TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T39519	Lysine N-methyltransferase 1A	B01LJI	(2S)-2-Amino-5-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methyl-(2-iodoethyl)amino]pentanoic acid	Investigative	56642706	C18H28IN7O5	549.4	CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CN(CCC[C@@H](C(=O)O)N)CCI)O)O	IC50 ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	B3RL9Z	(2s)-2-Azanyl-4-[[(2s,3s,4r,5r)-5-[6-(Methylamino)purin-9-Yl]-3,4-Bis(Oxidanyl)oxolan-2-Yl]methylsulfanyl]butanoic Acid	Investigative	53377508	C15H22N6O5S	398.4	CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CSCC[C@@H](C(=O)O)N)O)O	Ki ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	B8IH2L	1-[3-[[(1S,2R,3S,4R)-4-(6-Aminopurin-9-yl)-2,3-dihydroxycyclopentyl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	76331683	C28H42N8O3	538.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2C[C@H]([C@@H]([C@@H]2O)O)N3C=NC4=C(N=CN=C43)N	Ki ~ 50000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	B8VQ0F	(2S)-2-Amino-5-[[(2R,3S,4R,5R)-5-[6-(benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl-(2-iodoethyl)amino]pentanoic acid	Investigative	56642708	C24H32IN7O5	625.5	C1=CC=C(C=C1)CNC2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CN(CCC[C@@H](C(=O)O)N)CCI)O)O	IC50 ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BD3X9I	N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-indazole-4-carboxamide	Investigative	67466175	C29H35N7O2	513.6	CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C)C	IC50 ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BF1NH9	1-(4-Tert-butylphenyl)-3-[3-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(prop-2-enylamino)purin-9-yl]oxolan-2-yl]methyl-propan-2-ylamino]propyl]urea	Investigative	70676141	C30H44N8O4	580.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)NCC=C)O)O	Ki ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BH63QB	1-[3-[[(2R,3S,4R,5R)-5-[6-(Benzylamino)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	70676142	C34H46N8O4	630.8	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)NCC5=CC=CC=C5)O)O	Ki ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BJM1F7	1-[3-[[(1R,2R,3S,4R)-4-(6-Aminopurin-9-yl)-2,3-dihydroxycyclopentyl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	76328022	C28H42N8O3	538.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@H]2C[C@H]([C@@H]([C@@H]2O)O)N3C=NC4=C(N=CN=C43)N	Ki ~ 50000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BK60CR	1-(4-Tert-butylphenyl)-3-[3-[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(methylamino)purin-9-yl]oxolan-2-yl]methyl-propan-2-ylamino]propyl]urea	Investigative	70676140	C28H42N8O4	554.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)NC)O)O	Ki ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BLA4S9	N-[(6-Methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]-1-propan-2-ylindazole-4-carboxamide	Investigative	54596764	C31H39N7O2	541.7	CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C)C(C)C	IC50 ~ 100000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BOWZ98	1-[3-[[(3R,4S,5R)-3-(6-Aminopurin-9-yl)-4,5-dihydroxycyclopenten-1-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea	Investigative	76328021	C28H40N8O3	536.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2=C[C@H]([C@@H]([C@@H]2O)O)N3C=NC4=C(N=CN=C43)N	Ki ~ 50000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BV61WA	1-((2-(1H-Indol-3-yl)ethyl)amino)-3-(9H-carbazol-9-yl)-propan-2-ol	Investigative	16451230	C25H25N3O	383.5	C1=CC=C2C(=C1)C(=CN2)CCNCC(CN3C4=CC=CC=C4C5=CC=CC=C53)O	IC50 ~ 150000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	BW20ZO	5'-[(3-{[(4-Tert-Butylphenyl)carbamoyl]amino}propyl)(Propan-2-Yl)amino]-5'-Deoxyadenosine	Investigative	56951879	C27H40N8O4	540.7	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)O	Ki ~ 50000 nM	Poor binder
T39519	Lysine N-methyltransferase 1A	D02TVQ	GSK343	Investigative	71268957	C31H39N7O2	541.7	CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CC(=NC=C4)N5CCN(CC5)C)C(C)C	IC50 ~ 100000 nM	Poor binder