromone	Investigative	5280567	C10H8O3	176.17	CC1=CC(=O)OC2=C1C=CC(=C2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B5V1CM	(E)-4-(6-Methoxynaphthalen-2-yl)-1-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-one	Investigative	101913753	C21H24O7	388.4	COC1=CC2=C(C=C1)C=C(C=C2)/C=C/C(=O)C[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B6G5WX	3,4-Dimethoxy-N-phenylbenzenesulfonamide	Investigative	740560	C14H15NO4S	293.34	COC1=C(C=C(C=C1)S(=O)(=O)NC2=CC=CC=C2)OC	IC50 ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B6K2SQ	5-[1-Hydroxy-2-[[2-hydroxy-2-(3-hydroxy-4-methoxyphenyl)ethyl]diselanyl]ethyl]-2-methoxyphenol	Investigative	137642864	C18H22O6Se2	492.3	COC1=C(C=C(C=C1)C(C[Se][Se]CC(C2=CC(=C(C=C2)OC)O)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B6M5YW	Chembl4169120	Investigative	145953247	C26H18N2O3S	438.5	C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)N3C=C(C4=CC=CC=C43)/C=C/C(=O)C5=CC=NC=C5	IC50 = 65220 nM	Poor binder
T20401	Carbonic anhydrase II	B6MLE0	Fraxetin	Investigative	5273569	C10H8O5	208.17	COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)O	Ki = 94300 nM	Poor binder
T20401	Carbonic anhydrase II	B6N0FA	5-(4-Chlorophenyl)-1H-pyrazole-3-carboxylic acid	Investigative	738819	C10H7ClN2O2	222.63	C1=CC(=CC=C1C2=NNC(=C2)C(=O)O)Cl	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B6TPM1	6-Nitrobenzo[d]isothiazol-3(2H)-one 1,1-dioxide	Investigative	100187	C7H4N2O5S	228.18	C1=CC2=C(C=C1[N+](=O)[O-])S(=O)(=O)NC2=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B6YRW0	6-(Benzyloxy)-1,2-benzooxathiin 2,2-dioxide	Investigative	71716939	C15H12O4S	288.3	C1=CC=C(C=C1)COC2=CC3=C(C=C2)OS(=O)(=O)C=C3	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B6Z4IJ	N,N'-Bis(2-aminoethyl)-1,3-propanediamine	Investigative	78479	C7H20N4	160.26	C(CNCCN)CNCCN	Ki = 75000 nM	Poor binder
T20401	Carbonic anhydrase II	B79GNL	2-(7-Methoxy-2-oxochromen-8-yl)-3-methylbut-2-enal	Investigative	179620	C15H14O4	258.269	CC(=C(C=O)C1=C(C=CC2=C1OC(=O)C=C2)OC)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B7AD9Q	Alloxanthoxyletin	Investigative	5317485	C15H14O4	258.269	CC1(C=CC2=C(C=C3C(=C2O1)C=CC(=O)O3)OC)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B7GVW8	Isophellodenol C	Investigative	71720036	C14H14O4	246.26	C/C(=C\\CC1=C(C=C2C(=C1)C=CC(=O)O2)O)/CO	Ki = 78900 nM	Poor binder
T20401	Carbonic anhydrase II	B7JL9K	2H-1-Benzopyran-2-one, 7-(2-propynyloxy)-	Investigative	3051101	C12H8O3	200.19	C#CCOC1=CC2=C(C=C1)C=CC(=O)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B7LJ2S	7-Pent-4-ynoxychromene-2-thione	Investigative	90180909	C14H12O2S	244.31	C#CCCCOC1=CC2=C(C=C1)C=CC(=S)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B7N3DZ	Sodium thiocyanate	Investigative	516871	CNNaS	81.07	C(#N)[S-].[Na+]	Ki = 200000 nM	Poor binder
T20401	Carbonic anhydrase II	B7OC3B	delta-Valerolactone	Investigative	10953	C5H8O2	100.12	C1CCOC(=O)C1	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B7R4UX	4-Amino-3-fluorobenzenesulfonamide	Investigative	4687472	C6H7FN2O2S	190.2	C1=CC(=C(C=C1S(=O)(=O)N)F)N	Ki = 60000 nM	Poor binder
T20401	Carbonic anhydrase II	B7SB9A	3,4,4'-Tri-O-methylellagic acid	Investigative	11674590	C17H12O8	344.3	COC1=C(C2=C3C(=C1)C(=O)OC4=C3C(=CC(=C4OC)OC)C(=O)O2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B80VYC	6-Acetyl-7-(benzyloxy)-2H-chromen-2-one	Investigative	52943614	C18H14O4	294.3	CC(=O)C1=C(C=C2C(=C1)C=CC(=O)O2)OCC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B85XES	3-((Benzylimino)methyl)benzoic acid	Investigative	44221944	C15H13NO2	239.27	C1=CC=C(C=C1)CN=CC2=CC(=CC=C2)C(=O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B86CUA	1-(2-Nitrophenyl)-N-[6-[(2-nitrophenyl)methylideneamino]hexyl]methanimine	Investigative	260244	C20H22N4O4	382.4	C1=CC=C(C(=C1)C=NCCCCCCN=CC2=CC=CC=C2[N+](=O)[O-])[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B87UWE	Scopolin	Investigative	439514	C16H18O9	354.31	COC1=C(C=C2C(=C1)C=CC(=O)O2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B8BA1U	N-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)sulfuric diamide	Investigative	17751566	C9H12N2O4S	244.27	C1C(OC2=CC=CC=C2O1)CNS(=O)(=O)N	IC50 = 130000 nM	Poor binder
T20401	Carbonic anhydrase II	B8BE6W	(2S(R),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl nitrate	Investigative	46845029	C7H11NO4	173.17	C1CC2[C@H](CC1[C@H]2O)O[N+](=O)[O-]	IC50 = 73100 nM	Poor binder
T20401	Carbonic anhydrase II	B8G1ND	6-Hydroxycoumarin	Investigative	99477	C9H6O3	162.14	C1=CC2=C(C=CC(=O)O2)C=C1O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B8GM6Q	2,2-Dioxo-1,2lambda6-benzoxathiin-6-ol	Investigative	71717570	C8H6O4S	198.2	C1=CC2=C(C=CS(=O)(=O)O2)C=C1O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B8KHF6	N,4-Dimethyl-N-phenylbenzenesulfonamide	Investigative	220023	C14H15NO2S	261.339	CC1=CC=C(C=C1)S(=O)(=O)N(C)C2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B8M9RI	N,N-Dicyclohexylsulfamide	Investigative	20360268	C12H24N2O2S	260.399	C1CCC(CC1)N(C2CCCCC2)S(=O)(=O)N	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B8RU5Y	[(1S,2S,3R,4R)-2,3-Dihydroxy-4-nitrooxycyclohexyl] nitrate	Investigative	46888473	C6H10N2O8	238.15	C1C[C@@H]([C@H]([C@H]([C@@H]1O[N+](=O)[O-])O)O)O[N+](=O)[O-]	IC50 = 129000 nM	Poor binder
T20401	Carbonic anhydrase II	B8TDZ9	Spermine(hbbh)	Investigative	389642	C20H42N4O4	402.6	CC(C)(C)OC(=O)N(CCCCN(CCCN)C(=O)OC(C)(C)C)CCCN	Ki = 110000 nM	Poor binder
T20401	Carbonic anhydrase II	B8X1OC	gamma-Valerolactone	Investigative	7921	C5H8O2	100.12	CC1CCC(=O)O1	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B90WVX	6-(Allyloxy)-2H-chromene-2-thione	Investigative	57386889	C12H10O2S	218.27	C=CCOC1=CC2=C(C=C1)OC(=S)C=C2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B97PFE	1,3-Dibromo-5-[(2,3-dibromo-4,5-dimethoxyphenyl)methyl]-2,4,6-trimethoxybenzene	Investigative	23426698	C18H18Br4O5	633.9	COC1=C(C(=C(C(=C1)CC2=C(C(=C(C(=C2OC)Br)OC)Br)OC)Br)Br)OC	Ki = 60170 nM	Poor binder
T20401	Carbonic anhydrase II	B9EH3C	(2S)-6-Fluoro-2-[(sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	72737584	C9H11FN2O4S	262.26	C1[C@@H](OC2=C(O1)C=C(C=C2)F)CNS(=O)(=O)N	IC50 = 75000 nM	Poor binder
T20401	Carbonic anhydrase II	B9HVM6	3-(4-Hydroxyphenyl)-1H-pyrazole-5-carboxylic acid	Investigative	135645043	C10H8N2O3	204.18	C1=CC(=CC=C1C2=NNC(=C2)C(=O)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B9RK1L	3-[(3-Bromophenyl)methoxy]-1,2-benzothiazole 1,1-dioxide	Investigative	76314550	C14H10BrNO3S	352.2	C1=CC=C2C(=C1)C(=NS2(=O)=O)OCC3=CC(=CC=C3)Br	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	B9VF2T	2(5H)-Furanone	Investigative	10341	C4H4O2	84.07	C1C=CC(=O)O1	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B9VZK2	Chembl4164724	Investigative	145958328	C19H18N2O3S	354.4	CCCS(=O)(=O)N1C=C(C2=CC=CC=C21)/C=C/C(=O)C3=CC=NC=C3	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	B9Z6GL	Sulfamic acid	Investigative	5987	H3NO3S	97.1	NS(=O)(=O)O	Ki = 97000 nM	Poor binder
T20401	Carbonic anhydrase II	B9ZCR0	Methyl (2S)-2-[(4-methylphenyl)sulfonylamino]-3-phenylpropanoate	Investigative	728666	C17H19NO4S	333.4	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C(=O)OC	Ki = 97400 nM	Poor binder
T20401	Carbonic anhydrase II	BA1HF6	Sodium selenocyanate	Investigative	13927398	CNNaSe	127.98	C(#N)[Se-].[Na+]	Ki = 86000 nM	Poor binder
T20401	Carbonic anhydrase II	BA6WL5	7-(1-Phenyl-1H-1,2,3-triazole-4-ylmethoxy)-2H-1-benzopyran-2-one	Investigative	88314336	C18H13N3O3	319.3	C1=CC=C(C=C1)N2C=C(N=N2)COC3=CC4=C(C=C3)C=CC(=O)O4	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BAB06K	1,1'-Selanediyldi(3-benzyloxypropan-2-ol)	Investigative	122386532	C20H26O4Se	409.4	C1=CC=C(C=C1)COCC(C[Se]CC(COCC2=CC=CC=C2)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BAE07S	7-(Prop-2-ynyloxy)-2H-chromen-2-thione	Investigative	57387395	C12H8O2S	216.26	C#CCOC1=CC2=C(C=C1)C=CC(=S)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BAPX68	3-[(Sulfamoylamino)methyl]-1-benzothiophene	Investigative	11687376	C9H10N2O2S2	242.3	C1=CC=C2C(=C1)C(=CS2)CNS(=O)(=O)N	IC50 = 66000 nM	Poor binder
T20401	Carbonic anhydrase II	BAT46O	3-(4-Ethylphenyl)-1H-pyrazole-5-carboxylic acid	Investigative	3524248	C12H12N2O2	216.24	CCC1=CC=C(C=C1)C2=NNC(=C2)C(=O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BAZ3I0	4-(Aminomethyl)-N-nitrobenzenesulfonamide	Investigative	127052812	C7H9N3O4S	231.23	C1=CC(=CC=C1CN)S(=O)(=O)N[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BB25JQ	Sodium 4-Ethyloctanoate	Investigative	54581017	C10H19NaO2	194.25	CCCCC(CC)CCC(=O)[O-].[Na+]	Ki = 96000 nM	Poor binder
T20401	Carbonic anhydrase II	BB39EI	Methyl 2-(4-methylphenylsulfonamido)acetate	Investigative	562880	C10H13NO4S	243.28	CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)OC	Ki = 56400 nM	Poor binder
T20401	Carbonic anhydrase II	BB3C2K	N-(p-Toluenesulfonyl)-L-phenylalanine	Investigative	99327	C16H17NO4S	319.4	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O	Ki = 103900 nM	Poor binder
T20401	Carbonic anhydrase II	BB6OS5	6-(4-Methylsulfonylphenyl)-N-phenyl-3-(sulfamoylamino)pyrazine-2-carboxamide	Investigative	121382833	C18H17N5O5S2	447.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)NS(=O)(=O)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BBQ42W	7-Allyloxycoumarin	Investigative	327169	C12H10O3	202.21	C=CCOC1=CC2=C(C=C1)C=CC(=O)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BC1E3A	6-(3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decan-1-ylmethyl)chromen-2-one;chloride	Investigative	45485271	C16H19ClN4O2	334.8	C1N2CN3CN1C[N+](C2)(C3)CC4=CC5=C(C=C4)OC(=O)C=C5.[Cl-]	Ki = 72300 nM	Poor binder
T20401	Carbonic anhydrase II	BC4FG5	6-[Tert-butyl(dimethyl)silyl]oxychromen-2-one	Investigative	57384052	C15H20O3Si	276.4	CC(C)(C)[Si](C)(C)OC1=CC2=C(C=C1)OC(=O)C=C2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BC61MZ	(2S)-2-Amino-4-[(3-methoxy-6H-benzo[c]thiochromen-9-yl)amino]butanoic acid	Investigative	127026979	C18H20N2O3S	344.4	COC1=CC2=C(C=C1)C3=C(CS2)C=CC(=C3)NCC[C@@H](C(=O)O)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BC6P3G	2H-1-Benzopyran-2-one, 4-methyl-7-(beta-D-ribopyranosyloxy)-	Investigative	191826	C15H16O7	308.28	CC1=CC(=O)OC2=C1C=CC(=C2)O[C@H]3[C@@H]([C@@H]([C@@H](CO3)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BCHD15	6-[Tert-butyl(dimethyl)silyl]oxychromene-2-thione	Investigative	57386885	C15H20O2SSi	292.5	CC(C)(C)[Si](C)(C)OC1=CC2=C(C=C1)OC(=S)C=C2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BCL43W	Sodium isovalerate	Investigative	23673832	C5H9NaO2	124.11	CC(C)CC(=O)[O-].[Na+]	Ki = 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BCU2R4	(E)-Benzyl 3-(4-hydroxyphenyl)acrylate	Investigative	10083644	C16H14O3	254.28	C1=CC=C(C=C1)COC(=O)/C=C/C2=CC=C(C=C2)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BD1CR0	N,N-Diisopropylsulfamide	Investigative	19782950	C6H16N2O2S	180.27	CC(C)N(C(C)C)S(=O)(=O)N	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BD29QU	4-Methyl-N-phenylbenzenesulfonamide	Investigative	2456	C13H13NO2S	247.31	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BD4H3Y	(2R(S),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl nitrate	Investigative	44511333	C7H11NO4	173.17	C1CC2[C@@H](CC1[C@H]2O)O[N+](=O)[O-]	IC50 = 65100 nM	Poor binder
T20401	Carbonic anhydrase II	BD5T4V	4-Methoxy-2(5H)-furanone	Investigative	643477	C5H6O3	114.1	COC1=CC(=O)OC1	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BD5T8B	[(2R,3S,4R,5S,6S)-3,4,5-Triacetyloxy-6-[(E)-4-(3-methoxyphenyl)-2-oxobut-3-enyl]oxan-2-yl]methyl acetate	Investigative	101913752	C25H30O11	506.5	CC(=O)OC[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)CC(=O)/C=C/C2=CC(=CC=C2)OC)OC(=O)C)OC(=O)C)OC(=O)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BDGT91	2-[(3,4-Dichlorophenyl)methyl]-2,3-dihydro-1lambda6,2-benzothiazole-1,1,3-trione	Investigative	7382231	C14H9Cl2NO3S	342.2	C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CC3=CC(=C(C=C3)Cl)Cl	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BDPK93	(E)-4-(3-Methoxyphenyl)-1-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-one	Investigative	101913751	C17H22O7	338.4	COC1=CC=CC(=C1)/C=C/C(=O)C[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BDT5A9	[(2R,3S,4R,5S,6S)-3,4,5-Triacetyloxy-6-[(E)-4-(6-methoxynaphthalen-2-yl)-2-oxobut-3-enyl]oxan-2-yl]methyl acetate	Investigative	101913750	C29H32O11	556.6	CC(=O)OC[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)CC(=O)/C=C/C2=CC3=C(C=C2)C=C(C=C3)OC)OC(=O)C)OC(=O)C)OC(=O)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BDUK84	(5-Imino-2-sulfonic acid furane)(phenyl)methanamine	Investigative	44221748	C12H11NO4S	265.29	C1=CC=C(C=C1)CN=CC2=CC=C(O2)S(=O)(=O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BE9U8Z	3-(4-Isopropylphenyl)-1H-pyrazole-5-carboxylic acid	Investigative	975396	C13H14N2O2	230.26	CC(C)C1=CC=C(C=C1)C2=NNC(=C2)C(=O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BEG3I1	2H-Pyran-2-one	Investigative	68154	C5H4O2	96.08	C1=CC(=O)OC=C1	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BEK42O	Lamellarin E	Investigative	5491996	C29H25NO9	531.5	COC1=C(C=C(C=C1)C2=C3C4=CC(=C(C(=C4CCN3C5=C2C6=CC(=C(C=C6OC5=O)O)OC)O)OC)OC)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BEM98Q	3-(4-Ethoxyphenyl)-4,5-dihydro-1,2-oxazole-5-carbohydrazide	Investigative	76310328	C12H15N3O3	249.27	CCOC1=CC=C(C=C1)C2=NOC(C2)C(=O)NN	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BF3VT7	Carbamic acid, [[(phenylmethyl)amino]sulfonyl]-, 1,1-dimethylethyl ester	Investigative	17757567	C12H18N2O4S	286.35	CC(C)(C)OC(=O)NS(=O)(=O)NCC1=CC=CC=C1	Ki = 161000 nM	Poor binder
T20401	Carbonic anhydrase II	BF48BA	3-(4-Methoxyphenyl)-4-(2-nitrophenylsulfonyl)-6-chloro-3,4-dihydro-2H-1,4-benzoselenazine	Investigative	132547798	C21H17ClN2O5SSe	523.9	COC1=CC=C(C=C1)C2C[Se]C3=C(N2S(=O)(=O)C4=CC=CC=C4[N+](=O)[O-])C=C(C=C3)Cl	Ki = 59600 nM	Poor binder
T20401	Carbonic anhydrase II	BF7KI0	5-[2-Ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-3-methyl-1-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazolo[4,3-e][1,2,4]triazine	Investigative	122179845	C29H37N9O5S2	655.8	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C3=NC4=C(N=N3)N(N=C4C)C5=CC=C(C=C5)S(=O)(=O)N6CCN(CC6)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BF7V0C	4-Ethoxy-N-[(2R)-2-hydroxypropyl]-3-[3-methyl-1-(4-methylphenyl)pyrazolo[4,3-e][1,2,4]triazin-5-yl]benzenesulfonamide	Investigative	122179850	C23H26N6O4S	482.6	CCOC1=C(C=C(C=C1)S(=O)(=O)NC[C@@H](C)O)C2=NC3=C(N=N2)N(N=C3C)C4=CC=C(C=C4)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BF9U3Q	(3S)-5-Chloro-3-[(sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	72737582	C9H11ClN2O4S	278.71	C1[C@@H](OC2=C(O1)C=CC=C2Cl)CNS(=O)(=O)N	IC50 = 56000 nM	Poor binder
T20401	Carbonic anhydrase II	BFGJ42	Methyl 2,2-dioxo-1,2lambda6-benzoxathiine-6-sulfonate	Investigative	71717571	C9H8O6S2	276.3	COS(=O)(=O)C1=CC2=C(C=C1)OS(=O)(=O)C=C2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BFI5Y4	N-[(2S)-Butan-2-yl]-4-ethoxy-3-[3-methyl-1-(4-methylphenyl)pyrazolo[4,3-e][1,2,4]triazin-5-yl]benzenesulfonamide	Investigative	122179851	C24H28N6O3S	480.6	CC[C@H](C)NS(=O)(=O)C1=CC(=C(C=C1)OCC)C2=NC3=C(N=N2)N(N=C3C)C4=CC=C(C=C4)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BFMA75	[2-(7-Methoxy-2-oxochromen-8-yl)-3-methylbut-3-enyl] pyridine-3-carboxylate	Investigative	14057643	C21H19NO5	365.4	CC(=C)C(COC(=O)C1=CN=CC=C1)C2=C(C=CC3=C2OC(=O)C=C3)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BFT8I4	N-[2-(Naphthalen-1-ylamino)ethyl]acetamide	Investigative	2900806	C14H16N2O	228.29	CC(=O)NCCNC1=CC=CC2=CC=CC=C21	Ki = 121000 nM	Poor binder
T20401	Carbonic anhydrase II	BG9IX6	1-Bromo-3,5-bis[(2,3-dibromo-4,5-dimethoxyphenyl)methyl]-2,4,6-trimethoxybenzene	Investigative	66573254	C27H27Br5O7	863	COC1=C(C(=C(C(=C1)CC2=C(C(=C(C(=C2OC)Br)OC)CC3=CC(=C(C(=C3Br)Br)OC)OC)OC)Br)Br)OC	Ki = 78490 nM	Poor binder
T20401	Carbonic anhydrase II	BGP5U1	Xanthyletin	Investigative	65188	C14H12O3	228.24	CC1(C=CC2=C(O1)C=C3C(=C2)C=CC(=O)O3)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BGU86Y	4-(4-Fluorophenyl)-1-(4-methanesulfonylphenyl)-3-(trifluoromethyl)-1H-pyrazole	Investigative	9952009	C17H12F4N2O2S	384.3	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(C(=N2)C(F)(F)F)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BH29CO	Sodium Isoselenocyanate	Investigative	15815634	CNNaSe	127.98	C(=[N-])=[Se].[Na+]	Ki = 86000 nM	Poor binder
T20401	Carbonic anhydrase II	BHIG92	2-[(2-Amino-4-methylphenyl)diselanyl]-5-methylaniline	Investigative	137634525	C14H16N2Se2	370.2	CC1=CC(=C(C=C1)[Se][Se]C2=C(C=C(C=C2)C)N)N	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BHJL57	Bis[2-(tosylamino)phenyl] perselenide	Investigative	5272990	C26H24N2O4S2Se2	650.6	CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2[Se][Se]C3=CC=CC=C3NS(=O)(=O)C4=CC=C(C=C4)C	Ki = 61600 nM	Poor binder
T20401	Carbonic anhydrase II	BHKO28	3-(4-Methylphenyl)-1H-pyrazole-5-carboxylic acid	Investigative	818267	C11H10N2O2	202.21	CC1=CC=C(C=C1)C2=NNC(=C2)C(=O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BHS2U8	4,6-Dimethyl-2H-pyran-2-one	Investigative	12662	C7H8O2	124.14	CC1=CC(=O)OC(=C1)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BHT81U	2-(Naphthalen-1-ylmethyl)-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Investigative	706849	C18H13NO3S	323.4	C1=CC=C2C(=C1)C=CC=C2CN3C(=O)C4=CC=CC=C4S3(=O)=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BI19WO	2-(3-Chloro-4-hydroxyphenyl)acetamide	Investigative	15038375	C8H8ClNO2	185.61	C1=CC(=C(C=C1CC(=O)N)Cl)O	Ki = 131000 nM	Poor binder
T20401	Carbonic anhydrase II	BI28NU	Sodium 4-Methylhexanoate	Investigative	54582050	C7H13NaO2	152.17	CCC(C)CCC(=O)[O-].[Na+]	Ki = 112000 nM	Poor binder
T20401	Carbonic anhydrase II	BI68RL	Dimethylfraxetin	Investigative	3083928	C12H12O5	236.22	COC1=C(C(=C2C(=C1)C=CC(=O)O2)OC)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BI94ZP	3-(2-Ethoxyphenyl)-4,5-dihydroisoxazole-5-carbohydrazide	Investigative	76317538	C12H15N3O3	249.27	CCOC1=CC=CC=C1C2=NOC(C2)C(=O)NN	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BIH87X	Bis(3-methoxysalicylidene)ethylenediamine	Investigative	5232078	C18H20N2O4	328.4	COC1=CC=CC(=C1O)C=NCCN=CC2=C(C(=CC=C2)OC)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BIKB27	N,N'-Dipropylsulfamide	Investigative	15729847	C6H16N2O2S	180.27	CCCNS(=O)(=O)NCCC	Ki = 124000 nM	Poor binder
T20401	Carbonic anhydrase II	BIM8F3	2-[4-[2-(4-Hydroxyphenyl)ethoxy]phenyl]ethyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate	Investigative	122193189	C25H24O6	420.5	C1=CC(=CC=C1CCOC2=CC=C(C=C2)CCOC(=O)/C=C/C3=CC(=C(C=C3)O)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BIT2V3	6-[4-(4-Methoxyphenyl)triazol-1-yl]-1,1-dioxo-1,2-benzothiazol-3-one	Investigative	90654826	C16H12N4O4S	356.4	COC1=CC=C(C=C1)C2=CN(N=N2)C3=CC4=C(C=C3)C(=O)NS4(=O)=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BITU79	4-Amino-3-iodobenzenesulfonamide	Investigative	9861037	C6H7IN2O2S	298.1	C1=CC(=C(C=C1S(=O)(=O)N)I)N	Ki = 70000 nM	Poor binder
T20401	Carbonic anhydrase II	BJC64B	2-Bromo-1,3,5-trimethoxy-4-(2,3-dibromo-4,5-dimethoxybenzyl)benzene	Investigative	66572313	C18H19Br3O5	555.1	COC1=CC(=C(C(=C1CC2=CC(=C(C(=C2Br)Br)OC)OC)OC)Br)OC	Ki = 54430 nM	Poor binder
T20401	Carbonic anhydrase II	BJCY32	Geiparvarin	Investigative	5910585	C19H18O5	326.3	C/C(=C\\COC1=CC2=C(C=C1)C=CC(=O)O2)/C3=CC(=O)C(O3)(C)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BJO4Q6	7-[(1-Phenyl-1H-1,2,3-triazol-4-yl)methoxy]-2H-chromene-2-thione	Investigative	86719933	C18H13N3O2S	335.4	C1=CC=C(C=C1)N2C=C(N=N2)COC3=CC4=C(C=C3)C=CC(=S)O4	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BJQN91	1,1-Dioxo-2-phenacyl-1,2-benzothiazol-3-one	Investigative	658040	C15H11NO4S	301.3	C1=CC=C(C=C1)C(=O)CN2C(=O)C3=CC=CC=C3S2(=O)=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BJW8Q5	3-[4-(Methylaminomethyl)phenyl]-5-[6-(4-propan-2-ylsulfonylphenyl)-3-(sulfamoylamino)pyrazin-2-yl]-1,2-oxazole	Investigative	121382897	C24H26N6O5S2	542.6	CC(C)S(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C3=CC(=NO3)C4=CC=C(C=C4)CNC)NS(=O)(=O)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BJXK84	1-Oxo-1-(2-sulfamoylhydrazino)-2-O,3-O:4-O,5-O-diisopropylidene-1-deoxy-beta-D-fructopyranose	Investigative	44380677	C12H21N3O8S	367.38	CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)C(=O)NNS(=O)(=O)N)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BK09PL	4-Methylumbelliferyl-galactopyranoside	Investigative	93577	C16H18O8	338.31	CC1=CC(=O)OC2=C1C=CC(=C2)O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)O	Ki = 77000 nM	Poor binder
T20401	Carbonic anhydrase II	BK3CE1	Nitridoselenidocarbon(.)	Investigative	6365232	CNSe	104.99	C(#N)[Se]	Ki = 86000 nM	Poor binder
T20401	Carbonic anhydrase II	BK7FT0	4-Allyloxycoumarin	Investigative	5133468	C12H10O3	202.21	C=CCOC1=CC(=O)OC2=CC=CC=C21	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BK95EU	(Phenylsulfonylaminomethylene)bis(phosphonic acid)	Investigative	10068042	C7H11NO8P2S	331.18	C1=CC=C(C=C1)S(=O)(=O)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BK97LM	6,8-Dichloro-1,2-benzooxathiin 2,2-dioxide	Investigative	71522163	C8H4Cl2O3S	251.09	C1=CS(=O)(=O)OC2=C1C=C(C=C2Cl)Cl	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BKJR95	6-Methoxy-1-(phenylsulfonyl)-1H-indole-2-sulfonamide	Investigative	14476488	C15H14N2O5S2	366.4	COC1=CC2=C(C=C1)C=C(N2S(=O)(=O)C3=CC=CC=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BKSM07	Avicennol	Investigative	15118768	C20H22O5	342.4	CC1(C=CC2=C(O1)C3=C(C(=C2OC)/C=C/C(C)(C)O)OC(=O)C=C3)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BKYZ35	3-((Benzylamino)methyl)benzoic acid	Investigative	45266999	C15H15NO2	241.28	C1=CC=C(C=C1)CNCC2=CC(=CC=C2)C(=O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BL02BG	4-Amino-N-nitrobenzenesulfonamide	Investigative	56689569	C6H7N3O4S	217.21	C1=CC(=CC=C1N)S(=O)(=O)N[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BL8K0P	4,6-Dimethylpyran-2-thione	Investigative	5164092	C7H8OS	140.2	CC1=CC(=S)OC(=C1)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BLB2R3	6-Aminosaccharin	Investigative	64789	C7H6N2O3S	198.2	C1=CC2=C(C=C1N)S(=O)(=O)NC2=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BLI69P	4-Methylumbelliferyl glucoside	Investigative	2733779	C16H18O8	338.31	CC1=CC(=O)OC2=C1C=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BLVK03	(2S)-5-Fluoro-2-[(sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	72737583	C9H11FN2O4S	262.26	C1[C@@H](OC2=C(O1)C(=CC=C2)F)CNS(=O)(=O)N	IC50 = 70000 nM	Poor binder
T20401	Carbonic anhydrase II	BM24TE	7-{[Tert-Butyl(dimethyl)silyl]oxy}-2H-1-benzopyran-2-one	Investigative	57386884	C15H20O3Si	276.4	CC(C)(C)[Si](C)(C)OC1=CC2=C(C=C1)C=CC(=O)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BM47FW	2-Amino-N-nitrobenzenesulfonamide	Investigative	127049999	C6H7N3O4S	217.21	C1=CC=C(C(=C1)N)S(=O)(=O)N[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BM85RG	1-[3-Chloro-4-(4-methylpiperazin-1-yl)sulfonylphenyl]-5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-3-methylpyrazolo[4,3-e][1,2,4]triazine	Investigative	122179853	C29H36ClN9O5S2	690.2	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C3=NC4=C(N=N3)N(N=C4C)C5=CC(=C(C=C5)S(=O)(=O)N6CCN(CC6)C)Cl	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BMB3K9	2-[[3-(4-Nitrophenyl)-1,2-oxazol-5-yl]methyl]-1,1-dioxo-1,2-benzothiazol-3-one	Investigative	76321814	C17H11N3O6S	385.4	C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CC3=CC(=NO3)C4=CC=C(C=C4)[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BMX78T	Sodium 2-Methylvalerate	Investigative	23673162	C6H11NaO2	138.14	CCCC(C)C(=O)[O-].[Na+]	Ki = 113000 nM	Poor binder
T20401	Carbonic anhydrase II	BN1QD0	4-Methylumbelliferyl beta-D-xylopyranoside	Investigative	92229	C15H16O7	308.28	CC1=CC(=O)OC2=C1C=CC(=C2)O[C@H]3[C@@H]([C@H]([C@@H](CO3)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BN3B0O	Sodium 2-Methylhexanoate	Investigative	23703293	C7H13NaO2	152.17	CCCCC(C)C(=O)[O-].[Na+]	Ki = 103000 nM	Poor binder
T20401	Carbonic anhydrase II	BN3LH5	(3R)-3-[(Sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine	Investigative	72737580	C9H12N2O4S	244.27	C1[C@H](OC2=CC=CC=C2O1)CNS(=O)(=O)N	IC50 = 77000 nM	Poor binder
T20401	Carbonic anhydrase II	BN4B6F	4-(Dimethylamino)-N-nitrobenzenesulfonamide	Investigative	127052811	C8H11N3O4S	245.26	CN(C)C1=CC=C(C=C1)S(=O)(=O)N[N+](=O)[O-]	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BN6JS0	6-(Allyloxy)coumarin	Investigative	12226066	C12H10O3	202.21	C=CCOC1=CC2=C(C=C1)OC(=O)C=C2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BNK20S	(3,4-Diacetyloxy-2,5,6-tribromophenyl)methyl acetate	Investigative	57397836	C13H11Br3O6	502.93	CC(=O)OCC1=C(C(=C(C(=C1Br)Br)OC(=O)C)OC(=O)C)Br	Ki = 58910 nM	Poor binder
T20401	Carbonic anhydrase II	BNKI43	2,3,6-Tribromo-4,5-dimethoxybenzyl alcohol	Investigative	57397664	C9H9Br3O3	404.88	COC1=C(C(=C(C(=C1Br)CO)Br)Br)OC	Ki = 94350 nM	Poor binder
T20401	Carbonic anhydrase II	BNQ74S	Triethylenetetramine	Investigative	5565	C6H18N4	146.23	C(CNCCNCCN)N	Ki = 64000 nM	Poor binder
T20401	Carbonic anhydrase II	BNTW42	1,1-Dioxo-6-[4-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]triazol-1-yl]-1,2-benzothiazol-3-one	Investigative	90654830	C16H18N4O9S	442.4	C1=CC2=C(C=C1N3C=C(N=N3)CO[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)S(=O)(=O)NC2=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BO2G7W	(1,1-Dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetic acid	Investigative	818753	C9H7NO5S	241.22	C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CC(=O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BOA07G	4-Ethoxy-N-(2-hydroxyethyl)-3-[3-methyl-1-(4-methylphenyl)pyrazolo[4,3-e][1,2,4]triazin-5-yl]benzenesulfonamide	Investigative	122179848	C22H24N6O4S	468.5	CCOC1=C(C=C(C=C1)S(=O)(=O)NCCO)C2=NC3=C(N=N2)N(N=C3C)C4=CC=C(C=C4)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BOXV54	4-Prop-2-enoxychromene-2-thione	Investigative	57386888	C12H10O2S	218.27	C=CCOC1=CC(=S)OC2=CC=CC=C21	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BP0KC6	Dihydrogeiparvarim	Investigative	289493	C19H20O5	328.4	CC(CCOC1=CC2=C(C=C1)C=CC(=O)O2)C3=CC(=O)C(O3)(C)C	Ki = 63400 nM	Poor binder
T20401	Carbonic anhydrase II	BP1N4K	6-[4-(4-Methoxy-2-methylphenyl)triazol-1-yl]-1,1-dioxo-1,2-benzothiazol-3-one	Investigative	90654828	C17H14N4O4S	370.4	CC1=C(C=CC(=C1)OC)C2=CN(N=N2)C3=CC4=C(C=C3)C(=O)NS4(=O)=O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BP6IF8	Naphtho[1,2-E][1,2]Oxathiine 3,3-Dioxide	Investigative	71719377	C12H8O3S	232.26	C1=CC=C2C(=C1)C=CC3=C2C=CS(=O)(=O)O3	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BP75XH	4-Amino-2-chlorophenol	Investigative	77578	C6H6ClNO	143.57	C1=CC(=C(C=C1N)Cl)O	Ki = 57500 nM	Poor binder
T20401	Carbonic anhydrase II	BP8G7H	N,N'-Dibutylsulphamide	Investigative	69809	C8H20N2O2S	208.32	CCCCNS(=O)(=O)NCCCC	Ki = 66300 nM	Poor binder
T20401	Carbonic anhydrase II	BP8KU1	Bis[2-hydroxy-3-(benzyloxy)propyl] perselenide	Investigative	102480165	C20H26O4Se2	488.4	C1=CC=C(C=C1)COCC(C[Se][Se]CC(COCC2=CC=CC=C2)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BPO16U	3-(2,4-Dimethylphenyl)-1H-pyrazole-5-carboxylic acid	Investigative	4274816	C12H12N2O2	216.24	CC1=CC(=C(C=C1)C2=NNC(=C2)C(=O)O)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BQ1I0C	2,4,6-Trifluorophenol	Investigative	519974	C6H3F3O	148.08	C1=C(C=C(C(=C1F)O)F)F	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BQ68JA	1-Hydroxy-3-(Trifluoromethyl)pyridine-2(1h)-Thione	Investigative	91362447	C6H4F3NOS	195.16	C1=CN(C(=S)C(=C1)C(F)(F)F)O	Ki = 64000 nM	Poor binder
T20401	Carbonic anhydrase II	BQ6J1F	1-(4-Chlorophenyl)-5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-3-methylpyrazolo[4,3-e][1,2,4]triazine	Investigative	122179854	C24H26ClN7O3S	528	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCN(CC2)C)C3=NC4=C(N=N3)N(N=C4C)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BQNM97	(1,1-Dioxido-3-oxo-1,2-benzothiazol-2(3h)-yl)acetonitrile	Investigative	239728	C9H6N2O3S	222.22	C1=CC=C2C(=C1)C(=O)N(S2(=O)=O)CC#N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BQXH46	Lamellarin B	Investigative	10076040	C30H25NO9	543.5	COC1=C(C=CC(=C1)C2=C3C4=CC(=C(C(=C4C=CN3C5=C2C6=CC(=C(C=C6OC5=O)O)OC)OC)OC)OC)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BR2H5X	3-(4-Hydroxyphenyl)acrylic acid 4-hydroxyphenethyl ester	Investigative	16119626	C17H16O4	284.31	C1=CC(=CC=C1CCOC(=O)/C=C/C2=CC=C(C=C2)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BR62SV	Sodium 2-Methylheptanoate	Investigative	23692005	C8H15NaO2	166.19	CCCCCC(C)C(=O)[O-].[Na+]	Ki = 110000 nM	Poor binder
T20401	Carbonic anhydrase II	BRM1Q4	(Benzo[1,3]dioxol-2-ylmethyl)sulfamide	Investigative	11379214	C8H10N2O4S	230.24	C1=CC=C2C(=C1)OC(O2)CNS(=O)(=O)N	IC50 = 71000 nM	Poor binder
T20401	Carbonic anhydrase II	BS58HU	N1,N3-Bis(2-(2,2,2-trifluoroacetamido)ethyl)-propane-1,3-diaminium trifluoroacetate	Investigative	46899573	C11H18F6N4O2	352.28	C(CNCCNC(=O)C(F)(F)F)CNCCNC(=O)C(F)(F)F	Ki = 112000 nM	Poor binder
T20401	Carbonic anhydrase II	BS70YN	[(1S,2S,4S,5S)-2,5-Dihydroxy-4-nitrooxycyclohexyl] nitrate	Investigative	46888471	C6H10N2O8	238.15	C1[C@@H]([C@H](C[C@@H]([C@H]1O[N+](=O)[O-])O)O[N+](=O)[O-])O	IC50 = 113000 nM	Poor binder
T20401	Carbonic anhydrase II	BS9T2Z	4-Ethoxy-N-[(2S)-2-hydroxypropyl]-3-[3-methyl-1-(4-methylphenyl)pyrazolo[4,3-e][1,2,4]triazin-5-yl]benzenesulfonamide	Investigative	122179849	C23H26N6O4S	482.6	CCOC1=C(C=C(C=C1)S(=O)(=O)NC[C@H](C)O)C2=NC3=C(N=N2)N(N=C3C)C4=CC=C(C=C4)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BSVL83	4-Methylumbelliferyl alpha-L-rhamnopyranoside	Investigative	26470767	C16H18O7	322.31	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC3=C(C=C2)C(=CC(=O)O3)C)O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BTA2U0	1-Oxo-1-(sulfamoylamino)-2-O,3-O:4-O,5-O-diisopropylidene-1-deoxy-beta-D-fructopyranose	Investigative	44380403	C12H20N2O8S	352.36	CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)C(=O)NS(=O)(=O)N)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BTFJ40	9-(4-Methylphenyl)sulfonyl-2,3,3a,9a-tetrahydrofuro[3,2-b][1,4]benzoselenazine	Investigative	137661006	C17H17NO3SSe	394.4	CC1=CC=C(C=C1)S(=O)(=O)N2C3C(CCO3)[Se]C4=CC=CC=C42	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BTH76O	5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid	Investigative	940540	C10H7FN2O2	206.17	C1=CC(=CC=C1C2=NNC(=C2)C(=O)O)F	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BTI7S8	N-[(2R)-Butan-2-yl]-4-ethoxy-3-[3-methyl-1-(4-methylphenyl)pyrazolo[4,3-e][1,2,4]triazin-5-yl]benzenesulfonamide	Investigative	122179852	C24H28N6O3S	480.6	CC[C@@H](C)NS(=O)(=O)C1=CC(=C(C=C1)OCC)C2=NC3=C(N=N2)N(N=C3C)C4=CC=C(C=C4)C	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BTQ12P	1,2,4-Benzenetriol	Investigative	10787	C6H6O3	126.11	C1=CC(=C(C=C1O)O)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BU4IE1	Sodium 2-Buyloctanoate	Investigative	23690537	C12H23NaO2	222.3	CCCCCCC(CCCC)C(=O)[O-].[Na+]	Ki = 83000 nM	Poor binder
T20401	Carbonic anhydrase II	BU89JC	6-Nitro-1,2-benzooxathiin 2,2-dioxide	Investigative	71522162	C8H5NO5S	227.2	C1=CC2=C(C=CS(=O)(=O)O2)C=C1[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BU8C3X	Rac-N-[1-(1-benzothien-3-yl)ethyl]sulfamide	Investigative	11637451	C10H12N2O2S2	256.3	CC(C1=CSC2=CC=CC=C21)NS(=O)(=O)N	IC50 = 130000 nM	Poor binder
T20401	Carbonic anhydrase II	BUC18J	4-Acetyl-N-phenylbenzenesulfonamide	Investigative	7022526	C14H13NO3S	275.32	CC(=O)C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BUFH20	2H-Pyran-2-thione	Investigative	638001	C5H4OS	112.15	C1=CC(=S)OC=C1	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BUZ9G2	1,2,5-Tribromo-3,4-dimethoxybenzene	Investigative	57399336	C8H7Br3O2	374.85	COC1=C(C(=C(C=C1Br)Br)Br)OC	Ki = 69120 nM	Poor binder
T20401	Carbonic anhydrase II	BV0I2K	N1,N12-Bis(trifluoroacetyl)-N4,N8-bis(t-butoxycarbonyl)spermine	Investigative	389641	C24H40F6N4O6	594.6	CC(C)(C)OC(=O)N(CCCCN(CCCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C)CCCNC(=O)C(F)(F)F	Ki = 107000 nM	Poor binder
T20401	Carbonic anhydrase II	BV6S0C	4-Hydroxycoumarin	Investigative	54682930	C9H6O3	162.14	C1=CC=C2C(=C1)C(=CC(=O)O2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BW1PD4	[[(4-Methylphenyl)sulfonylamino]-phosphonomethyl]phosphonic acid	Investigative	14151815	C8H13NO8P2S	345.21	CC1=CC=C(C=C1)S(=O)(=O)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BW7D6Q	N-p-Tosylglycine	Investigative	70653	C9H11NO4S	229.26	CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)O	Ki = 143800 nM	Poor binder
T20401	Carbonic anhydrase II	BWB7E8	7-[Tert-butyl(dimethyl)silyl]oxychromene-2-thione	Investigative	57386886	C15H20O2SSi	292.5	CC(C)(C)[Si](C)(C)OC1=CC2=C(C=C1)C=CC(=S)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BWF94O	(S)-2-(Tosylamino)-3-phenylpropionic acid benzyl ester	Investigative	11144024	C23H23NO4S	409.5	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C(=O)OCC3=CC=CC=C3	Ki = 56000 nM	Poor binder
T20401	Carbonic anhydrase II	BWU6L3	Potassium;(E)-5-hydroxypent-2-enoate	Investigative	21017876	C5H7KO3	154.21	C(CO)/C=C/C(=O)[O-].[K+]	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BX20OY	1-(4-Chlorophenyl)-5-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-3-methylpyrazolo[4,3-e][1,2,4]triazine	Investigative	122179855	C23H24ClN7O3S	514	CCOC1=C(C=C(C=C1)S(=O)(=O)N2CCNCC2)C3=NC4=C(N=N3)N(N=C4C)C5=CC=C(C=C5)Cl	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BX26GN	6-Acetyl-7-butoxy-2H-chromen-2-one	Investigative	52948047	C15H16O4	260.279	CCCCOC1=C(C=C2C=CC(=O)OC2=C1)C(=O)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BX50CN	8-Acetyl-7-(2-adamantan-1-yl-ethoxy)-chromen-2-one	Investigative	52942476	C23H26O4	366.4	CC(=O)C1=C(C=CC2=C1OC(=O)C=C2)OCCC34CC5CC(C3)CC(C5)C4	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BX70CN	(E)-4-(3-Methoxyphenyl)-1-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-one	Investigative	101913755	C17H22O7	338.4	COC1=CC=CC(=C1)/C=C/C(=O)C[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BXK3N0	1-(Phenylseleno)-3-(benzyloxy)-2-propanol	Investigative	11034581	C16H18O2Se	321.3	C1=CC=C(C=C1)COCC(C[Se]C2=CC=CC=C2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BXQ4P6	N-Benzyl-p-toluenesulfonamide	Investigative	95801	C14H15NO2S	261.339	CC1=CC=C(C=C1)S(=O)(=O)NCC2=CC=CC=C2	IC50 ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BY25AH	Thiobenzoic acid	Investigative	7414	C7H6OS	138.19	C1=CC=C(C=C1)C(=O)S	Ki = 51000 nM	Poor binder
T20401	Carbonic anhydrase II	BY2LR6	Sulfamic acid chroman-2-ylmethyl amine	Investigative	11230247	C10H14N2O3S	242.3	C1CC2=CC=CC=C2OC1CNS(=O)(=O)N	IC50 = 71000 nM	Poor binder
T20401	Carbonic anhydrase II	BY8EI3	Calanolide B	Investigative	65008	C22H26O5	370.4	CCCC1=CC(=O)OC2=C1C3=C(C=CC(O3)(C)C)C4=C2[C@@H]([C@@H]([C@H](O4)C)C)O	Ki = 50700 nM	Poor binder
T20401	Carbonic anhydrase II	BYC75Q	4-[(3,4-Dimethoxyphenyl)methyl]-1,2-dimethoxybenzene	Investigative	284045	C17H20O4	288.34	COC1=C(C=C(C=C1)CC2=CC(=C(C=C2)OC)OC)OC	Ki = 59107 nM	Poor binder
T20401	Carbonic anhydrase II	BYG5E7	1-(Phenylseleno)-2-propanol	Investigative	11183499	C9H12OSe	215.16	CC(C[Se]C1=CC=CC=C1)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BYL4J9	3-(4-Methoxyphenyl)-4-(2-nitrophenyl)sulfonyl-2,3-dihydro-1,4-benzoselenazine	Investigative	137650698	C21H18N2O5SSe	489.4	COC1=CC=C(C=C1)C2C[Se]C3=CC=CC=C3N2S(=O)(=O)C4=CC=CC=C4[N+](=O)[O-]	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BYLN73	7-Pent-4-ynoxychromen-2-one	Investigative	57387397	C14H12O3	228.24	C#CCCCOC1=CC2=C(C=C1)C=CC(=O)O2	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BZ2JG7	Sodium;[8-hydroxy-12-(3-hydroxy-4-methoxyphenyl)-7,16-dimethoxy-3-oxo-4-oxa-1-azapentacyclo[11.8.0.02,11.05,10.014,19]henicosa-2(11),5,7,9,12,14,16,18-octaen-17-yl] sulfate	Investigative	71717003	C28H22NNaO11S	603.5	COC1=C(C=C(C=C1)C2=C3C4=CC(=C(C=C4CCN3C5=C2C6=CC(=C(C=C6OC5=O)OC)O)OS(=O)(=O)[O-])OC)O.[Na+]	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BZ2PH6	1,1-Dioxo-6-[4-[2-(trifluoromethyl)phenyl]triazol-1-yl]-1,2-benzothiazol-3-one	Investigative	90654825	C16H9F3N4O3S	394.3	C1=CC=C(C(=C1)C2=CN(N=N2)C3=CC4=C(C=C3)C(=O)NS4(=O)=O)C(F)(F)F	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BZ48FD	(E)-4-(6-Methoxynaphthalen-2-yl)-1-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]but-3-en-2-one	Investigative	101913754	C21H24O7	388.4	COC1=CC2=C(C=C1)C=C(C=C2)/C=C/C(=O)C[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	BZ4MK5	Bis[(S)-2-(tosylamino)-3-phenylpropyl] perselenide	Investigative	102151151	C32H36N2O4S2Se2	734.7	CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C[Se][Se]C[C@H](CC3=CC=CC=C3)NS(=O)(=O)C4=CC=C(C=C4)C	Ki = 96100 nM	Poor binder
T20401	Carbonic anhydrase II	BZBI10	N,N-Diisobutylsulfamide	Investigative	44381123	C8H20N2O2S	208.32	CC(C)CN(CC(C)C)S(=O)(=O)N	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	BZYH06	1-[Propyl(Sulfamoyl)Amino]Propane	Investigative	20184392	C6H16N2O2S	180.27	CCCN(CCC)S(=O)(=O)N	Ki = 60300 nM	Poor binder
T20401	Carbonic anhydrase II	D00RNZ	7-(benzyloxy)-2H-chromen-2-one	Investigative	910172	C16H12O3	252.26	C1=CC=C(C=C1)COC2=CC3=C(C=C2)C=CC(=O)O3	Ki = 50300 nM	Poor binder
T20401	Carbonic anhydrase II	D00TRF	2-(benzyloxyamino)-N-hydroxyacetamide	Investigative	44423683	C9H12N2O3	196.2	C1=CC=C(C=C1)CONCC(=O)NO	Ki = 94000 nM	Poor binder
T20401	Carbonic anhydrase II	D01CXM	6-Acetyl-7-ethoxy-2H-chromen-2-one	Investigative	52949265	C13H12O4	232.23	CCOC1=C(C=C2C=CC(=O)OC2=C1)C(=O)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D01FOK	7-ethoxy-8-propionyl-2H-chromen-2-one	Investigative	52949288	C14H14O4	246.26	CCC(=O)C1=C(C=CC2=C1OC(=O)C=C2)OCC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D02JEZ	7-hydroxycoumarin	Investigative	5281426	C9H6O3	162.14	C1=CC(=CC2=C1C=CC(=O)O2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D02MAK	6-Acetyl-7-hydroxy-2H-chromen-2-one	Investigative	5705744	C11H8O4	204.18	CC(=O)C1=C(C=C2C(=C1)C=CC(=O)O2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D03LHJ	8-acetyl-7-propoxy-2H-chromen-2-one	Investigative	52946829	C14H14O4	246.26	CCCOC1=C(C2=C(C=C1)C=CC(=O)O2)C(=O)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D03NBX	P-hydroxyphenethyl trans-ferulate	Investigative	637308	C18H18O5	314.3	COC1=C(C=CC(=C1)/C=C/C(=O)OCCC2=CC=C(C=C2)O)O	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	D05QOR	SCOPOLETIN	Investigative	5280460	C10H8O4	192.17	COC1=C(C=C2C(=C1)C=CC(=O)O2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D05VSK	ETHOXYCOUMARIN	Investigative	35703	C11H10O3	190.19	CCOC1=CC2=C(C=C1)C=CC(=O)O2	Ki = 161000 nM	Poor binder
T20401	Carbonic anhydrase II	D05VUA	6-acetyl-7-methoxy-2H-chromen-2-one	Investigative	850202	C12H10O4	218.2	CC(=O)C1=C(C=C2C(=C1)C=CC(=O)O2)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D06DYP	8-methoxy-2-oxo-2H-chromene-3-carboxylic acid	Investigative	234562	C11H8O5	220.18	COC1=CC=CC2=C1OC(=O)C(=C2)C(=O)O	Ki = 62200 nM	Poor binder
T20401	Carbonic anhydrase II	D06WZG	8-acetyl-7-ethoxy-2H-chromen-2-one	Investigative	50925425	C13H12O4	232.23	CCOC1=C(C2=C(C=C1)C=CC(=O)O2)C(=O)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D07UCQ	Sodium phenylaminomethanesulfonate	Investigative	23680200	C7H8NNaO3S	209.2	C1=CC=C(C=C1)NCS(=O)(=O)[O-].[Na+]	Ki = 58300 nM	Poor binder
T20401	Carbonic anhydrase II	D08JNO	8-acetyl-7-butoxy-2H-chromen-2-one	Investigative	52943193	C15H16O4	260.279	CCCCOC1=C(C2=C(C=C1)C=CC(=O)O2)C(=O)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D09WVV	N1-(2-aminoethyl)ethane-1,2-diamine	Investigative	8111	C4H13N3	103.17	C(CNCCN)N	Ki = 118000 nM	Poor binder
T20401	Carbonic anhydrase II	D0E0RW	ISOSCOPOLETIN	Investigative	69894	C10H8O4	192.17	COC1=C(C=C2C=CC(=O)OC2=C1)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0EH0S	7-hydroxy-8-propionyl-2H-chromen-2-one	Investigative	52943164	C12H10O4	218.2	CCC(=O)C1=C(C=CC2=C1OC(=O)C=C2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0EY2F	7-hydroxy-6-propionyl-2H-chromen-2-one	Investigative	52949920	C12H10O4	218.2	CCC(=O)C1=C(C=C2C(=C1)C=CC(=O)O2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0F7KC	8-acetyl-7-methoxy-2H-chromen-2-one	Investigative	14116752	C12H10O4	218.2	CC(=O)C1=C(C=CC2=C1OC(=O)C=C2)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0G0BJ	VE-821	Investigative	51000408	C18H16N4O3S	368.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N	Ki ~ 50000 nM	Poor binder
T20401	Carbonic anhydrase II	D0J7KJ	6-acetyl-7-propoxy-2H-chromen-2-one	Investigative	52940758	C14H14O4	246.26	CCCOC1=C(C=C2C=CC(=O)OC2=C1)C(=O)C	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0K1FG	8-Acetyl-7-hydroxy-2H-chromen-2-one	Investigative	5411574	C11H8O4	204.18	CC(=O)C1=C(C=CC2=C1OC(=O)C=C2)O	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0L1AV	Trans-(1S(R),2S(R))-2-Hydroxycyclooctyl nitrate	Investigative	45273021	C8H15NO4	189.21	C1CCC[C@@H]([C@H](CC1)O)O[N+](=O)[O-]	IC50 = 181000 nM	Poor binder
T20401	Carbonic anhydrase II	D0M5MI	SC-560	Investigative	4306515	C17H12ClF3N2O	352.7	COC1=CC=C(C=C1)N2C(=CC(=N2)C(F)(F)F)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0M9IQ	Sodium N-methylphenylaminomethanesulfonate	Investigative	23665438	C8H10NNaO3S	223.23	CN(CS(=O)(=O)[O-])C1=CC=CC=C1.[Na+]	Ki = 63600 nM	Poor binder
T20401	Carbonic anhydrase II	D0O6ZD	8-acetyl-7-(benzyloxy)-2H-chromen-2-one	Investigative	14101447	C18H14O4	294.3	CC(=O)C1=C(C=CC2=C1OC(=O)C=C2)OCC3=CC=CC=C3	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0T9BB	7-methoxy-8-propionyl-2H-chromen-2-one	Investigative	52950111	C13H12O4	232.23	CCC(=O)C1=C(C=CC2=C1OC(=O)C=C2)OC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0V0FY	8-Propionyl-7-propoxy-2H-chromen-2-one	Investigative	52946831	C15H16O4	260.279	CCCOC1=C(C2=C(C=C1)C=CC(=O)O2)C(=O)CC	Ki ~ 100000 nM	Poor binder
T20401	Carbonic anhydrase II	D0X5HL	N1-(naphthalen-1-yl)ethane-1,2-diamine	Investigative	15107	C12H14N2	186.25	C1=CC=C2C(=C1)C=CC=C2NCCN	Ki = 103000 nM	Poor binder