TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T41145 Bromodomain and PHD finger containing 1 B18EOM Chembl4277110 Investigative 27853996 C24H25N5O3 431.5 CCN1C2=C(C=C(C=C2)C(=O)N(C)CC3=C(N(N=C3C)C4=CC=CC=C4)C)NC(=O)C1=O IC50 ~ 100000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 B2ISO1 4-Cyano-N-(1,3-diethyl-2-oxoquinolin-6-yl)benzenesulfonamide Investigative 137636309 C20H19N3O3S 381.4 CCC1=CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)C#N)N(C1=O)CC IC50 ~ 100000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 B5Y4BO Chembl4289781 Investigative 45873751 C24H25N5O3 431.5 CCN1C2=C(C=C(C=C2)C(=O)NC(C)C3=C(N(N=C3)C4=CC=C(C=C4)C)C)NC(=O)C1=O IC50 ~ 100000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 B7G2NK Chembl4213809 Investigative 137321203 C26H27N5O3 457.5 CC(=O)N1[C@H](CN(C2=C1C=CC(=C2)C3=CN=C(N=C3)C(=O)N)CC4=CC=CC=C4CO)C5CC5 IC50 ~ 100000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 B8Q1ST Chembl4281624 Investigative 42929656 C16H22N4O2S 334.4 CC1CCCN(C1)CC2=CSC(=N2)NC(=O)C3=C(ON=C3C)C IC50 = 195000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 BC0S1Z Chembl4291947 Investigative 27331320 C24H25N5O3 431.5 CCN1C2=C(C=C(C=C2)C(=O)NCC3=C(N(N=C3C)CC4=CC=CC=C4)C)NC(=O)C1=O IC50 ~ 100000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 BITE42 Chembl4280229 Investigative 22110019 C27H23N5O3 465.5 CCN1C2=C(C=C(C=C2)C(=O)NCC3=CN(N=C3C4=CC=CC=C4)C5=CC=CC=C5)NC(=O)C1=O IC50 ~ 50000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 BKW7O3 Chembl4284079 Investigative 42923164 C20H16FN5O3 393.4 CN1C=CN=C1C(C2=CC(=CC=C2)F)NC(=O)C3=CC4=C(C=C3)NC(=O)C(=O)N4 IC50 ~ 50000 nM Poor binder T41145 Bromodomain and PHD finger containing 1 BVW76Y Chembl4288422 Investigative 47035502 C20H19N7O2 389.4 CCN1C2=C(C=C(C=C2)C(=O)NCC3=CN=C(C=C3)N4C=NC=N4)N=C(C1=O)C IC50 ~ 50000 nM Poor binder