TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T35842	Melanocortin receptor 1	B2TNJ4	N-[(2R)-3-(4-Chlorophenyl)-1-(4-cyclohexyl-4-oxidopiperazin-4-ium-1-yl)-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide	Investigative	44393430	C29H37ClN4O3	525.1	C1CCC(CC1)[N+]2(CCN(CC2)C(=O)[C@@H](CC3=CC=C(C=C3)Cl)NC(=O)C4CC5=CC=CC=C5CN4)[O-]	Ki = 152000 nM	Poor binder
T35842	Melanocortin receptor 1	B3GU7S	(R)-2-[(1H-Indol-3-ylmethyl)-amino]-3-naphthalen-2-yl-propionamide	Investigative	44265719	C22H21N3O	343.4	C1=CC=C2C=C(C=CC2=C1)C[C@H](C(=O)N)NCC3=CNC4=CC=CC=C43	Ki = 74000 nM	Poor binder
T35842	Melanocortin receptor 1	BA9C5Y	(1R,4S,6R)-N-[(2R)-1-[4-(Tert-butylcarbamoyl)-4-cyclohexylpiperidin-1-yl]-3-(4-fluorophenyl)-1-oxopropan-2-yl]-7-methyl-7-azabicyclo[2.2.2]octane-6-carboxamide	Investigative	6918851	C34H51FN4O3	582.8	CC(C)(C)NC(=O)C1(CCN(CC1)C(=O)[C@@H](CC2=CC=C(C=C2)F)NC(=O)[C@@H]3C[C@@H]4CC[C@H]3N(C4)C)C5CCCCC5	EC50 = 160000 nM	Poor binder
T35842	Melanocortin receptor 1	BIUL40	(2R)-2-Amino-N-[(2S)-5-(diaminomethylideneamino)-1-piperidin-1-ylpentan-2-yl]-3-(4-fluorophenyl)propanamide	Investigative	44453826	C20H33FN6O	392.5	C1CCN(CC1)C[C@H](CCCN=C(N)N)NC(=O)[C@@H](CC2=CC=C(C=C2)F)N	EC50 ~ 50000 nM	Poor binder
T35842	Melanocortin receptor 1	BL69PQ	(2R)-2-Amino-N-[(2S)-5-(diaminomethylideneamino)-1-oxo-1-piperidin-1-ylpentan-2-yl]-3-(4-fluorophenyl)propanamide	Investigative	44453850	C20H31FN6O2	406.5	C1CCN(CC1)C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](CC2=CC=C(C=C2)F)N	EC50 ~ 50000 nM	Poor binder