TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T51385 G-protein coupled receptor 120 B02NRH 3-[2-Fluoro-4-[2-[3-(2-methylsulfonylethoxymethyl)phenyl]ethynyl]phenyl]propanoic acid Investigative 73345870 C21H21FO5S 404.5 CS(=O)(=O)CCOCC1=CC(=CC=C1)C#CC2=CC(=C(C=C2)CCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B1H4LD 3-[2-Fluoro-4-[2-[2-(2-methylsulfonylethoxymethyl)phenyl]ethynyl]phenyl]propanoic acid Investigative 73356514 C21H21FO5S 404.5 CS(=O)(=O)CCOCC1=CC=CC=C1C#CC2=CC(=C(C=C2)CCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B1QK4C 10-Hydroxylauric acid Investigative 10176767 C12H24O3 216.32 CCC(CCCCCCCCC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B1X8AY 3-[4-(3-Methylbut-3-en-1-ynyl)phenyl]propanoic acid Investigative 127030715 C14H14O2 214.26 CC(=C)C#CC1=CC=C(C=C1)CCC(=O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B2BZ0A 11-Hydroxylauric acid Investigative 169433 C12H24O3 216.32 CC(CCCCCCCCCC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B2Y9QK 6-Hydroxydodecanoic acid Investigative 37289 C12H24O3 216.32 CCCCCCC(CCCCC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B43UVK 3-[4-[2-(Cyclohexen-1-yl)ethynyl]phenyl]propanoic acid Investigative 127030714 C17H18O2 254.32 C1CCC(=CC1)C#CC2=CC=C(C=C2)CCC(=O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B4EKA7 2-(3-Fluoro-5-phenylmethoxyphenyl)-3H-1,2-benzothiazole 1,1-dioxide Investigative 67134965 C20H16FNO3S 369.4 C1C2=CC=CC=C2S(=O)(=O)N1C3=CC(=CC(=C3)F)OCC4=CC=CC=C4 EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B5PD8U 3-[5-(2-Phenylethynyl)pyridin-2-yl]propanoic acid Investigative 71655225 C16H13NO2 251.28 C1=CC=C(C=C1)C#CC2=CN=C(C=C2)CCC(=O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B6HMR9 3-[2-Fluoro-4-[2-[3-(3-methylsulfonylpropoxymethyl)phenyl]ethynyl]phenyl]propanoic acid Investigative 73348895 C22H23FO5S 418.5 CS(=O)(=O)CCCOCC1=CC(=CC=C1)C#CC2=CC(=C(C=C2)CCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B8YH7X 3-[2-Fluoro-4-[2-[2-(methylsulfonylmethyl)phenyl]ethynyl]phenyl]propanoic acid Investigative 66562387 C19H17FO4S 360.4 CS(=O)(=O)CC1=CC=CC=C1C#CC2=CC(=C(C=C2)CCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 B9T1QH 3-[2-Fluoro-4-(3-methylbut-3-en-1-ynyl)phenyl]propanoic acid Investigative 66562287 C14H13FO2 232.25 CC(=C)C#CC1=CC(=C(C=C1)CCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BD3ZM4 3-[6-(2-Phenylethynyl)pyridin-3-yl]propanoic acid Investigative 71655226 C16H13NO2 251.28 C1=CC=C(C=C1)C#CC2=NC=C(C=C2)CCC(=O)O EC50 = 91201.08 nM Poor binder T51385 G-protein coupled receptor 120 BFQL84 3-[4-[2-(1-Hydroxycyclohexyl)ethynyl]phenyl]propanoic acid Investigative 127030713 C17H20O3 272.34 C1CCC(CC1)(C#CC2=CC=C(C=C2)CCC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BG7T5M 9-Hydroxy-dodecanoic acid Investigative 5312744 C12H24O3 216.32 CCCC(CCCCCCCC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BG8RK7 7-Hydroxylauric acid Investigative 5312743 C12H24O3 216.32 CCCCCC(CCCCCC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BGY50X 3-[2-Fluoro-4-[2-[2-(3-methylsulfonylpropoxymethyl)phenyl]ethynyl]phenyl]propanoic acid Investigative 73354950 C22H23FO5S 418.5 CS(=O)(=O)CCCOCC1=CC=CC=C1C#CC2=CC(=C(C=C2)CCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BH3X9B 3-[2-Fluoro-4-[2-[3-(methylsulfonylmethyl)phenyl]ethynyl]phenyl]propanoic acid Investigative 66562388 C19H17FO4S 360.4 CS(=O)(=O)CC1=CC(=CC=C1)C#CC2=CC(=C(C=C2)CCC(=O)O)F EC50 = 64565.42 nM Poor binder T51385 G-protein coupled receptor 120 BL7S6F 3-[4-(2-Cyclopropylethynyl)phenyl]propanoic acid Investigative 127033354 C14H14O2 214.26 C1CC1C#CC2=CC=C(C=C2)CCC(=O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BLT36V 5-Hydroxydodecaneoic acid sodium salt Investigative 102338889 C12H23NaO3 238.3 CCCCCCCC(CCCC(=O)[O-])O.[Na+] EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BM2NP0 3-[2-Fluoro-4-[(Z)-5-hydroxy-3-methylpent-3-en-1-ynyl]phenyl]propanoic acid Investigative 66562391 C15H15FO3 262.28 C/C(=C/CO)/C#CC1=CC(=C(C=C1)CCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BP5O7Y 3-(4-{[(4-Phenylphenyl)methyl]amino}phenyl)propanoic acid Investigative 24825484 C22H21NO2 331.4 C1=CC=C(C=C1)C2=CC=C(C=C2)CNC3=CC=C(C=C3)CCC(=O)O EC50 = 58884.37 nM Poor binder T51385 G-protein coupled receptor 120 BP5VM0 Chembl4246529 Investigative 145982616 C24H26F4O5 470.5 COC1CC(C1)OC2=CC(=C(C(=C2)F)F)C3=CC(=C(C(=C3)F)OCCCCCCC(=O)O)F EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BT5OE3 3-[4-[(2-Phenylphenyl)methylamino]phenyl]propanoic acid Investigative 54582150 C22H21NO2 331.4 C1=CC=C(C=C1)C2=CC=CC=C2CNC3=CC=C(C=C3)CCC(=O)O EC50 = 51286.14 nM Poor binder T51385 G-protein coupled receptor 120 BTGX86 3-(4-Ethynylphenyl)propanoic acid Investigative 54757519 C11H10O2 174.2 C#CC1=CC=C(C=C1)CCC(=O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BUQ0A9 3-[4-(Benzylamino)phenyl]propanoic acid Investigative 23346507 C16H17NO2 255.31 C1=CC=C(C=C1)CNC2=CC=C(C=C2)CCC(=O)O EC50 = 57543.99 nM Poor binder T51385 G-protein coupled receptor 120 BV07OL 3-[4-[[3-(2,6-Dimethylphenyl)phenyl]methylamino]-2-fluorophenyl]propanoic acid Investigative 60195040 C24H24FNO2 377.4 CC1=C(C(=CC=C1)C)C2=CC=CC(=C2)CNC3=CC(=C(C=C3)CCC(=O)O)F EC50 = 93325.43 nM Poor binder T51385 G-protein coupled receptor 120 BVN2Q6 Sodium 4-hydroxydodecanoate Investigative 23699039 C12H23NaO3 238.3 CCCCCCCCC(CCC(=O)[O-])O.[Na+] EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 BY6KI8 8-Hydroxydodecanoic acid Investigative 14454530 C12H24O3 216.32 CCCCC(CCCCCCC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 D03JPL 12-hydroxylauric acid Investigative 79034 C12H24O3 216.32 C(CCCCCC(=O)O)CCCCCO EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 D0T2CG 3-hydroxylauric acid Investigative 94216 C12H24O3 216.32 CCCCCCCCCC(CC(=O)O)O EC50 ~ 100000 nM Poor binder T51385 G-protein coupled receptor 120 D0T4BP 2-hydroxylauric acid Investigative 97783 C12H24O3 216.32 CCCCCCCCCCC(C(=O)O)O EC50 ~ 100000 nM Poor binder