TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T65864	Stress-activated protein kinase 2a	D02WCI	Pirfenidone	Approved	40632	C12H11NO	185.22	CC1=CN(C(=O)C=C1)C2=CC=CC=C2	IC50 = 165400 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D0AZ3C	Imatinib	Approved	5291	C29H31N7O	493.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D08DNZ	PMID25991433-Compound-P6	Patented	45102739	C17H12ClN5OS	369.8	C1=CC2=C(C=CN=C2)C(=C1)CC(=O)NC3=C(C(=CS3)Cl)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D0W8BL	PMID25991433-Compound-P5	Patented	46868926	C18H11BrF3N5O2S	498.3	C1=CC2=C(C=CC(=O)N2CC(=O)NC3=C(C(=CS3)Br)C4=NC=NN4)C=C1C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B08AYZ	3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione	Investigative	44575127	C21H17N3O2S	375.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CSC=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B0ESC4	CID 25181471	Investigative	25181471	C25H24N4O2	412.5	CC1=C(C=C(C=C1)C2=NC=C(N2C)C)NC(=O)C3=CC=C(C=C3)OCC4=CC=CC=N4	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B0IQZ8	4-Benzoyl-1-(3-nitrophenyl)-1H-pyrazol-5-amine	Investigative	11529647	C16H12N4O3	308.29	C1=CC=C(C=C1)C(=O)C2=C(N(N=C2)C3=CC(=CC=C3)[N+](=O)[O-])N	IC50 ~ 56000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B0REW7	4-(Naphthalen-2-yl)-3-(2-(thiazol-2-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53317414	C20H14N6OS	386.4	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=O)C4=CC(=NC=C4)NC5=NC=CS5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B0V4FL	[(2R,3S,4R,5R,6R)-3,4,6-Triacetyloxy-5-[4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-oxazol-2-yl]triazol-1-yl]oxan-2-yl]methyl acetate	Investigative	76325327	C30H28FN5O10	637.6	CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OC(=O)C)N2C=C(N=N2)C3=NC(=C(O3)C4=CC=NC=C4)C5=CC=C(C=C5)F)OC(=O)C)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B1IU9S	N-[2-Methyl-5-[5-(trifluoromethyl)-1H-pyrazol-3-yl]phenyl]-4-(pyridin-2-ylmethoxy)benzamide	Investigative	70696850	C24H19F3N4O2	452.4	CC1=C(C=C(C=C1)C2=NNC(=C2)C(F)(F)F)NC(=O)C3=CC=C(C=C3)OCC4=CC=CC=N4	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B1JRW4	ClC=1C=C(C=C(C1O)Cl)C1=CN=C2C(=N1)N=C(C=C2)NC(=O)NCC	Investigative	136125942	C16H13Cl2N5O2	378.2	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=C(C(=C3)Cl)O)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B1M9BY	1-Ethyl-3-[3-(3-propan-2-yloxyanilino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881818	C19H22N6O2	366.4	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=CC=C3)OC(C)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B1PW7U	N-[4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(6,7-difluoro-2-oxoquinolin-1-yl)acetamide	Investigative	46868925	C17H10BrF2N5O2S	466.3	C1=CC(=O)N(C2=CC(=C(C=C21)F)F)CC(=O)NC3=C(C(=CS3)Br)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B1R3DV	4-(Naphthalen-2-yl)-3-(2-(pyridin-3-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53321577	C22H16N6O	380.4	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=O)C4=CC(=NC=C4)NC5=CN=CC=C5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B1RS9X	4-(Naphthalen-2-yl)-3-(pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53317412	C17H12N4O	288.3	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=O)C4=CC=NC=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B20NZH	2-(1-Benzyltriazol-4-yl)-4-(4-fluorophenyl)-5-pyridin-4-yl-1,3-oxazole	Investigative	76332536	C23H16FN5O	397.4	C1=CC=C(C=C1)CN2C=C(N=N2)C3=NC(=C(O3)C4=CC=NC=C4)C5=CC=C(C=C5)F	IC50 = 158000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B26WSU	N-(4,4''-Bithiazol-5-yl)-2-(isoquinolin-5-yl)acetamide	Investigative	49839481	C17H12N4OS2	352.4	C1=CC2=C(C=CN=C2)C(=C1)CC(=O)NC3=C(N=CS3)C4=CSC=N4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B2Q3ND	1-Ethyl-3-[3-(3-hydroxy-phenyl)-pyrido[2,3-b]pyrazine-6-yl]-urea	Investigative	58881893	C16H15N5O2	309.32	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B2QXF4	4-Methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3-yl]-N-(5-methyl-1,3-thiazol-2-yl)benzamide	Investigative	70694241	C25H26N6O2S	474.6	CC1=C(C=C(C=C1)C(=O)NC2=NC=C(S2)C)N3C=NC4=C(C3=O)C=C(C=C4)N5CCN(CC5)C	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B2T0RU	CID 46179972	Investigative	46179972	C28H31N6O3	499.6	CC1(CC(CC(N1[O])(C)C)NC(=O)C2=CC=CC(=C2)C3=NN4C(=CC=NC4=C3)NC5=CC(=CC=C5)O)C	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B36RWG	4-[(4-Methylpiperazin-1-yl)methyl]-N-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]benzamide	Investigative	49863687	C29H36N4O3	488.6	CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C4=CC=CC=C43)OCCN5CCOCC5	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B39IGT	4-(6-Bromonaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53323987	C22H20BrN5O2	466.3	C1COCCC1NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=C(C=C4)C=C(C=C5)Br	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B3FO6S	1-Ethyl-3-[3-[(6-methoxypyridin-3-yl)amino]pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881868	C16H17N7O2	339.35	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CN=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B3M6DB	N-[4-Cyano-3-(1h-1,2,4-Triazol-5-Yl)thiophen-2-Yl]-2-(2-Oxo-3,4-Dihydroquinolin-1(2h)-Yl)acetamide	Investigative	46869880	C18H14N6O2S	378.4	C1CC(=O)N(C2=CC=CC=C21)CC(=O)NC3=C(C(=CS3)C#N)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B3T9QN	Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44219749	C24H29N7O5	495.5	COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B3UI9B	1-(2-Hydroxy-2-methylpropyl)-N-(5-((7-methoxyquinolin-4-yl)oxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide	Investigative	24764449	C30H29N5O5	539.6	CC1=C(C(=O)N(N1CC(C)(C)O)C2=CC=CC=C2)C(=O)NC3=NC=C(C=C3)OC4=C5C=CC(=CC5=NC=C4)OC	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B3X1LZ	N-(2-Methoxyethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232269	C8H9N5O3S3	319.4	COCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B45PTN	1-Ethyl-3-[3-(pyrazin-2-ylamino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881915	C14H14N8O	310.31	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=NC=CN=C3	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B49BPE	Triazole, 7b	Investigative	42618077	C16H10Cl2N6O2S2	453.3	CN1C=CC=C1C2=NN=C(N2C3=C(C=C(C=C3)Cl)Cl)SC4=NC=C(S4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B4F8MO	Schembl22388257	Investigative	56682210	C18H11BrN6O2S	455.3	C1=CC2=C(C=CC(=O)N2CC(=O)NC3=C(C(=CS3)Br)C4=NC=NN4)C=C1C#N	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B4I1HL	4',3''-Di-O-methylapocynin-B	Investigative	50908213	C26H24O10	496.5	COC1=C(C=CC(=C1)[C@H]2CC(=O)OC3=C2C4=C(C[C@@H]([C@H](O4)C5=CC(=C(C(=C5)O)OC)O)O)C(=C3)O)O	IC50 = 50800 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B4P9TV	N-(3,4-Dimethoxyphenethyl)-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232270	C15H15N5O4S3	425.5	COC1=C(C=C(C=C1)CCNC2=NN=C(S2)SC3=NC=C(S3)[N+](=O)[O-])OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B4REL1	2-(Isoquinolin-5-yl)-n-(4-(1-methyl-1h-1,2,4-triazol-5-yl)thiazol-5-yl)acetamide	Investigative	52942507	C17H14N6OS	350.4	CN1C(=NC=N1)C2=C(SC=N2)NC(=O)CC3=CC=CC4=C3C=CN=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B4T2QU	N-Methyl-4-(4-(4-((4-methylpiperazin-1-yl)methyl)benzamido)phenoxy)picolinamide	Investigative	49863686	C26H29N5O3	459.5	CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)CN4CCN(CC4)C	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B4VE0K	1-[3-(4-Chloroanilino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881789	C16H15ClN6O	342.78	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5ADH9	1-Ethyl-3-[3-(4-fluoroanilino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881805	C16H15FN6O	326.33	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5GQZ0	N-(4-(1H-1,2,4-Triazol-3-yl)thiazol-5-yl)-2-(isoquinolin-5-yl)acetamide	Investigative	46869149	C16H12N6OS	336.4	C1=CC2=C(C=CN=C2)C(=C1)CC(=O)NC3=C(N=CS3)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5JPZ8	5-N-(4-Aminocyclohexyl)-7-N-(3-chloro-4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine	Investigative	9907612	C18H20ClFN6	374.8	C1CC(CCC1N)NC2=NC3=CC=NN3C(=C2)NC4=CC(=C(C=C4)F)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5K6SR	3-(2-Aminoanilino)-8-methoxy-6H-benzo[c][1]benzoxepin-11-one	Investigative	72713770	C21H18N2O3	346.4	COC1=CC2=C(C=C1)C(=O)C3=C(C=C(C=C3)NC4=CC=CC=C4N)OC2	IC50 = 71790 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5NSE7	4-(4-Methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile	Investigative	45375865	C28H28N6O2S	512.6	CC1=C(C=CC2=C1C=CN2)NC3=C(C=NC=C3/C=C/C4=CC(=CC=C4)S(=O)(=O)N5CCN(CC5)C)C#N	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5OL9T	[4-[6-(Ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]-2-methoxyphenyl] 4-methylbenzenesulfonate	Investigative	91799561	C24H23N5O5S	493.5	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=C(C=C3)OS(=O)(=O)C4=CC=C(C=C4)C)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5PU4C	1-(3-Hydroxypropyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea	Investigative	58881946	C17H17N5O2	323.35	C1=CC=C(C=C1)C2=CN=C3C=CC(=NC3=N2)NC(=O)NCCCO	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5V2EO	N-(5-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-4-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)acetamide	Investigative	25195322	C17H15N7O	333.3	CC1=NC(=CC=C1)C2=C(N=C(N2)NC(=O)C)C3=CN4C(=NC=N4)C=C3	EC50 = 57800 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B5Z3KC	4-(8-Aminonaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53325285	C22H22N6O2	402.4	C1COCCC1NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=C(C=CC=C5N)C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B60UFA	4-(2-Cyanophenoxy)-N-(pyrimidin-4-ylmethyl)benzamide	Investigative	118725453	C19H14N4O2	330.3	C1=CC=C(C(=C1)C#N)OC2=CC=C(C=C2)C(=O)NCC3=NC=NC=C3	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B6G8HM	2-(Isoquinolin-5-yl)-n-(4-(pyrazin-2-yl)thiazol-5-yl)acetamide	Investigative	52948593	C18H13N5OS	347.4	C1=CC2=C(C=CN=C2)C(=C1)CC(=O)NC3=C(N=CS3)C4=NC=CN=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B6KL3D	N-[2-Methyl-5-(5-methyl-1H-imidazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide	Investigative	70690618	C24H22N4O2	398.5	CC1=C(C=C(C=C1)C2=C(NC=N2)C)NC(=O)C3=CC=C(C=C3)OCC4=CC=CC=N4	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B73JLM	N-[4-Cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-quinolin-5-ylacetamide	Investigative	46868856	C18H12N6OS	360.4	C1=CC(=C2C=CC=NC2=C1)CC(=O)NC3=C(C(=CS3)C#N)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7F6VX	Methyl 4-(2-(naphthalen-1-yl)acetamido)-1H-pyrazole-3-carboxylate	Investigative	52941226	C17H15N3O3	309.32	COC(=O)C1=C(C=NN1)NC(=O)CC2=CC=CC3=CC=CC=C32	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7G8HC	1-Ethyl-3-[3-[(5-methylpyridin-2-yl)amino]pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881853	C16H17N7O	323.35	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=NC=C(C=C3)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7GVJ1	5-(5-Nitrothiazol-2-ylthio)-N-propyl-1,3,4-thiadiazol-2-amine	Investigative	46232267	C8H9N5O2S3	303.4	CCCNC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7I3DW	N-(2-(5-Amino-1H-1,2,4-triazol-3-yl)thiophen-3-yl)-2-(4-methoxyphenyl)acetamide	Investigative	46869742	C15H15N5O2S	329.4	COC1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)C3=NC(=NN3)N	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7MO4E	4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide	Investigative	24959046	C21H26N6O	378.5	CN(C)CCNC(=O)C1=CC=C(C=C1)C2=CN=C3N2N=C(C=C3)NCC4CC4	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7OTS6	1-Ethyl-3-[3-[(1-methylpyrazol-3-yl)amino]pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881938	C14H16N8O	312.33	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=NN(C=C3)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7TOP2	N-[3-[[7-(2-Morpholin-4-ylethoxy)-11-oxo-6H-benzo[c][1]benzoxepin-3-yl]amino]phenyl]furan-3-carboxamide	Investigative	72714224	C31H29N3O6	539.6	C1COCCN1CCOC2=CC=CC3=C2COC4=C(C3=O)C=CC(=C4)NC5=CC(=CC=C5)NC(=O)C6=COC=C6	IC50 = 51380 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B7Y1AT	(3Z,5Z)-3,5-Bis(pyridin-2-ylmethylidene)thian-4-one	Investigative	56832546	C17H14N2OS	294.4	C\\1SC/C(=C\\C2=CC=CC=N2)/C(=O)/C1=C/C3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B81JYI	Disodium;2-[4-[2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyrimidin-7-yl]triazol-1-yl]ethyl-dioxido-oxo-lambda5-phosphane	Investigative	118707526	C21H16FN8Na2O3PS	556.4	CSC1=NC=CC(=N1)C2=C(N=C3N2C=CC(=N3)C4=CN(N=N4)CCP(=O)([O-])[O-])C5=CC=C(C=C5)F.[Na+].[Na+]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B81SEG	[(2R,3S,4R,5R,6R)-3,4,6-Triacetyloxy-5-[4-[4-(4-fluorophenyl)-1-methyl-5-pyridin-4-ylimidazol-2-yl]triazol-1-yl]oxan-2-yl]methyl acetate	Investigative	76328868	C31H31FN6O9	650.6	CC(=O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OC(=O)C)N2C=C(N=N2)C3=NC(=C(N3C)C4=CC=NC=C4)C5=CC=C(C=C5)F)OC(=O)C)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B82ZNP	4-(8-Fluoronaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53318709	C22H20FN5O2	405.4	C1COCCC1NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=C(C=CC=C5F)C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8IA0R	3-(2-(Cyclohexylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1-(pyridin-4-ylmethyl)-1H-1,2,4-triazol-5(4H)-one	Investigative	50941539	C29H28N6O	476.6	C1CCC(CC1)NC2=NC=CC(=C2)C3=NN(C(=O)N3C4=CC5=CC=CC=C5C=C4)CC6=CC=NC=C6	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8ISP5	N-(4-Cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(isoquinolin-5-yl)acetamide	Investigative	46868853	C18H12N6OS	360.4	C1=CC2=C(C=CN=C2)C(=C1)CC(=O)NC3=C(C(=CS3)C#N)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8JNY5	3-(2-(Cyclohexylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	50941455	C23H23N5O	385.5	C1CCC(CC1)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8OGN1	Unii-O5YT36mst0	Investigative	9885748	C19H15F2NO	311.3	C\\1NC/C(=C\\C2=CC=CC=C2F)/C(=O)/C1=C/C3=CC=CC=C3F	IC50 = 92000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8R2JO	1-Ethyl-3-[3-(4-hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	135771987	C16H15N5O2	309.32	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8RO2V	ClC1=C(CNC2=NC(=NN2)C2=CC(=C(C=C2)OC)OC)C(=CC=C1)F	Investigative	130429244	C17H16ClFN4O2	362.8	COC1=C(C=C(C=C1)C2=NC(=NN2)NCC3=C(C=CC=C3Cl)F)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8WEI0	4-(Naphthalen-2-yl)-1-(piperidin-4-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53326558	C27H30N6O2	470.6	C1CNCCC1N2C(=O)N(C(=N2)C3=CC(=NC=C3)NC4CCOCC4)C5=CC6=CC=CC=C6C=C5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8XG9W	3-{[(1R)-1-Phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione	Investigative	15295578	C17H15N3O2	293.32	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B8Y2SJ	3-(2,4-Difluoroanilino)-8-(2-morpholin-4-ylethoxy)-6H-benzo[c][1]benzoxepin-11-one	Investigative	72713978	C26H24F2N2O4	466.5	C1COCCN1CCOC2=CC3=C(C=C2)C(=O)C4=C(C=C(C=C4)NC5=C(C=C(C=C5)F)F)OC3	IC50 = 71790 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B9SNL5	CCNC(=O)Nc1ccc2ncc(Nc3cc(Cl)c(O)c(Cl)c3)nc2n1	Investigative	136125939	C16H14Cl2N6O2	393.2	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=C(C(=C3)Cl)O)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	B9ZS7X	N-[4-(4-Naphthalen-2-yl-5-oxo-1H-1,2,4-triazol-3-yl)pyridin-2-yl]acetamide	Investigative	53321333	C19H15N5O2	345.4	CC(=O)NC1=NC=CC(=C1)C2=NNC(=O)N2C3=CC4=CC=CC=C4C=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BA14BC	N-Methyl-4-(4-(3-(4-((4-methylpiperazin-1-yl)methyl)phenyl)ureido)phenoxy)picolinamide	Investigative	49863710	C26H30N6O3	474.6	CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)CN4CCN(CC4)C	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BA1S4N	N-[4-Methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3-yl]phenyl]-1,3-thiazole-2-carboxamide	Investigative	70681603	C24H24N6O2S	460.6	CC1=C(C=C(C=C1)NC(=O)C2=NC=CS2)N3C=NC4=C(C3=O)C=C(C=C4)N5CCN(CC5)C	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BA2KV3	1-[3-(4-Hydroxyphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-prop-2-enylurea	Investigative	135461970	C17H15N5O2	321.33	C=CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BA62QX	4-(4-Methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	24766030	C24H21N5OS	427.5	CC1=C(C=CC2=C1C=CN2)NC3=C4C=C(SC4=NC=C3C#N)/C=C/C(=O)N5CCCC5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BATG37	7-Methoxy-3,4,5,10-tetrahydro-1H-2,5-methanoazepino[3,4-b]indole-1-carboxylic Acid	Investigative	23661564	C15H16N2O3	272.3	COC1=CC2=C(C=C1)NC3=C2C4CCN(C4)C3C(=O)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BB2FC8	3-(2,4-Difluoroanilino)-7-[(2S)-2,3-dihydroxypropoxy]-6H-benzo[c][1]benzoxepin-11-one	Investigative	72713766	C23H19F2NO5	427.4	C1C2=C(C=CC=C2OC[C@H](CO)O)C(=O)C3=C(O1)C=C(C=C3)NC4=C(C=C(C=C4)F)F	IC50 = 90410 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BB2Z0H	1-[3-[(2-Chloropyridin-4-yl)amino]pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881831	C15H14ClN7O	343.77	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=NC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BB4QP8	3-(2-(Cyclohexylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53323989	C29H33N5O2	483.6	C1CCC(CC1)NC2=NC=CC(=C2)C3=NN(C(=O)N3C4=CC5=CC=CC=C5C=C4)CC6CCOCC6	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BB5X4R	4-Benzoyl-5-methyl-2-phenyl-1H-pyrazol-3(2H)-one	Investigative	354929	C17H14N2O2	278.3	CC1=C(C(=O)N(N1)C2=CC=CC=C2)C(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BB6A9P	4-Benzoyl-1-phenyl-1H-pyrazole-5-carbonitrile	Investigative	11630444	C17H11N3O	273.29	C1=CC=C(C=C1)C(=O)C2=C(N(N=C2)C3=CC=CC=C3)C#N	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BB7T4M	4-[2-(4-Ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-methylsulfanylpyrimidine	Investigative	118707543	C22H15FN4S	386.4	CSC1=NC=CC(=N1)C2=C(N=C(N2)C3=CC=C(C=C3)C#C)C4=CC=C(C=C4)F	IC50 = 82100 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BBA31U	N-[4-(4-Naphthalen-2-yl-5-oxo-1H-1,2,4-triazol-3-yl)pyridin-2-yl]benzamide	Investigative	53317415	C24H17N5O2	407.4	C1=CC=C(C=C1)C(=O)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BBED32	4-(6-Aminonaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53326557	C22H22N6O2	402.4	C1COCCC1NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=C(C=C4)C=C(C=C5)N	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BBJ2Y4	NC=1C=C(C=CC=1OC)C1=NNC(=N1)NCC1=C(C=CC=C1F)Cl	Investigative	130429224	C16H15ClFN5O	347.77	COC1=C(C=C(C=C1)C2=NC(=NN2)NCC3=C(C=CC=C3Cl)F)N	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BBWU23	n-(4-Bromo-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(isoquinolin-5-yl)acetamide	Investigative	46869878	C17H12BrN5OS	414.3	C1=CC2=C(C=CN=C2)C(=C1)CC(=O)NC3=C(C(=CS3)Br)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BCR5D1	7-Methoxy-2-(2,3,4-trifluorophenylamino)-10,11-dihydrodibenzo[a,d]-cyclo-hepten-5-one	Investigative	60166861	C22H16F3NO2	383.4	COC1=CC2=C(CCC3=C(C2=O)C=CC(=C3)NC4=C(C(=C(C=C4)F)F)F)C=C1	IC50 = 81000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BCS51V	Methyl 4-(4-(naphthalen-2-yl)-5-oxo-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-4,5-dihydro-1H-1,2,4-triazol-1-yl)piperidine-1-carboxylate	Investigative	53325288	C29H32N6O4	528.6	COC(=O)N1CCC(CC1)N2C(=O)N(C(=N2)C3=CC(=NC=C3)NC4CCOCC4)C5=CC6=CC=CC=C6C=C5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BD6A0U	4-(Naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53323985	C22H21N5O2	387.4	C1COCCC1NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BDAC65	3-(2,4-Difluoroanilino)-8-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy]-6H-benzo[c][1]benzoxepin-11-one	Investigative	76328020	C26H23F2NO5	467.5	CC1(OC[C@H](O1)COC2=CC3=C(C=C2)C(=O)C4=C(C=C(C=C4)NC5=C(C=C(C=C5)F)F)OC3)C	IC50 = 91190 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BEW6F7	2-[2-(2-Fluorophenyl)pyridin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one	Investigative	11992146	C18H14FN3O	307.3	C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC=CC=C4F	IC50 = 87000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BF0G5W	(S)-2-(2,4-Difluorophenylamino)-8-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one	Investigative	45280584	C27H25F2NO4	465.5	CC1(OC[C@@H](O1)COC2=CC3=C(C=C2)C(=O)C4=C(CC3)C=C(C=C4)NC5=C(C=C(C=C5)F)F)C	IC50 = 170000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BF0W8I	N-Sec-Butyl-5-(5-nitrothiazol-2-ylthio)-1,3,4-thiadiazol-2-amine	Investigative	46232312	C9H11N5O2S3	317.4	CCC(C)NC1=NN=C(S1)SC2=NC=C(S2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BF32QN	1-(4-Hydroxybutyl)-3-(3-phenylpyrido[2,3-b]pyrazin-6-yl)urea	Investigative	58881771	C18H19N5O2	337.4	C1=CC=C(C=C1)C2=CN=C3C=CC(=NC3=N2)NC(=O)NCCCCO	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BG62DZ	1-Ethyl-3-[3-(1-methylpyrazol-4-yl)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881811	C14H15N7O	297.32	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CN(N=C3)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BGS51N	6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-1-carboxylic acid	Investigative	3848929	C13H14N2O3	246.26	COC1=CC2=C(C=C1)NC3=C2CCNC3C(=O)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BGSD18	3-[6-(Ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzoic acid	Investigative	58881861	C17H15N5O3	337.33	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BGUL90	6-(2,4-Difluoroanilino)-13-[[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]methoxy]tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-one	Investigative	60167140	C27H25F2NO4	465.5	CC1(OC[C@H](O1)COC2=CC3=C(C=C2)C(=O)C4=C(CC3)C=C(C=C4)NC5=C(C=C(C=C5)F)F)C	IC50 = 123000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BGYK42	Triazole, 3j	Investigative	25196726	C11H6N6O5S2	366.3	C1=CC(=CC=C1N2C(=O)NN=C2SC3=NC=C(S3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BH3E9B	n-(4-Methyl-3-(3-methyl-1h-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(quinolin-5-yl)acetamide	Investigative	46869817	C19H17N5OS	363.4	CC1=CSC(=C1C2=NNC(=N2)C)NC(=O)CC3=C4C=CC=NC4=CC=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BH6Q0Z	Thiourea, N-(3-(4-hydroxyphenyl)pyrido(2,3-b)pyrazin-6-yl)-N'-2-propenyl-	Investigative	135418481	C17H15N5OS	337.4	C=CCNC(=S)NC1=NC2=NC(=CN=C2C=C1)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BI0ZR6	(R)-8-(2-Aminophenylamino)-1-(2,3-dihydroxypropoxy)-10,11-dihydrodibenzo[a,d]cyclo-hepten-5-one	Investigative	45280693	C24H24N2O4	404.5	C1CC2=C(C=CC=C2OC[C@@H](CO)O)C(=O)C3=C1C=C(C=C3)NC4=CC=CC=C4N	IC50 = 78800 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BI1E4B	2-(4-Methoxyphenyl)-N-(2-(5-(trifluoromethyl)-1H-1,2,4-triazol-3-yl)thiophen-3-yl)acetamide	Investigative	46869740	C16H13F3N4O2S	382.4	COC1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)C3=NNC(=N3)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BIQ8U2	1-Benzyl-4-(benzyloxy)-3-vinylpyridin-2(1H)-one	Investigative	22051118	C21H19NO2	317.4	C=CC1=C(C=CN(C1=O)CC2=CC=CC=C2)OCC3=CC=CC=C3	IC50 = 72000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BIS86K	N-(4-Methyl-3-(3-methyl-1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide	Investigative	46869674	C19H19N5O2S	381.5	CC1=CSC(=C1C2=NNC(=N2)C)NC(=O)CN3C(=O)CCC4=CC=CC=C43	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BJ5A3U	[4-[6-(Ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]-2-methoxyphenyl] dihydrogen phosphate	Investigative	57947021	C17H18N5O6P	419.3	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=C(C=C3)OP(=O)(O)O)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BJE4N7	1-Ethyl-3-[3-(4-methoxyanilino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881819	C17H18N6O2	338.4	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC=C(C=C3)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BJI6C7	1-Ethyl-3-[3-(3-hydroxy-4-methylanilino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881874	C17H18N6O2	338.4	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=C(C=C3)C)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BJR3W2	1-[3-(4-Chloro-2-methoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881816	C17H16ClN5O2	357.8	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=C(C=C(C=C3)Cl)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BK07WJ	N-[4-(4-Naphthalen-2-yl-5-oxo-1H-1,2,4-triazol-3-yl)pyridin-2-yl]cyclopropanecarboxamide	Investigative	53321334	C21H17N5O2	371.4	C1CC1C(=O)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BK1V8Q	3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione	Investigative	44575126	C21H17N3O3	359.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CC=CO4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BK21VN	Halicin	Investigative	11837140	C5H3N5O2S3	261.3	C1=C(SC(=N1)SC2=NN=C(S2)N)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BK8FP3	ClC=1C=C(C=C(C1O)OC)C1=CN=C2C(=N1)N=C(C=C2)NC(=O)NCC	Investigative	136125927	C17H16ClN5O3	373.8	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=C(C(=C3)Cl)O)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BK96BW	3-[[6-(Ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]amino]-5-(trifluoromethyl)benzoic acid	Investigative	58881877	C18H15F3N6O3	420.3	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=CC(=C3)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BKBX35	1-Ethyl-3-[3-(pyridin-3-ylamino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881916	C15H15N7O	309.33	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BKG16O	4-[2-[1-(2-Diethoxyphosphorylethyl)triazol-4-yl]-5-(4-fluorophenyl)-3-methylimidazol-4-yl]pyridine	Investigative	76310785	C23H26FN6O3P	484.5	CCOP(=O)(CCN1C=C(N=N1)C2=NC(=C(N2C)C3=CC=NC=C3)C4=CC=C(C=C4)F)OCC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BKJ21G	ClC1=C(CNC2=NC(=NN2)C2=CC(=CC=C2)NC)C(=CC=C1)F	Investigative	130429255	C16H15ClFN5	331.77	CNC1=CC=CC(=C1)C2=NC(=NN2)NCC3=C(C=CC=C3Cl)F	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BKV41D	1-[3-(4-Cyanoanilino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881774	C17H15N7O	333.3	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC=C(C=C3)C#N	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BL3FE9	1-Ethyl-3-[3-(4-ethylanilino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881857	C18H20N6O	336.4	CCC1=CC=C(C=C1)NC2=CN=C3C=CC(=NC3=N2)NC(=O)NCC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BL73VY	N-[2-Methyl-5-(1,3,5-trimethylpyrazol-4-yl)phenyl]-4-(pyridin-2-ylmethoxy)benzamide	Investigative	70692760	C26H26N4O2	426.5	CC1=C(C=C(C=C1)C2=C(N(N=C2C)C)C)NC(=O)C3=CC=C(C=C3)OCC4=CC=CC=N4	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BL9D4X	Methyl 5-(2-(isoquinolin-5-yl)acetamido)thiazole-4-carboxylate	Investigative	52944909	C16H13N3O3S	327.4	COC(=O)C1=C(SC=N1)NC(=O)CC2=CC=CC3=C2C=CN=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BLG4W6	N-[4-Methyl-3-(1h-1,2,4-Triazol-5-Yl)thiophen-2-Yl]-2-(2-Oxo-3,4-Dihydroquinolin-1(2h)-Yl)acetamide	Investigative	46869741	C18H17N5O2S	367.4	CC1=CSC(=C1C2=NC=NN2)NC(=O)CN3C(=O)CCC4=CC=CC=C43	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BLN4I2	1-Ethyl-3-[3-(3-methylanilino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881843	C17H18N6O	322.4	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC=CC(=C3)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BM0LT9	N-Benzyl-4-(2-cyanophenoxy)benzamide	Investigative	118725451	C21H16N2O2	328.4	C1=CC=C(C=C1)CNC(=O)C2=CC=C(C=C2)OC3=CC=CC=C3C#N	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BMP0C7	Tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605037	C25H33N7O3	479.6	CC(C)(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BMTS94	6-Methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile	Investigative	45375866	C29H30N6O2S	526.7	CC1=C(C=CC2=C1C=CN2)NC3=C(C(=NC=C3C#N)C)/C=C/C4=CC(=CC=C4)S(=O)(=O)N5CCN(CC5)C	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BN6IQ1	N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydro-1,5-naphthyridin-1(2H)-yl)acetamide	Investigative	56661803	C16H13BrN6O2S	433.3	C1CC(=O)N(C2=C1N=CC=C2)CC(=O)NC3=C(C(=CS3)Br)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BNA26F	(3S,5E)-1-Methyl-3-(pyridin-2-ylmethyl)-5-(pyridin-2-ylmethylidene)piperidin-4-one	Investigative	71720141	C18H19N3O	293.4	CN1C[C@@H](C(=O)/C(=C/C2=CC=CC=N2)/C1)CC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BNA72F	1-[3-(4-Aminophenyl)pyrido[2,3-b]pyrazin-6-yl]-3-methylthiourea	Investigative	16730347	C15H14N6S	310.4	CNC(=S)NC1=NC2=NC(=CN=C2C=C1)C3=CC=C(C=C3)N	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BNHC98	2-{[3,4-Dioxo-2-(pyridin-4-ylamino)cyclobut-1-en-1-yl]amino}-2-phenylacetamide	Investigative	25206064	C17H14N4O3	322.32	C1=CC=C(C=C1)C(C(=O)N)NC2=C(C(=O)C2=O)NC3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BNL8G3	n-(4-Bromo-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(quinolin-5-yl)acetamide	Investigative	46869879	C17H12BrN5OS	414.3	C1=CC(=C2C=CC=NC2=C1)CC(=O)NC3=C(C(=CS3)Br)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BNP19V	1-Methyl-3,5-bis-pyridin-2-ylmethylene-piperidin-4-one	Investigative	2132479	C18H17N3O	291.3	CN1C/C(=C\\C2=CC=CC=N2)/C(=O)/C(=C/C3=CC=CC=N3)/C1	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BNX7Z1	8-(2,4-Difluorophenylamino)-1-methoxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one	Investigative	45280640	C22H17F2NO2	365.4	COC1=CC=CC2=C1CCC3=C(C2=O)C=CC(=C3)NC4=C(C=C(C=C4)F)F	IC50 = 78700 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BO4N1A	N=1C2=NC(NC(=S)Ncc)=CC=C2N=CC=1C1=CC=C(O)C=C1	Investigative	136125935	C16H15N5OS	325.4	CCNC(=S)NC1=NC2=NC(=CN=C2C=C1)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BO5W2I	3-(2-(Cyclopropylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53325284	C20H17N5O	343.4	C1CC1NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BO63BH	5-[2-(Cyclohexylamino)pyridin-4-Yl]-4-Naphthalen-2-Yl-2-(Tetrahydro-2h-Pyran-4-Yl)-2,4-Dihydro-3h-1,2,4-Triazol-3-One	Investigative	50941538	C28H31N5O2	469.6	C1CCC(CC1)NC2=NC=CC(=C2)C3=NN(C(=O)N3C4=CC5=CC=CC=C5C=C4)C6CCOCC6	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BO83VI	N-[4-Methyl-3-[2-methyl-6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3-yl]phenyl]benzamide	Investigative	70690018	C28H29N5O2	467.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2)N3C(=NC4=C(C3=O)C=C(C=C4)N5CCN(CC5)C)C	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BO8K3Q	5-Methoxy-2-(5-nitrothiazol-2-ylthio)benzo[d]thiazole	Investigative	44156975	C11H7N3O3S3	325.4	COC1=CC2=C(C=C1)SC(=N2)SC3=NC=C(S3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BOF7J3	4-(Naphthalen-2-yl)-3-(2-(pyridin-2-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53317413	C22H16N6O	380.4	C1=CC=C2C=C(C=CC2=C1)N3C(=NNC3=O)C4=CC(=NC=C4)NC5=CC=CC=N5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BP1RY8	1-N-[3-Chloro-4-[(2-methylphenyl)methyl]phenyl]-4-fluorobenzene-1,2-diamine	Investigative	44368287	C20H18ClFN2	340.8	CC1=CC=CC=C1CC2=C(C=C(C=C2)NC3=C(C=C(C=C3)F)N)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BP3S8R	(NE)-N-[(5-amino-1-phenylpyrazol-4-yl)-phenylmethylidene]hydroxylamine	Investigative	44408608	C16H14N4O	278.31	C1=CC=C(C=C1)/C(=N\\O)/C2=C(N(N=C2)C3=CC=CC=C3)N	IC50 = 51000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BPMA30	3-(2-Amino-4-fluoroanilino)-8-(2-morpholin-4-ylethoxy)-6H-benzo[c][1]benzoxepin-11-one	Investigative	72713980	C26H26FN3O4	463.5	C1COCCN1CCOC2=CC3=C(C=C2)C(=O)C4=C(C=C(C=C4)NC5=C(C=C(C=C5)F)N)OC3	IC50 = 94800 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BPO9D8	4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-(2-pyrrolidin-1-ylethyl)benzamide	Investigative	49864785	C26H26Cl2N6O	509.4	C1CCN(C1)CCNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=C(C=C5)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BPZ32I	n-(4-Chloro-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydroquinolin-1(2h)-yl)acetamide	Investigative	46869673	C17H14ClN5O2S	387.8	C1CC(=O)N(C2=CC=CC=C21)CC(=O)NC3=C(C(=CS3)Cl)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BQ0LW1	1-Ethyl-3-[3-(3-methoxy-4-methylanilino)pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881846	C18H20N6O2	352.4	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=C(C=C3)C)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BQ5LG8	(3R,5E)-1-Methyl-3-(pyridin-2-ylmethyl)-5-(pyridin-2-ylmethylidene)piperidin-4-one	Investigative	71718330	C18H19N3O	293.4	CN1C[C@H](C(=O)/C(=C/C2=CC=CC=N2)/C1)CC3=CC=CC=N3	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BQJL97	n-(4-Chloro-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(quinolin-5-yl)acetamide	Investigative	46869816	C17H12ClN5OS	369.8	C1=CC(=C2C=CC=NC2=C1)CC(=O)NC3=C(C(=CS3)Cl)C4=NC=NN4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BQPT64	N-[5-(1,2-Dimethylimidazol-4-yl)-2-methylphenyl]-4-(pyridin-2-ylmethoxy)benzamide	Investigative	70682196	C25H24N4O2	412.5	CC1=C(C=C(C=C1)C2=CN(C(=N2)C)C)NC(=O)C3=CC=C(C=C3)OCC4=CC=CC=N4	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BQSB36	N-(2-Methyl-5-phenylmethoxyphenyl)-1-phenyl-5-propylpyrazole-4-carboxamide	Investigative	118725457	C27H27N3O2	425.5	CCCC1=C(C=NN1C2=CC=CC=C2)C(=O)NC3=C(C=CC(=C3)OCC4=CC=CC=C4)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BQUZ09	4-[6-[(3-Chlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide	Investigative	49865153	C25H25ClN6O	461	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=CC=C5)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BRX58O	Occccnc(=O)NC=1C=CC=2C(=NC(=CN2)C2=CC(=C(C=C2)O)OC)N1	Investigative	136125936	C19H21N5O4	383.4	COC1=C(C=CC(=C1)C2=CN=C3C=CC(=NC3=N2)NC(=O)NCCCCO)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BS5YK2	Ethyl 2-[5-[4-(4-fluorophenyl)-1-methyl-5-pyridin-4-ylimidazol-2-yl]triazol-1-yl]acetate	Investigative	76325325	C21H19FN6O2	406.4	CCOC(=O)CN1C(=CN=N1)C2=NC(=C(N2C)C3=CC=NC=C3)C4=CC=C(C=C4)F	IC50 = 56000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BS6XU0	1-[3-(3,5-Dimethoxyanilino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881892	C18H20N6O3	368.4	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=CC(=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BS78ZR	3-(2,4-Difluoroanilino)-7-(2-morpholin-4-ylethoxy)-5,6-dihydrodibenzo[3,1-[7]annulen-11-one	Investigative	45280695	C27H26F2N2O3	464.5	C1CC2=C(C=CC=C2OCCN3CCOCC3)C(=O)C4=C1C=C(C=C4)NC5=C(C=C(C=C5)F)F	IC50 = 200000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BSC6A4	Methyl 3-(2-(isoquinolin-5-yl)acetamido)thiophene-2-carboxylate	Investigative	52949817	C17H14N2O3S	326.4	COC(=O)C1=C(C=CS1)NC(=O)CC2=CC=CC3=C2C=CN=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BSY2Z6	4-(Naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1-(tetrahydrofuran-3-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53317416	C26H27N5O3	457.5	C1COCCC1NC2=NC=CC(=C2)C3=NN(C(=O)N3C4=CC5=CC=CC=C5C=C4)C6CCOC6	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BT0C4K	2-(4-Methoxyphenyl)-N-(2-(2-methyl-1H-imidazol-4-yl)thiophen-3-yl)acetamide	Investigative	52946092	C17H17N3O2S	327.4	CC1=NC=C(N1)C2=C(C=CS2)NC(=O)CC3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BTO6K2	8-(2-Aminophenylamino)-1-methoxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one	Investigative	45280641	C22H20N2O2	344.4	COC1=CC=CC2=C1CCC3=C(C2=O)C=CC(=C3)NC4=CC=CC=C4N	IC50 = 52100 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BU2XZ7	N=1C2=NC(NC(=O)Ncc)=CC=C2N=CC=1NC1=CC=C(O)C=C1	Investigative	136125938	C16H16N6O2	324.34	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BU37PF	2-(4-Methoxyphenyl)-N-(2-(pyrazin-2-yl)thiophen-3-yl)acetamide	Investigative	52941286	C17H15N3O2S	325.4	COC1=CC=C(C=C1)CC(=O)NC2=C(SC=C2)C3=NC=CN=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BU4D1O	2-(Isoquinolin-5-yl)-N-(2-(thiazol-4-yl)thiophen-3-yl)acetamide	Investigative	46868930	C18H13N3OS2	351.4	C1=CC2=C(C=CN=C2)C(=C1)CC(=O)NC3=C(SC=C3)C4=CSC=N4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BU5JP9	4-(Naphthalen-2-yl)-1-(pyridin-2-ylmethyl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53325283	C28H26N6O2	478.5	C1COCCC1NC2=NC=CC(=C2)C3=NN(C(=O)N3C4=CC5=CC=CC=C5C=C4)CC6=CC=CC=N6	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BU6KL3	n-(4-Methyl-3-(1h-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(quinolin-5-yl)acetamide	Investigative	46869745	C18H15N5OS	349.4	CC1=CSC(=C1C2=NC=NN2)NC(=O)CC3=C4C=CC=NC4=CC=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BUB5D8	1-Ethyl-3-[3-[4-(3-morpholin-4-ylpropoxy)phenyl]pyrido[2,3-b]pyrazin-6-yl]urea	Investigative	58881834	C23H28N6O3	436.5	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC=C(C=C3)OCCCN4CCOCC4	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BUL13X	2,4-Bis(1,3-benzodioxol-5-yl)-4-oxobutanoic acid	Investigative	294348	C18H14O7	342.3	C1OC2=C(O1)C=C(C=C2)C(CC(=O)C3=CC4=C(C=C3)OCO4)C(=O)O	IC50 = 197000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BUN72C	(S)-2-(2-Aminophenylamino)-8-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one	Investigative	45280586	C27H28N2O4	444.5	CC1(OC[C@@H](O1)COC2=CC3=C(C=C2)C(=O)C4=C(CC3)C=C(C=C4)NC5=CC=CC=C5N)C	IC50 = 93600 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BUW40I	1-[3-(3-Chloro-4-methoxyanilino)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881810	C17H17ClN6O2	372.8	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)NC3=CC(=C(C=C3)OC)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BUX54L	(S)-8-(2-Aminophenylamino)-1-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one	Investigative	45280692	C27H28N2O4	444.5	CC1(OC[C@@H](O1)COC2=CC=CC3=C2CCC4=C(C3=O)C=CC(=C4)NC5=CC=CC=C5N)C	IC50 = 158000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BV6A1G	6-(2,4-Difluoroanilino)-12-(oxan-4-yl)tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaen-2-one	Investigative	71449477	C26H23F2NO2	419.5	C1COCCC1C2=C3CCC4=C(C=CC(=C4)NC5=C(C=C(C=C5)F)F)C(=O)C3=CC=C2	IC50 = 87200 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BV8F4S	4-(Benzyloxy)-1-(3-fluorobenzyl)-3-(trifluoromethyl)pyridin-2(1H)-one	Investigative	22050442	C20H15F4NO2	377.3	C1=CC=C(C=C1)COC2=C(C(=O)N(C=C2)CC3=CC(=CC=C3)F)C(F)(F)F	IC50 = 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BVDF78	(S)-4-(6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide	Investigative	46933384	C22H26N6O	390.5	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5CC5	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BVI90B	Chembl4276946	Investigative	134611886	C12H11Cl2N3O	284.14	CC1=NN(C(=C1C2=CC(=C(C=C2)Cl)Cl)N)C(=O)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BVIM01	2-Benzyl-5-(benzyloxy)-4-bromopyridazin-3(2H)-one	Investigative	46887066	C18H15BrN2O2	371.2	C1=CC=C(C=C1)CN2C(=O)C(=C(C=N2)OCC3=CC=CC=C3)Br	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BW3U0R	2-(5-Nitrothiazol-2-ylthio)benzo[d]thiazole	Investigative	44156976	C10H5N3O2S3	295.4	C1=CC=C2C(=C1)N=C(S2)SC3=NC=C(S3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BW65NQ	4-(Naphthalen-2-yl)-3-(2-(phenylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53326556	C23H17N5O	379.4	C1=CC=C(C=C1)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BWN6O5	1-[3-(3,5-Dimethyl-1H-pyrazol-4-yl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881876	C15H17N7O	311.34	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=C(NN=C3C)C	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BWSK97	4-(6-Fluoronaphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53322645	C22H20FN5O2	405.4	C1COCCC1NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=C(C=C4)C=C(C=C5)F	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BWY3P1	4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide	Investigative	49864850	C25H24Cl2N6O	495.4	C1C[C@H](NC1)CNC(=O)C2=CC=C(C=C2)C3=CN=C4N3N=C(C=C4)NCC5=CC(=C(C=C5)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BX1M0U	1-[3-(3,4-Dimethoxyphenyl)pyrido[2,3-b]pyrazin-6-yl]-3-ethylurea	Investigative	58881858	C18H19N5O3	353.4	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=C(C=C3)OC)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BX26EG	Methyl 3-[2-(2-thienyl)acetamido]thiophene-2-carboxylate	Investigative	2808202	C12H11NO3S2	281.4	COC(=O)C1=C(C=CS1)NC(=O)CC2=CC=CS2	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BX4BY3	Dithioether 1,3,4-thiadiazole, 8f	Investigative	20333093	C8H2N6O4S5	406.5	C1=C(SC(=N1)SC2=NN=C(S2)SC3=NC=C(S3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BXUQ08	3-(2-(Cyclopentylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53322644	C22H21N5O	371.4	C1CCC(C1)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BXV2Y0	C(C)NC(=O)NC=1C=CC=2C(=NC(=CN2)C2=CC(=C(C=C2)O)OC)N1	Investigative	136125931	C17H17N5O3	339.3	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=C(C=C3)O)OC	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BY0EP8	3-(2-(Cyclobutylamino)pyridin-4-yl)-4-(naphthalen-2-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53323986	C21H19N5O	357.4	C1CC(C1)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BY0TR9	2-(4-Methoxyphenyl)-N-(2-(1-methyl-1H-imidazol-4-yl)thiophen-3-yl)acetamide	Investigative	52948565	C17H17N3O2S	327.4	CN1C=C(N=C1)C2=C(C=CS2)NC(=O)CC3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BY15FU	(R)-8-(2,4-Difluorophenylamino)-1-(2,3-dihydroxypropoxy)-10,11-dihydrodibenzo-[a,d]cyclohepten-5-one	Investigative	45280643	C24H21F2NO4	425.4	C1CC2=C(C=CC=C2OC[C@@H](CO)O)C(=O)C3=C1C=C(C=C3)NC4=C(C=C(C=C4)F)F	IC50 = 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BY32PN	3-[6-(Ethylcarbamoylamino)pyrido[2,3-b]pyrazin-3-yl]benzamide	Investigative	58881836	C17H16N6O2	336.3	CCNC(=O)NC1=NC2=NC(=CN=C2C=C1)C3=CC(=CC=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BY6LN3	5-Methyl-1-[4-(2-piperidin-1-ylethoxy)phenyl]pyridin-2-one	Investigative	71543197	C19H24N2O2	312.4	CC1=CN(C(=O)C=C1)C2=CC=C(C=C2)OCCN3CCCCC3	IC50 = 54310 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BYUV62	3-(2-Aminoanilino)-8-(2-morpholin-4-ylethoxy)-6H-benzo[c][1]benzoxepin-11-one	Investigative	72713979	C26H27N3O4	445.5	C1COCCN1CCOC2=CC3=C(C=C2)C(=O)C4=C(C=C(C=C4)NC5=CC=CC=C5N)OC3	IC50 = 58730 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BZ4H3B	4-(Naphthalen-2-yl)-3-(2-(tetrahydro-2H-pyran-3-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53326555	C22H21N5O2	387.4	C1CC(COC1)NC2=NC=CC(=C2)C3=NNC(=O)N3C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	BZ4S6R	4-(Naphthalen-2-yl)-1-(pyridin-2-yl)-3-(2-(tetrahydro-2H-pyran-4-ylamino)pyridin-4-yl)-1H-1,2,4-triazol-5(4H)-one	Investigative	53325286	C27H24N6O2	464.5	C1COCCC1NC2=NC=CC(=C2)C3=NN(C(=O)N3C4=CC5=CC=CC=C5C=C4)C6=CC=CC=N6	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D01YWE	PMID19364658C33	Investigative	25207521	C17H14N4O4	338.32	C1=CC(=CC(=C1)O)C(C(=O)N)NC2=C(C(=O)C2=O)NC3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D03MUZ	8-chloro-quinoline-3-carbonitrile	Investigative	17759555	C20H13Cl2FN6	427.3	C1=CC(=C(C=C1NC2=C3C=C(C=C(C3=NC=C2C#N)Cl)NCC4=CN=CN4)Cl)F	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D06LJL	PMID16451062C46	Investigative	9916282	C29H33FN6O4S	580.7	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=NC=C(S3)CC(=O)NC4=CC(=CC=C4)F)OCCCN5CCC(CC5)CO	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D0EW9J	PMID17480064C16	Investigative	10389239	C21H16N4O	340.4	C1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4	IC50 ~ 100000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D0GD8Y	U0126	Investigative	3006531	C18H16N6S2	380.5	C1=CC=C(C(=C1)N)S/C(=C(/C(=C(/SC2=CC=CC=C2N)\\N)/C#N)\\C#N)/N	IC50 = 55000 nM	Poor binder
T65864	Stress-activated protein kinase 2a	D0XB4P	HTS-466284	Investigative	447966	C17H12N4	272.3	C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4	IC50 = 51000 nM	Poor binder