TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T54771	Sodium/glucose cotransporter 1	B0W7GE	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-7-methoxy-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	90644321	C20H22ClN3O7	451.9	COC1=CC2=NN(C(=O)N2C=C1)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B1H0GZ	(2S,3R,4R,5S,6R)-2-(4-Chloro-2-((2,2-difluoropropoxy)methyl)-5-(4-ethylbenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol	Investigative	25169515	C25H31ClF2O6	501	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2Cl)COCC(C)(F)F)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	IC50 = 140000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B1P4CZ	CID 11718001	Investigative	11718001	C23H30O5	386.5	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2)C)[C@@]3(C[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)O	IC50 ~ 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B27KPR	(1R,2S,3R,4R,6R)-4-(Hydroxymethyl)-6-[2-[[4-(trifluoromethyl)phenyl]methyl]phenoxy]cyclohexane-1,2,3-triol	Investigative	11517178	C21H23F3O5	412.4	C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1OC2=CC=CC=C2CC3=CC=C(C=C3)C(F)(F)F)O)O)O)CO	IC50 = 57000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B2HX8V	1-[3,5-Dibromo-2,4-dihydroxy-6-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(3,5-dibromo-4-hydroxyphenyl)propan-1-one	Investigative	71719684	C21H20Br4O10	752	C1=C(C=C(C(=C1Br)O)Br)CCC(=O)C2=C(C(=C(C(=C2O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O)Br)O)Br)O	Ki = 93100 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B3AM4N	(2S,3R,4R,5S,6R)-2-(4-Chloro-5-(4-ethylbenzyl)-2-((2,2,2-trifluoroethoxy)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol	Investigative	46906391	C24H28ClF3O6	504.9	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2Cl)COCC(F)(F)F)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	IC50 = 134000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B3EHU6	CID 11704386	Investigative	11704386	C24H32O6	416.5	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2)OCC)[C@@]3(C[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)O	IC50 ~ 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B3Q1TC	(2S,3R,4R,5S,6R)-2-(2-(Allyloxymethyl)-4-chloro-5-(4-ethylbenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol	Investigative	25168565	C25H31ClO6	463	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2Cl)COCC=C)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	IC50 = 91000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B3QH9Z	(E)-3-(4-Phenylmethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one	Investigative	129237363	C22H18O5	362.4	C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C/C(=O)C3=C(C=C(C=C3O)O)O	IC50 = 52600 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B50PJV	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-7-(hydroxymethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467977	C20H22ClN3O7	451.9	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=CC(=CC4=N3)CO)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B5YP6C	6-Bromo-2-[[2-chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467763	C19H19BrClN3O6	500.7	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=C(C=CC4=N3)Br)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B67NPQ	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-6-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467553	C20H22ClN3O6	435.9	CC1=CN2C(=NN(C2=O)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl)C=C1	IC50 = 67442 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B6D2KY	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridine-3-thione	Investigative	53467760	C19H20ClN3O5S	437.9	C1=CC2=NN(C(=S)N2C=C1)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 ~ 73192 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B7AT6N	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-6-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467764	C19H19ClFN3O6	439.8	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=C(C=CC4=N3)F)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B7EGV6	(2S,3R,4R,5R)-2-[4-Chloro-3-[(6-methoxynaphthalen-2-yl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73354081	C24H25ClO6	444.9	COC1=CC2=C(C=C1)C=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@H](O4)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B7L8EQ	Methyl (14E)-19-[(acetyloxy)methyl]-14-ethylidene-6-methoxy-2-methyl-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate	Investigative	46229158	C25H30N2O6	454.5	C/C=C\\1/CN2[C@H]3C[C@@H]1[C@@]([C@@]45[C@@]3(N(C6=C4C=C(C=C6)OC)C)O[C@H]2C5)(COC(=O)C)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B7U2ZF	CID 53468204	Investigative	53468204	C23H25ClN2O7	476.9	CN1C(=O)CN(C1=O)C2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 = 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B8HR4A	(2S,3R,4R,5R)-2-[4-Chloro-3-[(4-methylsulfanylphenyl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73348017	C20H23ClO5S	410.9	CSC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B8QGL2	6-Chloro-2-[[2-chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467975	C20H21Cl2N3O6	470.3	CC1=CC2=NN(C(=O)N2C=C1Cl)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B93GMD	CID 53468203	Investigative	53468203	C25H29ClN2O7	505	CC1(C(=O)N(C(=O)N1C2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl)C)C	IC50 = 83060 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B94TZV	(3S,3'R,4'S,5'S,6'R)-6'-(Aminomethyl)-6-chloro-7-[(4-ethylphenyl)methyl]spiro[1H-2-benzofuran-3,2'-oxane]-3',4',5'-triol	Investigative	45488040	C22H26ClNO5	419.9	CCC1=CC=C(C=C1)CC2=C(C=CC3=C2CO[C@@]34[C@@H]([C@H]([C@@H]([C@H](O4)CN)O)O)O)Cl	IC50 ~ 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B9EC8V	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-5-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	90644323	C20H22ClN3O6	435.9	CC1=CC=CC2=NN(C(=O)N12)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B9T1HB	(1R,2R,3S,4S,6R)-4-[2-Ethoxy-5-(4-ethylbenzyl)phenyl]-6-(hydroxymethyl)cyclohexane-1,2,3-triol	Investigative	11553111	C24H32O5	400.5	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2)OCC)[C@@H]3C[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO	IC50 ~ 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	B9YF8L	CID 11596174	Investigative	11596174	C23H30O5	386.5	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2)OC)[C@@H]3C[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO	IC50 = 73000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BA9IZ8	(2S,3R,4R,5R)-2-[4-Chloro-3-[(4-methoxyphenyl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73354079	C20H23ClO6	394.8	COC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)Cl	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BDE07C	8-Chloro-2-[[2-chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	90644324	C19H19Cl2N3O6	456.3	C1=CN2C(=NN(C2=O)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl)C(=C1)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BDY1A3	CID 11509608	Investigative	11509608	C23H30O6	402.5	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2)OC)[C@@]3(C[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)O	IC50 ~ 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BEW86O	1-[2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-3-oxo-[1,2,4]triazolo[4,3-a]pyridin-6-yl]cyclopropane-1-carbonitrile	Investigative	58446369	C23H23ClN4O6	486.9	C1CC1(C#N)C2=CN3C(=NN(C3=O)CC4=C(C=CC(=C4)[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)Cl)C=C2	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BEXK92	7-Chloro-2-[[2-chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467555	C19H19Cl2N3O6	456.3	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=CC(=CC4=N3)Cl)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BFB1O2	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-6-(hydroxymethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467759	C20H22ClN3O7	451.9	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=C(C=CC4=N3)CO)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BG9R4N	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467762	C20H22ClN3O6	435.9	CC1=CC2=NN(C(=O)N2C=C1)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 = 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BGW0U3	(2R,3R,4R,5S)-2-[(1R)-1,2-Dihydroxyethyl]-5-[3-[(4-ethoxyphenyl)methyl]-4-methylphenyl]oxolane-3,4-diol	Investigative	73348014	C22H28O6	388.5	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)C	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BI2U9E	Methyl (14E)-19-[(benzyloxy)methyl]-14-ethylidene-6-methoxy-2-methyl-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate	Investigative	46229160	C30H34N2O5	502.6	C/C=C\\1/CN2[C@H]3C[C@@H]1[C@@]([C@@]45[C@@]3(N(C6=C4C=C(C=C6)OC)C)O[C@H]2C5)(COCC7=CC=CC=C7)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BIVH86	(1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxyphenyl]-1-thio-D-glucitol	Investigative	46204821	C22H28O6S	420.5	CCOC1=CC=C(C=C1)CC2=CC(=C(C=C2)OC)[C@H]3[C@@H]([C@H]([C@@H]([C@H](S3)CO)O)O)O	IC50 = 100000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BJSI23	US8575114, III-5	Investigative	58446361	C25H29ClN2O7	505	CC1(C(=O)N(C(=O)N1C2=CC=C(C=C2)CC3=C(C=CC(=C3)C4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl)C)C	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BK3U5T	2',4',6'-Trihydroxy-4-methoxychalcone	Investigative	13990811	C16H14O5	286.28	COC1=CC=C(C=C1)/C=C/C(=O)C2=C(C=C(C=C2O)O)O	IC50 = 50900 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BNOU02	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-6-(2-hydroxyethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467978	C21H24ClN3O7	465.9	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=C(C=CC4=N3)CCO)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BO5WZ9	3-Amino-5-[3-[2,4-dihydroxy-6-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-oxopropyl]-2-hydroxybenzenesulfonic acid	Investigative	71717245	C21H25NO13S	531.5	C1=C(C=C(C(=C1N)O)S(=O)(=O)O)CCC(=O)C2=C(C=C(C=C2O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O)O)O	Ki = 152000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BOHQ78	(2S,3R,4R,5S,6R)-2-[4-Chloro-3-([1,2,4]triazolo[1,5-a]pyridin-6-ylmethyl)phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	53467979	C19H20ClN3O5	405.8	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CN4C(=NC=N4)C=C3)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BP9Y4G	4-[5-[3-[2,4-Dihydroxy-6-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-oxopropyl]-2-hydroxyanilino]-4-oxobutanoic acid	Investigative	71717246	C25H29NO13	551.5	C1=CC(=C(C=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O)O)O)NC(=O)CCC(=O)O)O	Ki = 116000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BPBG92	(2R,3R,4R,5S)-2-[(1R)-1,2-Dihydroxyethyl]-5-[3-[(4-ethylphenyl)methyl]-4-methylphenyl]oxolane-3,4-diol	Investigative	73346536	C22H28O5	372.5	CCC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O)C	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BPIM83	(2S,3R,4R,5R)-2-[4-Chloro-2-methoxy-5-[(4-propan-2-ylphenyl)methyl]phenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73354078	C23H29ClO6	436.9	CC(C)C1=CC=C(C=C1)CC2=CC(=C(C=C2Cl)OC)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BQ27LN	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-7-(2,2,2-trifluoroethoxy)-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	90644322	C21H21ClF3N3O7	519.9	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=CC(=CC4=N3)OCC(F)(F)F)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BQN5I1	(2R,3R,4R,5S,6R)-2-[3-[[4-[[(1R,5S)-3-Bicyclo[3.1.0]hexanyl]oxy]phenyl]methyl]-4-chlorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol	Investigative	118205094	C25H29ClO6	460.9	C1[C@H]2[C@@H]1CC(C2)OC3=CC=C(C=C3)CC4=C(C=CC(=C4)[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)Cl	IC50 = 75465.18 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BR27HY	(2S,3R,4R,5S,6R)-2-(4-Chloro-5-(4-ethylbenzyl)-2-((3-hydroxypropoxy)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol	Investigative	25168849	C25H33ClO7	481	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2Cl)COCCCO)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	IC50 = 103000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BSO5P3	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467556	C20H19ClF3N3O6	489.8	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=C(C=CC4=N3)C(F)(F)F)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BTC6W4	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-7-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467554	C20H19ClF3N3O6	489.8	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=CC(=CC4=N3)C(F)(F)F)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BUW06H	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-8-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	90644325	C19H19ClFN3O6	439.8	C1=CN2C(=NN(C2=O)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl)C(=C1)F	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BVX35M	N-[5-[3-[2,4-Dihydroxy-6-[(2S,3S,4S,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-oxopropyl]-2-hydroxyphenyl]-5-(dimethylamino)naphthalene-1-sulfonamide	Investigative	71719076	C33H36N2O12S	684.7	CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NC3=C(C=CC(=C3)CCC(=O)C4=C(C=C(C=C4O[C@H]5[C@H]([C@H]([C@@H]([C@@H](O5)CO)O)O)O)O)O)O	Ki = 94300 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BWLY57	Methyl (14E)-14-ethylidene-6-methoxy-2-methyl-19-[(propanoyloxy)methyl]-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate	Investigative	46229159	C26H32N2O6	468.5	CCC(=O)OC[C@]1([C@H]\\2C[C@H]3[C@@]45[C@@]1(C[C@@H](N3C/C2=C/C)O4)C6=C(N5C)C=CC(=C6)OC)C(=O)OC	IC50 = 97000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BX6QA4	(2S,3R,4R,5R)-2-[4-Chloro-5-[(4-ethoxyphenyl)methyl]-2-methoxyphenyl]-5-[(1R)-1,2-dihydroxyethyl]oxolane-3,4-diol	Investigative	73357149	C22H27ClO7	438.9	CCOC1=CC=C(C=C1)CC2=CC(=C(C=C2Cl)OC)[C@H]3[C@@H]([C@H]([C@H](O3)[C@@H](CO)O)O)O	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BXA80N	(2R,3R,4R,5S)-2-[(1R)-1,2-Dihydroxyethyl]-5-[4-methyl-3-[(4-propan-2-ylphenyl)methyl]phenyl]oxolane-3,4-diol	Investigative	73354077	C23H30O5	386.5	CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@H](O2)[C@@H](CO)O)O)O)CC3=CC=C(C=C3)C(C)C	EC50 ~ 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BXU78P	2-[[2-Chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467552	C19H20ClN3O6	421.8	C1=CC2=NN(C(=O)N2C=C1)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl	IC50 ~ 90000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BY3NW7	6-Chloro-2-[[2-chloro-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one	Investigative	53467761	C19H19Cl2N3O6	456.3	C1=CC(=C(C=C1[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C(=O)N4C=C(C=CC4=N3)Cl)Cl	IC50 = 61159 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BY50VQ	4-[[(3S,3'R,4'S,5'S,6'R)-3',4',5'-Trihydroxy-6'-(hydroxymethyl)spiro[1H-2-benzofuran-3,2'-oxane]-5-yl]methyl]benzonitrile	Investigative	57556431	C21H21NO6	383.4	C1C2=C(C=C(C=C2)CC3=CC=C(C=C3)C#N)[C@@]4(O1)[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O	IC50 = 81487 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BYJL74	Methyl (14E)-14-ethylidene-6-hydroxy-2-methyl-19-{[(3,4,5-trihydroxyphenyl)carbonyloxy]methyl}-18-oxa-2,12-diazahexacyclo[9.6.1.1^{9,15}.0^{1,9}.0^{3,8}.0^{12,17}]nonadeca-3(8),4,6-triene-19-carboxylate	Investigative	46229154	C29H30N2O9	550.6	C/C=C\\1/CN2[C@H]3C[C@@H]1[C@@]([C@@]45[C@@]3(N(C6=C4C=C(C=C6)O)C)O[C@H]2C5)(COC(=O)C7=CC(=C(C(=C7)O)O)O)C(=O)OC	IC50 = 50000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BYWR60	(2S,3R,4R,5S,6R)-2-(4-Chloro-5-(4-ethylbenzyl)-2-((2-hydroxypropoxy)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol	Investigative	25168568	C25H33ClO7	481	CCC1=CC=C(C=C1)CC2=CC(=C(C=C2Cl)COCC(C)O)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O	IC50 = 60000 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	BZ39FM	5-[[2-Chloro-5-[(3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]phenyl]methyl]furo[3,2-c]pyridin-4-one	Investigative	58446355	C20H20ClNO7	421.8	C1=CC(=C(C=C1C2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CN3C=CC4=C(C3=O)C=CO4)Cl	IC50 = 71535 nM	Poor binder
T54771	Sodium/glucose cotransporter 1	D0HD2G	phloretin	Investigative	4788	C15H14O5	274.27	C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O	Ki = 86000 nM	Poor binder