TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T40812	Poly [ADP-ribose] polymerase 2	B0MK9O	4-(4-Carbamoylphenoxy)benzamide	Investigative	236501	C14H12N2O3	256.26	C1=CC(=CC=C1C(=O)N)OC2=CC=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	B0R7CZ	IWR-1-endo	Investigative	44483163	C25H19N3O3	409.4	C1[C@@H]2C=C[C@H]1[C@@H]3[C@H]2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6	IC50 ~ 170000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	B0UEY5	Benzyl N-[[4-(8-methyl-4-oxo-1H-quinazolin-2-yl)phenyl]methyl]carbamate	Investigative	136215774	C24H21N3O3	399.4	CC1=C2C(=CC=C1)C(=O)NC(=N2)C3=CC=C(C=C3)CNC(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	B3W7HN	2-Amino-5-[4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]cyclohexyl]pyridine-3-carbonitrile	Investigative	72724967	C23H26N4O2	390.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)C3=CC(=C(N=C3)N)C#N)C4=CC=CC=C4)C	IC50 ~ 170000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	B5VZ2E	N-[(4-Oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenyl-N-(thiophen-2-ylmethyl)propanamide	Investigative	136219322	C22H23N3O3S	409.5	C1COCC2=C1N=C(NC2=O)CN(CC3=CC=CS3)C(=O)CCC4=CC=CC=C4	IC50 = 56400 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	B82KFB	4-(4-Formyl-phenoxy)-benzamide	Investigative	28825277	C14H11NO3	241.24	C1=CC(=CC=C1C=O)OC2=CC=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	B84PNF	N-[4-[(4S)-5,5-Dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]cyclohexyl]-7-fluoro-1,5-naphthyridine-4-carboxamide	Investigative	71681176	C26H27FN4O3	462.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)NC(=O)C3=C4C(=NC=C3)C=C(C=N4)F)C5=CC=CC=C5)C	IC50 ~ 170000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	B96SDF	4-Methoxybenzamide	Investigative	76959	C8H9NO2	151.16	COC1=CC=C(C=C1)C(=O)N	IC50 = 77000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BD1EV4	1,2-Dihydro-2-(4-isopropylphenyl)-4(3H)-quinazolinone	Investigative	4163640	C17H18N2O	266.34	CC(C)C1=CC=C(C=C1)C2NC3=CC=CC=C3C(=O)N2	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BEM90P	N-[3-Chloranyl-4-[[4-(4-Methoxyphenyl)oxan-4-Yl]methylcarbamoyl]phenyl]furan-2-Carboxamide	Investigative	89649815	C25H25ClN2O5	468.9	COC1=CC=C(C=C1)C2(CCOCC2)CNC(=O)C3=C(C=C(C=C3)NC(=O)C4=CC=CO4)Cl	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BEW1B3	4-[(2-Fluorophenyl)methoxy]benzamide	Investigative	8607850	C14H12FNO2	245.25	C1=CC=C(C(=C1)COC2=CC=C(C=C2)C(=O)N)F	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BG25KO	(4s)-3-{trans-4-[6-Amino-5-(Pyrimidin-2-Yl)pyridin-3-Yl]cyclohexyl}-5,5-Dimethyl-4-Phenyl-1,3-Oxazolidin-2-One	Investigative	71660496	C26H29N5O2	443.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)C3=CC(=C(N=C3)N)C4=NC=CC=N4)C5=CC=CC=C5)C	IC50 ~ 170000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BG75NL	2-(4-Tert-Butylphenyl)-2,3-dihydroquinazoline-4(1H)-one	Investigative	4826644	C18H20N2O	280.4	CC(C)(C)C1=CC=C(C=C1)C2NC3=CC=CC=C3C(=O)N2	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BJER35	2-(4-Bromophenyl)-3,4-Dihydroquinazolin-4-One	Investigative	135421564	C14H9BrN2O	301.14	C1=CC=C2C(=C1)C(=O)NC(=N2)C3=CC=C(C=C3)Br	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BS84KD	4-(4-Carbamoylphenoxy)benzoic acid	Investigative	28825295	C14H11NO4	257.24	C1=CC(=CC=C1C(=O)N)OC2=CC=C(C=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BSL3C5	1-[3-[4-(2-Chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxidanylidene-3~{H}-benzimidazole-5-carbonitrile	Investigative	131801402	C24H17ClN8O	468.9	C1C(CC1N2C3=C(C=C(C=C3)C#N)NC2=O)C4=NN=C(N4C5=CC=CC=C5Cl)C6=NC=NC=C6	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BW6IR7	(4s)-3-{4-[6-Amino-5-(Pyrimidin-2-Yl)pyridin-3-Yl]phenyl}-5,5-Dimethyl-4-Phenyl-1,3-Oxazolidin-2-One	Investigative	72193935	C26H23N5O2	437.5	CC1([C@@H](N(C(=O)O1)C2=CC=C(C=C2)C3=CC(=C(N=C3)N)C4=NC=CC=N4)C5=CC=CC=C5)C	IC50 ~ 170000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BX6NZ3	4-[(3Ar,4r,7s,7as)-1,3-Dioxooctahydro-2h-4,7-Methanoisoindol-2-Yl]-N-(Quinolin-8-Yl)benzamide	Investigative	56587957	C25H21N3O3	411.5	C1C[C@H]2C[C@@H]1[C@@H]3[C@H]2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6	IC50 ~ 100000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BY3QL6	1-[4-[(4S)-5,5-Dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]cyclohexyl]-4-fluoro-2-oxo-3H-benzimidazole-5-carbonitrile	Investigative	71681330	C25H25FN4O3	448.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)N3C4=C(C(=C(C=C4)C#N)F)NC3=O)C5=CC=CC=C5)C	IC50 ~ 170000 nM	Poor binder
T40812	Poly [ADP-ribose] polymerase 2	BZQ31Y	N-{4-[(2-Chlorophenyl)(Pyrimidin-4-Yl)carbamoyl]phenyl}-4-Methoxybenzamide	Investigative	105539834	C25H19ClN4O3	458.9	COC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)C(=O)N(C3=NC=NC=C3)C4=CC=CC=C4Cl	IC50 ~ 100000 nM	Poor binder