TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T46465	Plasmodium Plasmepsin 2	B4E1BT	(3S,4S)-4-((2S,3R)-2-(2-(4-(2-((2S)-1-((2R)-6-Amino-1-(4-(6-methoxyquinolin-8-ylamino)pentylamino)-1-oxohexan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-2-oxoethyl)phenyl)acetamido)-3-methylpentanamido)-N-butyl-3-hydroxy-6-methylheptanamide	Investigative	45268544	C54H85N9O8	988.3	CCCCNC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](C(C)CC)NC(=O)CC1=CC=C(C=C1)CC(=O)N[C@@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)NCCCC(C)NC2=C3C(=CC(=C2)OC)C=CC=N3)O	IC50 = 135000 nM	Poor binder
T46465	Plasmodium Plasmepsin 2	BSDY81	N-[(2S,3S)-5-(Butylamino)-3-hydroxy-5-oxo-1-phenylpentan-2-yl]-4-[2-(2-phenylethoxy)ethyl]-1-[3-(3,4,5-trimethoxyphenyl)propanoyl]piperazine-2-carboxamide	Investigative	44338421	C42H58N4O8	746.9	CCCCNC(=O)C[C@@H]([C@H](CC1=CC=CC=C1)NC(=O)C2CN(CCN2C(=O)CCC3=CC(=C(C(=C3)OC)OC)OC)CCOCCC4=CC=CC=C4)O	IC50 ~ 65000 nM	Poor binder
T46465	Plasmodium Plasmepsin 2	BUYN67	6-{3-((1S,2S)-1-Benzyl-3-butylcarbamoyl-2-hydroxy-propylcarbamoyl)-4-[3-(3,4,5-trimethoxy-phenyl)-propionyl]-piperazin-1-yl}-6-oxo-hexanoic acid ethyl ester	Investigative	44338599	C40H58N4O10	754.9	CCCCNC(=O)C[C@@H]([C@H](CC1=CC=CC=C1)NC(=O)C2CN(CCN2C(=O)CCC3=CC(=C(C(=C3)OC)OC)OC)C(=O)CCCCC(=O)OCC)O	IC50 ~ 100000 nM	Poor binder
T46465	Plasmodium Plasmepsin 2	D03NKE	6-bromo-2'-de-N-methylaplysinopsin	Investigative	135474338	C13H11BrN4O	319.16	.	IC50 = 53000 nM	Poor binder