TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T56057	Lysine-specific demethylase 6B	B0HR8M	2-[1-(1-Butanoylpyrrolidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191473	C16H19N5O3	329.35	CCCC(=O)N1CCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B13VMI	2-(5-Acetamido-2-Oxidanyl-Phenyl)pyridine-4-Carboxylic Acid	Investigative	135567040	C14H12N2O4	272.26	CC(=O)NC1=CC(=C(C=C1)O)C2=NC=CC(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B17VIJ	2-(4-Chloro-3-hydroxyphenoxy)-3H-pyrido[3,4-d]pyrimidin-4-one	Investigative	136053684	C13H8ClN3O3	289.67	C1=CC(=C(C=C1OC2=NC3=C(C=CN=C3)C(=O)N2)O)Cl	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B1YH3M	Methyl 2-[4-[[4-[(1S,2R)-2-aminocyclopropyl]phenyl]carbamoyl]pyridin-2-yl]pyridine-4-carboxylate;hydrochloride	Investigative	76321186	C22H21ClN4O3	424.9	COC(=O)C1=CC(=NC=C1)C2=NC=CC(=C2)C(=O)NC3=CC=C(C=C3)[C@@H]4C[C@H]4N.Cl	IC50 = 76000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B4PDR6	2-[1-(1-Acetylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191477	C15H17N5O3	315.33	CC(=O)N1CCCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B5MF0W	2-[1-(2-Phenylethyl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191459	C16H14N4O2	294.31	C1=CC=C(C=C1)CCN2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 79432.82 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B5WC8Q	Potassium;2-(1-benzyltriazol-4-yl)pyridine-4-carboxylate	Investigative	122191457	C15H11KN4O2	318.37	C1=CC=C(C=C1)CN2C=C(N=N2)C3=NC=CC(=C3)C(=O)[O-].[K+]	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B6FWZ9	2-[1-[1-(3-Phenylpropanoyl)piperidin-4-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191466	C22H23N5O3	405.4	C1CN(CCC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)CCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B70ITZ	2-[1-(1-Ethoxycarbonylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191461	C16H19N5O4	345.35	CCOC(=O)N1CCC(CC1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B74FJW	2-[1-(1-Benzoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191470	C18H15N5O3	349.3	C1C(CN1C(=O)C2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 = 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B76BPD	3-[[4-[4-(3,4-Dichlorophenyl)piperazin-1-yl]-6-indazol-2-ylpyrimidin-2-yl]amino]propanoic acid	Investigative	127037169	C24H23Cl2N7O2	512.4	C1CN(CCN1C2=CC(=C(C=C2)Cl)Cl)C3=NC(=NC(=C3)N4C=C5C=CC=CC5=N4)NCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B7RPS8	2-[1-[1-(2-Phenylacetyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191475	C20H19N5O3	377.4	C1CN(CC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)CC4=CC=CC=C4	IC50 = 50118.72 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B87JUZ	2-Hydrazinylpyrimidine-4-carboxylic acid	Investigative	83672127	C5H6N4O2	154.13	C1=CN=C(N=C1C(=O)O)NN	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B8CYE9	3-Aminoisonicotinic acid	Investigative	459531	C6H6N2O2	138.12	C1=CN=CC(=C1C(=O)O)N	IC50 = 63095.73 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B8MFB0	2-[1-(1-Butanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191463	C17H21N5O3	343.4	CCCC(=O)N1CCC(CC1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B9PNO0	4-(Isopropylamino)-4-oxobutanoic acid	Investigative	245007	C7H13NO3	159.18	CC(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	B9WUE1	2-[(1-Benzyl-1h-Pyrazol-4-Yl)oxy]pyrido[3,4-D]pyrimidin-4(3h)-One	Investigative	135567128	C17H13N5O2	319.32	C1=CC=C(C=C1)CN2C=C(C=N2)OC3=NC4=C(C=CN=C4)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BA3E2S	2-[1-(Cyclohexylmethyl)-1H-pyrazole-4-yloxy]-3,4-dihydropyrido[3,4-d]pyrimidine-4-one	Investigative	136053677	C17H19N5O2	325.4	C1CCC(CC1)CN2C=C(C=N2)OC3=NC4=C(C=CN=C4)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BAT6I0	2-[1-(1-Propanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191468	C14H15N5O3	301.3	CCC(=O)N1CC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 50118.72 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BB3XA1	5-Chloro-7-[benzoylamino(3-methyl-2-thienyl)methyl]-8-quinolinol	Investigative	122383780	C22H17ClN2O2S	408.9	CC1=C(SC=C1)C(C2=CC(=C3C=CC=NC3=C2O)Cl)NC(=O)C4=CC=CC=C4	IC50 = 106000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BBE53M	Potassium;2-(1-ethyltriazol-4-yl)pyridine-4-carboxylate	Investigative	122191453	C10H9KN4O2	256.3	CCN1C=C(N=N1)C2=NC=CC(=C2)C(=O)[O-].[K+]	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BDI7W1	2-(1-Benzylpyrazol-4-yl)oxy-3H-pyrido[2,3-d]pyrimidin-4-one	Investigative	136644692	C17H13N5O2	319.32	C1=CC=C(C=C1)CN2C=C(C=N2)OC3=NC4=C(C=CC=N4)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BE5Y8W	4-Pyridinecarboxylic acid, 3-[(3-aminopropyl)amino]-	Investigative	83698744	C9H13N3O2	195.22	C1=CN=CC(=C1C(=O)O)NCCCN	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BF1XH6	2-[1-[1-(3-Phenylpropanoyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191472	C20H19N5O3	377.4	C1C(CN1C(=O)CCC2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BG3DF8	2-[(1-Cyclopentylpyrazol-4-yl)oxy]pyrido[3,4-d]pyrimidin-4-ol	Investigative	136053680	C15H15N5O2	297.31	C1CCC(C1)N2C=C(C=N2)OC3=NC4=C(C=CN=C4)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BIXF84	(3-Carboxypropanoylamino)-trimethylazanium	Investigative	71453382	C7H15N2O3+	175.21	C[N+](C)(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BKM38H	3-Benzamidopyridine-4-carboxylic acid	Investigative	64394359	C13H10N2O3	242.23	C1=CC=C(C=C1)C(=O)NC2=C(C=CN=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BL1D0W	2-[1-[(3R)-1-Benzoylpiperidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	101882871	C20H19N5O3	377.4	C1C[C@H](CN(C1)C(=O)C2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BLR79X	2-[1-(1-Propanoylpiperidin-4-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191462	C16H19N5O3	329.35	CCC(=O)N1CCC(CC1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 63095.73 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BN86AV	N'1,N'1,N'4,N'4-Tetramethylsuccinohydrazide	Investigative	2238068	C8H18N4O2	202.25	CN(C)NC(=O)CCC(=O)NN(C)C	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BOE1M8	2-[1-(1-Butanoylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191469	C15H17N5O3	315.33	CCCC(=O)N1CC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 63095.73 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BOQ2S3	2-[1-[1-(2-Phenylacetyl)azetidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191471	C19H17N5O3	363.4	C1C(CN1C(=O)CC2=CC=CC=C2)N3C=C(N=N3)C4=NC=CC(=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BP9YQ6	4-Hydrazinyl-4-oxobutanoic acid	Investigative	222878	C4H8N2O3	132.12	C(CC(=O)O)C(=O)NN	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BQ6XN3	2-[1-[1-(3-Phenylpropanoyl)pyrrolidin-3-yl]triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191476	C21H21N5O3	391.4	C1CN(CC1N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O)C(=O)CCC4=CC=CC=C4	IC50 = 79432.82 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BQW5X1	2-[1-(1-Butanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191479	C17H21N5O3	343.4	CCCC(=O)N1CCCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 79432.82 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BR6FJ9	2-(2h-1,2,3-Triazol-4-Yl)pyridine-4-Carboxylic Acid	Investigative	91801131	C8H6N4O2	190.16	C1=CN=C(C=C1C(=O)O)C2=NNN=C2	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BT0BE3	4-(2-Methylhydrazinyl)-4-oxobutanoic acid	Investigative	71458738	C5H10N2O3	146.14	CNNC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BT3E7X	2-[(3-Methylthiophen-2-yl)methylamino]pyridine-3-carboxylic acid	Investigative	112726150	C12H12N2O2S	248.3	CC1=C(SC=C1)CNC2=C(C=CC=N2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BT41XN	Tetrazole-5-acetohydrazide	Investigative	55281807	C3H6N6O	142.12	C(C1=NNN=N1)C(=O)NN	IC50 = 98000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BTC9Q4	2-[1-(1-Propanoylpiperidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191478	C16H19N5O3	329.35	CCC(=O)N1CCCC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 50118.72 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BV2PG8	Potassium;2-[1-(3-methylphenyl)triazol-4-yl]pyridine-4-carboxylate	Investigative	122191455	C15H11KN4O2	318.37	CC1=CC(=CC=C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)[O-].[K+]	IC50 = 50118.72 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BVE23M	4-[Dimethylamino(methyl)amino]-4-oxobutanoic acid	Investigative	71451542	C7H14N2O3	174.2	CN(C)N(C)C(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BVPH69	5-Quinolinecarboxylic acid, 8-hydroxy-, octyl ester	Investigative	125377518	C18H23NO3	301.4	CCCCCCCCOC(=O)C1=C2C=CC=NC2=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BW3UN6	Tranylcypromine hydrochloride	Investigative	2723716	C9H12ClN	169.65	C1[C@H]([C@@H]1N)C2=CC=CC=C2.Cl	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BWF9L0	Potassium;2-(1-methyltriazol-4-yl)pyridine-4-carboxylate	Investigative	122191451	C9H7KN4O2	242.28	CN1C=C(N=N1)C2=NC=CC(=C2)C(=O)[O-].[K+]	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BX63EH	2-[1-(2-Phenoxyethyl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191460	C16H14N4O3	310.31	C1=CC=C(C=C1)OCCN2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 = 79432.82 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BXH62K	4-Pyridinecarboxylic acid, 3-[(2-aminoethyl)amino]-	Investigative	71765999	C8H11N3O2	181.19	C1=CN=CC(=C1C(=O)O)NCCN	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BY36HT	2-[5-(2-Methoxyethanoylamino)-2-Oxidanyl-Phenyl]pyridine-4-Carboxylic Acid	Investigative	135567037	C15H14N2O5	302.28	COCC(=O)NC1=CC(=C(C=C1)O)C2=NC=CC(=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	BZ7O5X	2-[1-(1-Acetylazetidin-3-yl)triazol-4-yl]pyridine-4-carboxylic acid	Investigative	122191467	C13H13N5O3	287.27	CC(=O)N1CC(C1)N2C=C(N=N2)C3=NC=CC(=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T56057	Lysine-specific demethylase 6B	D0B2WZ	daminozide	Investigative	15331	C6H12N2O3	160.17	CN(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder