TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T55922	S-adenosylmethionine decarboxylase proenzyme	B0NSO4	(2R,3R,4S,5R)-2-(6-Amino-8-methyl-9H-purin-9-yl)-5-{[(2-aminoethyl)(methyl)amino]methyl}oxolane-3,4-diol	Investigative	25233591	C14H23N7O3	337.38	CC1=NC2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CN(C)CCN)O)O)N	IC50 = 88000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B1G7JR	4-N-(3-Chloro-5-naphthalen-2-ylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137632834	C21H17ClN4	360.8	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC4=CC=CC=C4C=C3)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B1SRL6	4-N-(3,5-Dichlorophenyl)-6-morpholin-4-ylpyrimidine-2,4-diamine	Investigative	137632229	C14H15Cl2N5O	340.2	C1COCCN1C2=NC(=NC(=C2)NC3=CC(=CC(=C3)Cl)Cl)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B1T6QD	2-N-(3,5-Dichlorophenyl)pyridine-2,4-diamine	Investigative	61710896	C11H9Cl2N3	254.11	C1=CN=C(C=C1N)NC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B27LQP	4-[3-[(2-Amino-6-methylpyrimidin-4-yl)amino]-5-chlorophenyl]phenol	Investigative	137653360	C17H15ClN4O	326.8	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC=C(C=C3)O)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B2BH7T	N-(3,5-Dimethylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	19754189	C13H16N4	228.29	CC1=CC(=CC(=C1)NC2=NC(=NC(=C2)C)N)C	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B2EJ0Y	4-N-[3-Chloro-5-(4-methylphenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137659429	C18H17ClN4	324.8	CC1=CC=C(C=C1)C2=CC(=CC(=C2)Cl)NC3=NC(=NC(=C3)C)N	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B38CXL	4-N-[3-[3,5-Bis(trifluoromethyl)phenyl]-5-chlorophenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137653057	C19H13ClF6N4	446.8	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B39MQZ	4-N-[3-Chloro-5-(3,4-dichlorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137652324	C17H13Cl3N4	379.7	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC(=C(C=C3)Cl)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B3GK9W	6-Chloro-4-N-(3,5-dichlorophenyl)pyrimidine-2,4-diamine	Investigative	388060	C10H7Cl3N4	289.5	C1=C(C=C(C=C1Cl)Cl)NC2=CC(=NC(=N2)N)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B3PM2K	4-N-(3,5-Difluorophenyl)-6-methylpyrimidine-2,4-diamine	Investigative	80761654	C11H10F2N4	236.22	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)F)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B4G2ST	5-[(2-Amino-6-methylpyrimidin-4-yl)amino]-1-N,3-N-bis(3,5-dichlorophenyl)benzene-1,3-dicarboxamide	Investigative	137651239	C25H18Cl4N6O2	576.3	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C(=O)NC3=CC(=CC(=C3)Cl)Cl)C(=O)NC4=CC(=CC(=C4)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B4RW6D	6-Methyl-N~4~-[2-(methylthio)phenyl]-2,4-pyrimidinediamine	Investigative	56919796	C12H14N4S	246.33	CC1=CC(=NC(=N1)N)NC2=CC=CC=C2SC	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B4VRQ9	4-N-[3-Ethyl-5-(4-fluorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137651433	C19H19FN4	322.4	CCC1=CC(=CC(=C1)NC2=NC(=NC(=C2)C)N)C3=CC=C(C=C3)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B54ROY	(3-Amino(4-pyridyl))(3,5-dichlorophenyl)amine	Investigative	29066960	C11H9Cl2N3	254.11	C1=CN=CC(=C1NC2=CC(=CC(=C2)Cl)Cl)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B59WAU	4-N-(3,5-Dichlorophenyl)-6-propan-2-ylpyrimidine-2,4-diamine	Investigative	137657983	C13H14Cl2N4	297.18	CC(C)C1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B5BD4S	4-N-[3-Chloro-5-(pentafluoro-lambda6-sulfanyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137659438	C11H10ClF5N4S	360.73	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)Cl)S(F)(F)(F)(F)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B5HP1V	6-Methyl-4-N-[3-(pentafluoro-lambda6-sulfanyl)phenyl]pyrimidine-2,4-diamine	Investigative	137642459	C11H11F5N4S	326.29	CC1=CC(=NC(=N1)N)NC2=CC(=CC=C2)S(F)(F)(F)(F)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B5RC3U	4-N-(2-Bromophenyl)-6-methylpyrimidine-2,4-diamine	Investigative	240809	C11H11BrN4	279.14	CC1=CC(=NC(=N1)N)NC2=CC=CC=C2Br	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B5VR7J	N~4~-(3-Chloro-2-methylphenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56921749	C12H13ClN4	248.71	CC1=CC(=NC(=N1)N)NC2=C(C(=CC=C2)Cl)C	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B5VY7L	4-N-(3,5-Dichlorophenyl)pyridine-2,4-diamine	Investigative	104032679	C11H9Cl2N3	254.11	C1=CN=C(C=C1NC2=CC(=CC(=C2)Cl)Cl)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B5XW0N	4-N-(3-Fluorophenyl)-6-methylpyrimidine-2,4-diamine	Investigative	56919646	C11H11FN4	218.23	CC1=CC(=NC(=N1)N)NC2=CC(=CC=C2)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B65JXG	4-N-(3,5-Diphenylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137648725	C23H20N4	352.4	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B6E0IL	4-N-(3,5-Dichlorophenyl)-2-N,6-dimethylpyrimidine-2,4-diamine	Investigative	80768523	C12H12Cl2N4	283.15	CC1=CC(=NC(=N1)NC)NC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B6LD5M	6-Methyl-N4-(o-tolyl)pyrimidine-2,4-diamine	Investigative	45097405	C12H14N4	214.27	CC1=CC=CC=C1NC2=NC(=NC(=C2)C)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B6X1CT	4-N-(3,5-Dichlorophenyl)pyrimidine-2,4-diamine	Investigative	80768222	C10H8Cl2N4	255.1	C1=CN=C(N=C1NC2=CC(=CC(=C2)Cl)Cl)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B71POC	N~4~-(2,3-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56922155	C11H10Cl2N4	269.13	CC1=CC(=NC(=N1)N)NC2=C(C(=CC=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B90ZOI	4-N-[3-Chloro-5-(4-chlorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137660314	C17H14Cl2N4	345.2	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC=C(C=C3)Cl)Cl	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B91GZK	4-N-[3-(1-Benzothiophen-2-yl)-5-chlorophenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137634161	C19H15ClN4S	366.9	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC4=CC=CC=C4S3)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B9APW5	Chembl540653	Investigative	118725204	C16H25Br2N7O3S	555.3	C[S+](CCCC(C#N)N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O.Br.[Br-]	IC50 = 50000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B9AV4Y	4-N-[3,5-Dichloro-4-(difluoromethoxy)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137646814	C12H10Cl2F2N4O	335.13	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)OC(F)F)Cl	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B9FB3M	4-N-(3-Chloro-5-pyrimidin-5-ylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137648601	C15H13ClN6	312.76	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CN=CN=C3)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B9IKB4	CID 25233958	Investigative	25233958	C14H22N8O4	366.38	CN(CC/C(=N\\O)/N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O	IC50 = 157000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B9JFN3	N~4~-(4-Chloro-2-methylphenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56920865	C12H13ClN4	248.71	CC1=CC(=NC(=N1)N)NC2=C(C=C(C=C2)Cl)C	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	B9SOK3	4-N-[3-Chloro-5-(4-phenylphenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137640514	C23H19ClN4	386.9	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC=C(C=C3)C4=CC=CC=C4)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BAN5O8	6-N-(3,5-Dichlorophenyl)pyridine-2,6-diamine	Investigative	80647643	C11H9Cl2N3	254.11	C1=CC(=NC(=C1)NC2=CC(=CC(=C2)Cl)Cl)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BB0V1N	4-N-(3-Chloro-5-phenanthren-9-ylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137650445	C25H19ClN4	410.9	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC4=CC=CC=C4C5=CC=CC=C53)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BB7K3U	4-N-(3,5-Dichloro-2,4-difluorophenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137642600	C11H8Cl2F2N4	305.11	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2F)Cl)F)Cl	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BBD8J7	4-N-[3-Chloro-5-(1-methylpyrazol-4-yl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137659106	C15H15ClN6	314.77	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CN(N=C3)C)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BCN72G	N~4~-(5-Chloro-2-methylphenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56920454	C12H13ClN4	248.71	CC1=C(C=C(C=C1)Cl)NC2=NC(=NC(=C2)C)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BD5N0A	5-[(2-Amino-6-methylpyrimidin-4-yl)amino]benzene-1,3-dicarboxylic acid	Investigative	137655212	C13H12N4O4	288.26	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C(=O)O)C(=O)O	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BD8R1Z	4-N-[3-Chloro-5-[4-(dimethylamino)phenyl]phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137660126	C19H20ClN5	353.8	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC=C(C=C3)N(C)C)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BDO9W6	4-N-[4-(3,5-Dichlorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137662328	C17H14Cl2N4	345.2	CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)C3=CC(=CC(=C3)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BDOH70	6-Methyl-N~4~-[4-(trifluoromethyl)phenyl]-2,4-pyrimidinediamine	Investigative	56921808	C12H11F3N4	268.24	CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)C(F)(F)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BE7B6O	4-N-(3,5-Dichloro-4-fluorophenyl)-6-methylpyrimidine-2,4-diamine	Investigative	113977178	C11H9Cl2FN4	287.12	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)F)Cl	IC50 ~ 160000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BEQS54	4-N-(3-Bromo-5-chlorophenyl)-2-methylpyrimidine-4,6-diamine	Investigative	137634051	C11H10BrClN4	313.58	CC1=NC(=CC(=N1)NC2=CC(=CC(=C2)Br)Cl)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BF18XC	N-(3,5-Dichlorophenyl)-6-methylpyrimidin-4-amine	Investigative	137645098	C11H9Cl2N3	254.11	CC1=CC(=NC=N1)NC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BF96XU	4-N-[3-Chloro-5-[4-chloro-3-(trifluoromethyl)phenyl]phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137653636	C18H13Cl2F3N4	413.2	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC(=C(C=C3)Cl)C(F)(F)F)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BG4DP9	4-N-[3-(1-Benzofuran-2-yl)-5-chlorophenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137651376	C19H15ClN4O	350.8	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC4=CC=CC=C4O3)Cl	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BGB5J7	4-N-[3-Bromo-5-(pentafluoro-lambda6-sulfanyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137638905	C11H10BrF5N4S	405.19	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)Br)S(F)(F)(F)(F)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BGL8O2	4-N-(3,5-Dichloro-4-morpholin-4-ylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137642510	C15H17Cl2N5O	354.2	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)N3CCOCC3)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BHV2S3	4-N-(3,5-Ditert-butylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137659420	C19H28N4	312.5	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C(C)(C)C)C(C)(C)C	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BIH6C1	(2R,3R,4S,5R)-2-(6-Amino-8-methylpurin-9-yl)-5-[[3-aminopropyl(methyl)amino]methyl]oxolane-3,4-diol;sulfuric acid	Investigative	44564338	C15H27N7O7S	449.5	CC1=NC2=C(N=CN=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CN(C)CCCN)O)O)N.OS(=O)(=O)O	IC50 = 70000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BIL7F1	2-[(2-Amino-6-methylpyrimidin-4-yl)amino]-4,6-dichlorophenol	Investigative	137635782	C11H10Cl2N4O	285.13	CC1=CC(=NC(=N1)N)NC2=C(C(=CC(=C2)Cl)Cl)O	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BJ1D7K	4-N-(3-Bromo-5-butoxyphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137634646	C15H19BrN4O	351.24	CCCCOC1=CC(=CC(=C1)NC2=NC(=NC(=C2)C)N)Br	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BJG4C5	2-Amino-4-phenylamino-6-methylpyrimidine	Investigative	608203	C11H12N4	200.24	CC1=CC(=NC(=N1)N)NC2=CC=CC=C2	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BKO9T6	N~4~-(2,5-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	239269	C11H10Cl2N4	269.13	CC1=CC(=NC(=N1)N)NC2=C(C=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BL15SF	N~4~-(3,4-Difluorophenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56919856	C11H10F2N4	236.22	CC1=CC(=NC(=N1)N)NC2=CC(=C(C=C2)F)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BL53ND	4-N-[3-(2,1,3-Benzoxadiazol-5-yl)-5-chlorophenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137652349	C17H13ClN6O	352.8	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC4=NON=C4C=C3)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BL9RH5	4-N-[3,5-Bis(trifluoromethyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	100765007	C13H10F6N4	336.24	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BM14ZG	N~4~-(4-Bromo-2-fluorophenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56919816	C11H10BrFN4	297.13	CC1=CC(=NC(=N1)N)NC2=C(C=C(C=C2)Br)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BM28TO	4-N-(3-Bromo-5-ethylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137645795	C13H15BrN4	307.19	CCC1=CC(=CC(=C1)Br)NC2=NC(=NC(=C2)C)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BM9P8W	4-N-[3,5-Dichloro-4-(dimethylamino)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137660942	C13H15Cl2N5	312.19	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)N(C)C)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BN9U4L	N~4~-(4-Chlorophenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	2766291	C11H11ClN4	234.68	CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BO1P5Z	4-N-(3,5-Dichlorophenyl)-4-N,6-dimethylpyrimidine-2,4-diamine	Investigative	137635709	C12H12Cl2N4	283.15	CC1=CC(=NC(=N1)N)N(C)C2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BO56LM	4-N-[3-Chloro-5-(2-chlorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137651822	C17H14Cl2N4	345.2	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC=CC=C3Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BOD07K	Chembl607699	Investigative	118725244	C14H19N7O3S	365.41	C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CSCCC(C#N)N)O)O)N	IC50 = 178600 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BOP65Y	4-N-(3,5-Dichloro-4-piperidin-1-ylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137639930	C16H19Cl2N5	352.3	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)N3CCCCC3)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BP3LM9	Dimethyl 5-[(2-amino-6-methylpyrimidin-4-yl)amino]benzene-1,3-dicarboxylate	Investigative	463012	C15H16N4O4	316.31	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C(=O)OC)C(=O)OC	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BP95RQ	4-N-(3,5-Dichlorophenyl)-2-N,2-N,6-trimethylpyrimidine-2,4-diamine	Investigative	137652443	C13H14Cl2N4	297.18	CC1=CC(=NC(=N1)N(C)C)NC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BQ20OI	4-N-(3,5-Dichlorophenyl)-6-methylpyridine-2,4-diamine	Investigative	137632899	C12H11Cl2N3	268.14	CC1=CC(=CC(=N1)N)NC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BQJ35G	N~4~-[2-Chloro-5-(trifluoromethyl)phenyl]-6-methyl-2,4-pyrimidinediamine	Investigative	56921130	C12H10ClF3N4	302.68	CC1=CC(=NC(=N1)N)NC2=C(C=CC(=C2)C(F)(F)F)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BQO6M8	4-N-(3,5-Dichlorophenyl)pyrimidine-2,4,6-triamine	Investigative	80768610	C10H9Cl2N5	270.12	C1=C(C=C(C=C1Cl)Cl)NC2=NC(=NC(=C2)N)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BR28TZ	4-N-(3,5-Dichloro-4-methylphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137644197	C12H12Cl2N4	283.15	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)C)Cl	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BR2A8V	4-N-[(3,5-Dichlorophenyl)methyl]-6-methylpyrimidine-2,4-diamine	Investigative	137660985	C12H12Cl2N4	283.15	CC1=CC(=NC(=N1)N)NCC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BSC4V6	2'-O,3'-O-Isopropylidene-5'-[[(1R)-4alpha-aminooxy-2-cyclopenten-1beta-yl]thio]-5'-deoxyadenosine	Investigative	15218331	C18H24N6O4S	420.5	CC1(O[C@@H]2[C@H](O[C@H]([C@@H]2O1)N3C=NC4=C(N=CN=C43)N)CS[C@@H]5C[C@H](C=C5)ON)C	Ki = 95200 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BT3CI7	N~4~-(4-Isopropylphenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56923076	C14H18N4	242.32	CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)C(C)C	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BT63YG	2-Amino-4-(3-bromophenyl)amino-6-methylpyrimidine	Investigative	56920121	C11H11BrN4	279.14	CC1=CC(=NC(=N1)N)NC2=CC(=CC=C2)Br	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BTZ2G0	4-N-[3-Chloro-5-(3-chlorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137657088	C17H14Cl2N4	345.2	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC(=CC=C3)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BU4MI2	4-[(2-Amino-6-methylpyrimidin-4-yl)amino]-2,6-dichlorophenol	Investigative	137652753	C11H10Cl2N4O	285.13	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)O)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BUG0M9	4-N-(3,5-Dichlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine	Investigative	114563625	C11H7Cl2F3N4	323.1	C1=C(C=C(C=C1Cl)Cl)NC2=NC(=NC(=C2)C(F)(F)F)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BVTB73	4-N-[3-Bromo-5-(2-methylpropoxy)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137652950	C15H19BrN4O	351.24	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)Br)OCC(C)C	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BW9PF1	6-Methyl-4-N-(3,4,5-trichlorophenyl)pyrimidine-2,4-diamine	Investigative	137637985	C11H9Cl3N4	303.6	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)Cl)Cl	IC50 ~ 63000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BWN0L6	4-(3,5-Dichlorophenyl)sulfanyl-6-methylpyrimidin-2-amine	Investigative	137647022	C11H9Cl2N3S	286.2	CC1=CC(=NC(=N1)N)SC2=CC(=CC(=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BWO92G	4-N-[3-Chloro-5-(3-chloro-4-fluorophenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137650167	C17H13Cl2FN4	363.2	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC(=C(C=C3)F)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BWX5G0	N~4~-(2,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56922551	C11H10Cl2N4	269.13	CC1=CC(=NC(=N1)N)NC2=C(C=C(C=C2)Cl)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BXJ68N	4-N-(3,5-Dichloro-4-phenoxyphenyl)-6-methylpyrimidine-2,4-diamine	Investigative	137635823	C17H14Cl2N4O	361.2	CC1=CC(=NC(=N1)N)NC2=CC(=C(C(=C2)Cl)OC3=CC=CC=C3)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BY16AT	4-N-[3-Chloro-5-(4-methoxyphenyl)phenyl]-6-methylpyrimidine-2,4-diamine	Investigative	137635286	C18H17ClN4O	340.8	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)C3=CC=C(C=C3)OC)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BY1LO4	4-N-(3-Chloro-5-fluorophenyl)-6-methylpyrimidine-2,4-diamine	Investigative	107371081	C11H10ClFN4	252.67	CC1=CC(=NC(=N1)N)NC2=CC(=CC(=C2)Cl)F	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BYGC69	N~4~-(4-Ethylphenyl)-6-methyl-2,4-pyrimidinediamine	Investigative	56921153	C13H16N4	228.29	CCC1=CC=C(C=C1)NC2=NC(=NC(=C2)C)N	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BZ43VD	4-(3-Chlorophenylamino)-6-methylpyrimidin-2-amine	Investigative	240808	C11H11ClN4	234.68	CC1=CC(=NC(=N1)N)NC2=CC(=CC=C2)Cl	IC50 ~ 180000 nM	Poor binder
T55922	S-adenosylmethionine decarboxylase proenzyme	BZV1F4	2-N-(3,5-Dichlorophenyl)-6-methylpyridine-2,4-diamine	Investigative	137658244	C12H11Cl2N3	268.14	CC1=CC(=CC(=N1)NC2=CC(=CC(=C2)Cl)Cl)N	IC50 ~ 180000 nM	Poor binder