TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T57700	Tyrosine-protein kinase Kit	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	B1CT9I	(4S,6R,12E)-6-Chloro-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	Investigative	49842669	C19H23ClO5	366.8	C[C@H]1C[C@H](CC(=O)CCC/C=C/C2=C(C(=CC(=C2)OC)O)C(=O)O1)Cl	IC50 ~ 100000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	B3X2WM	1-(3-Methylphenyl)-3-[4-[3-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridin-4-yl]phenyl]urea	Investigative	137657952	C21H16F3N5O	411.4	CC1=CC(=CC=C1)NC(=O)NC2=CC=C(C=C2)C3=CC=NC4=NNC(=C34)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	B5JX9Z	Chembl4246600	Investigative	141523058	C23H28N6O4	452.5	C1CCC(CC1)NC2=NC(=NC3=C2COC3)N4CCC(C4)NC(=O)C5=NC=C(C=C5)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	B5YNV2	6,6-Dimethyl-8-(1-(oxetan-3-yl)piperidin-4-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile	Investigative	53357328	C27H27N3O2	425.5	CC1(C2=C(C=CC(=C2)C3CCN(CC3)C4COC4)C(=O)C5=C1NC6=C5C=CC(=C6)C#N)C	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	B60CAW	(R)-3-(6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylamide	Investigative	46232555	C20H15Cl2FN2O2	405.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)/C=C/C(=O)N	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	B9G5NX	Chembl4250883	Investigative	141523067	C23H30N6O4	454.5	CCCCCCNC1=NC(=NC2=C1COC2)N3CCC(C3)NC(=O)C4=NC=C(C=C4)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BBY4K7	1-(3-Thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazole-5-carbonyl)-piperidine-4-carboxylic acid	Investigative	44440231	C21H19N3O3S	393.5	C1CN(CCC1C(=O)O)C(=O)C2=CC=CC3=C2CC4=C3NN=C4C5=CSC=C5	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BCI78A	Chembl4245985	Investigative	141523061	C24H24N6O4	460.5	CC1=CC=C(C=C1)NC2=NC(=NC3=C2COC3)N4CCC(C4)NC(=O)C5=NC=C(C=C5)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BFK14D	1-Cyclohexyl-3-[4-(3-methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]urea	Investigative	137654848	C20H23N5O	349.4	CC1=C2C(=CC=NC2=NN1)C3=CC=C(C=C3)NC(=O)NC4CCCCC4	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BG7LP5	1-(3-Thiophen-3-yl-2,4-dihydro-indeno[1,2-c]pyrazole-5-carbonyl)-piperidine-3-carboxylic acid	Investigative	44440232	C21H19N3O3S	393.5	C1CC(CN(C1)C(=O)C2=CC=CC3=C2CC4=C3NN=C4C5=CSC=C5)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BJ1HE9	(4S,6R,12Z)-6-Chloro-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	Investigative	53324892	C19H23ClO5	366.8	C[C@H]1C[C@H](CC(=O)CCC/C=C\\C2=C(C(=CC(=C2)OC)O)C(=O)O1)Cl	IC50 = 100000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BKSR53	(4S,6R,12Z)-6-Bromo-18-hydroxy-16-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),12,15,17-tetraene-2,8-dione	Investigative	53320915	C19H23BrO5	411.3	C[C@H]1C[C@H](CC(=O)CCC/C=C\\C2=C(C(=CC(=C2)OC)O)C(=O)O1)Br	IC50 = 81000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BM0PQ7	Chembl4247042	Investigative	141523085	C22H28N6O4	440.5	CCCCCNC1=NC(=NC2=C1COC2)N3CCC(C3)NC(=O)C4=NC=C(C=C4)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BNH6Q2	1-(2,2-Diethoxyethyl)-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrazolo[3,4-d]pyrimidin-4-amine	Investigative	122705261	C18H21N7O2	367.4	CCOC(CN1C2=NC=NC(=C2C(=N1)C3=CN=C4C(=C3)C=CN4)N)OCC	IC50 ~ 100000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BO2IH0	Chembl4248043	Investigative	141523076	C25H26N6O4	474.5	CCC1=CC=C(C=C1)NC2=NC(=NC3=C2COC3)N4CCC(C4)NC(=O)C5=NC=C(C=C5)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BO5CI8	3-(2-Chlorophenyl)-1-methyl-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)urea	Investigative	44414371	C29H31ClN6OS	547.1	CN1CCN(CC1)CC2=CC3=C(C=C2)C4=NNC(=C4C3)C5=CC=C(S5)CN(C)C(=O)NC6=CC=CC=C6Cl	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BO71ZH	Chembl4243462	Investigative	145984021	C25H26N6O6	506.5	COC1=C(C=C(C=C1)NC2=NC(=NC3=C2COC3)N4CCC(C4)NC(=O)C5=NC=C(C=C5)C(=O)O)OC	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BP34EV	Chembl4239846	Investigative	141523059	C21H26N6O5	442.5	COCCCNC1=NC(=NC2=C1COC2)N3CCC(C3)NC(=O)C4=NC=C(C=C4)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BQ1W5F	5-[4-Amino-1-(2,2-dimethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine	Investigative	127045861	C16H17N7O3	355.35	COC(CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N)OC	IC50 ~ 100000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BQO39K	4-(6,7-Dimethoxyquinazolin-4-yl)-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]piperazine-1-carbothioamide	Investigative	59020517	C25H26N8O4S2	566.7	COC1=C(C=C2C(=C1)C(=NC=N2)N3CCN(CC3)C(=S)NC4=CC=C(C=C4)S(=O)(=O)NC5=NC=CC=N5)OC	IC50 = 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BT0V7B	5-[4-Amino-1-(1,3-dioxolan-2-ylmethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine	Investigative	127046862	C16H15N7O3	353.34	C1COC(O1)CN2C3=NC=NC(=C3C(=N2)C4=CC5=C(C=C4)OC(=N5)N)N	IC50 ~ 100000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BTR7F5	Chembl4243810	Investigative	141523091	C25H26N6O4	474.5	CC1=C(C=C(C=C1)NC2=NC(=NC3=C2COC3)N4CCC(C4)NC(=O)C5=NC=C(C=C5)C(=O)O)C	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BUBK49	(1S)-2-(1H-Indol-3-YL)-1-[({5-[(E)-2-pyridin-4-ylvinyl]pyridin-3-YL}oxy)methyl]ethylamine	Investigative	6914613	C23H22N4O	370.4	C1=CC=C2C(=C1)C(=CN2)C[C@@H](COC3=CN=CC(=C3)/C=C/C4=CC=NC=C4)N	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BVG3F6	4-Pyrido[2,3]thieno[2,4-d]pyrimidin-4-yl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]piperazine-1-carbothioamide	Investigative	59020502	C24H21N9O2S3	563.7	C1CN(CCN1C2=NC=NC3=C2SC4=C3C=CC=N4)C(=S)NC5=CC=C(C=C5)S(=O)(=O)NC6=NC=CC=N6	IC50 = 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BW14ZG	Chembl4250240	Investigative	145983151	C24H24N6O5	476.5	COC1=CC=C(C=C1)NC2=NC(=NC3=C2COC3)N4CCC(C4)NC(=O)C5=NC=C(C=C5)C(=O)O	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BXB01F	5-[4-Amino-1-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine	Investigative	122163152	C18H21N7O3	383.4	CCOC(CN1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N)OCC	IC50 ~ 100000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BY4R9U	1-(2-Methoxyethyl)-1-((5-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)thiophen-2-yl)methyl)-3-m-tolylurea	Investigative	44414395	C32H38N6O2S	570.7	CC1=CC(=CC=C1)NC(=O)N(CCOC)CC2=CC=C(S2)C3=C4CC5=C(C4=NN3)C=CC(=C5)CN6CCN(CC6)C	IC50 ~ 50000 nM	Poor binder
T57700	Tyrosine-protein kinase Kit	BYL30S	Chembl4244068	Investigative	141523068	C22H28N6O5	456.5	CCOCCCNC1=NC(=NC2=C1COC2)N3CCC(C3)NC(=O)C4=NC=C(C=C4)C(=O)O	IC50 ~ 50000 nM	Poor binder