TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T73342	Ribonucleotide reductase	B16WQB	2-[3-Carboxy-2-(2-{3-methyl-2-[2-(3-phenyl-propionylamino)-acetylamino]-butyrylamino}-4-oxo-4-pyrrolidin-1-yl-butyrylamino)-propionylamino]-4-methyl-pentanoic acid	Investigative	512999	C34H50N6O10	702.8	CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(=O)N1CCCC1)NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)CCC2=CC=CC=C2	IC50 = 115000 nM	Poor binder
T73342	Ribonucleotide reductase	B25FPS	1-[[2-(3,3-Dimethyl-2-{3-methyl-2-[methyl-(3-phenyl-propionyl)-amino]-butyrylamino}-butyrylamino)-4-oxo-4-pyrrolidin-1-yl-butyrylamino]-(1-hydroxymethyl-3,3-dimethyl-butylcarbamoyl)-methyl]-cyclopentanecarboxylic acid	Investigative	513005	C44H70N6O9	827.1	CC(C)[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)N1CCCC1)C(=O)N[C@H](C(=O)N[C@@H](CC(C)(C)C)CO)C2(CCCC2)C(=O)O)C(C)(C)C)N(C)C(=O)CCC3=CC=CC=C3	EC50 = 52000 nM	Poor binder
T73342	Ribonucleotide reductase	BA8KT2	(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-3-carbamoyl-propionylamino)-3-carboxy-propionylamino]-4-methyl-pentanoic acid	Investigative	512986	C27H47N7O10	629.7	C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)O)N	IC50 = 58000 nM	Poor binder
T73342	Ribonucleotide reductase	BLC28H	(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-Acetamido-3-(4-azidophenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid	Investigative	56664763	C41H54N10O14	910.9	C[C@@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)N=[N+]=[N-])NC(=O)C)O	IC50 = 100000 nM	Poor binder
T73342	Ribonucleotide reductase	BV6EO1	(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-Amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid	Investigative	56678438	C42H58N8O15	915	C[C@@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CO)N)O	IC50 = 80000 nM	Poor binder
T73342	Ribonucleotide reductase	BVEJ49	(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-Acetamido-3-(4-aminophenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-4-[[(1S)-1-carboxy-2-phenylethyl]amino]-4-oxobutanoic acid	Investigative	56664823	C41H56N8O14	884.9	C[C@@H]([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)N)NC(=O)C)O	IC50 = 100000 nM	Poor binder
T73342	Ribonucleotide reductase	BZK61D	1-[[2-(2-{2-[(2-Benzyl-3-phenyl-propionyl)-methyl-amino]-3-methyl-butyrylamino}-3,3-dimethyl-butyrylamino)-3-carbamoyl-propionylamino]-(1-hydroxymethyl-3,3-dimethyl-butylcarbamoyl)-methyl]-cyclopentanecarboxylic acid	Investigative	513008	C47H70N6O9	863.1	CC(C)[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@H](C(=O)N[C@@H](CC(C)(C)C)CO)C1(CCCC1)C(=O)O)C(C)(C)C)N(C)C(=O)C(CC2=CC=CC=C2)CC3=CC=CC=C3	EC50 = 150000 nM	Poor binder