TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T73495	Glutamate receptor ionotropic kainate 1	D00ENY	L-Glutamic Acid	Approved	33032	C5H9NO4	147.13	C(CC(=O)O)[C@@H](C(=O)O)N	EC50 = 75000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	B4BLW1	4-Chloro-2-(pyridin-4-ylcarbamoylamino)benzoic Acid	Investigative	10402054	C13H10ClN3O3	291.69	C1=CC(=C(C=C1Cl)NC(=O)NC2=CC=NC=C2)C(=O)O	IC50 = 88000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	B56JSQ	2-Methyl-6-[[3-(trifluoromethyl)phenyl]carbamoylamino]benzoic Acid	Investigative	10131929	C16H13F3N2O3	338.28	CC1=C(C(=CC=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	B6JV5Y	2-[(Anilinocarbonyl)amino]benzoic acid	Investigative	220181	C14H12N2O3	256.26	C1=CC=C(C=C1)NC(=O)NC2=CC=CC=C2C(=O)O	IC50 ~ 100000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	B6TL4P	4-Chloro-2-(3-pyridin-3-yl-ureido)-benzoic acid	Investigative	11449212	C13H10ClN3O3	291.69	C1=CC(=CN=C1)NC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O	IC50 = 69000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	B9R0WX	5-Methyl-2-[[3-(trifluoromethyl)phenyl]carbamoylamino]benzoic Acid	Investigative	10268727	C16H13F3N2O3	338.28	CC1=CC(=C(C=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)C(=O)O	IC50 ~ 100000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BD41BU	4-Chloro-2-(naphthalen-2-ylcarbamoylamino)benzoic Acid	Investigative	10132082	C18H13ClN2O3	340.8	C1=CC=C2C=C(C=CC2=C1)NC(=O)NC3=C(C=CC(=C3)Cl)C(=O)O	IC50 = 69000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BEPF19	N-(3-Bromophenyl)-6-chloro-3-hydroxy-1H-indazole-1-carboxamide	Investigative	11428576	C14H9BrClN3O2	366.6	C1=CC(=CC(=C1)Br)NC(=O)N2C3=C(C=CC(=C3)Cl)C(=O)N2	IC50 ~ 50000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BHV06S	4-Chloro-2-(3-thiophen-3-yl-ureido)-benzoic acid	Investigative	11415238	C12H9ClN2O3S	296.73	C1=CC(=C(C=C1Cl)NC(=O)NC2=CSC=C2)C(=O)O	IC50 = 51000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BK3MJ6	Anthranilic acid, N-((alpha,alpha,alpha-trifluoro-m-tolyl)carbamoyl)-	Investigative	9883705	C15H11F3N2O3	324.25	C1=CC=C(C(=C1)C(=O)O)NC(=O)NC2=CC=CC(=C2)C(F)(F)F	IC50 = 72000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BN6UO3	(3S,4Ar,6S,8aR)-6-[(2-carboxyphenyl)methyl]-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid;hydrochloride	Investigative	73348020	C18H24ClNO4	353.8	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1CC3=CC=CC=C3C(=O)O)C(=O)O.Cl	Ki = 67000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BOJ18K	3-[3-(3-Trifluoromethyl-phenyl)-ureido]-naphthalene-2-carboxylic acid	Investigative	10177391	C19H13F3N2O3	374.3	C1=CC=C2C=C(C(=CC2=C1)C(=O)O)NC(=O)NC3=CC=CC(=C3)C(F)(F)F	IC50 = 60000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BR0DB3	4-Chloro-2-(cyclohexylcarbamoylamino)benzoic Acid	Investigative	10334760	C14H17ClN2O3	296.75	C1CCC(CC1)NC(=O)NC2=C(C=CC(=C2)Cl)C(=O)O	IC50 ~ 100000 nM	Poor binder
T73495	Glutamate receptor ionotropic kainate 1	BR1JT0	3-Methyl-2-[[3-(trifluoromethyl)phenyl]carbamoylamino]benzoic Acid	Investigative	10268728	C16H13F3N2O3	338.28	CC1=C(C(=CC=C1)C(=O)O)NC(=O)NC2=CC=CC(=C2)C(F)(F)F	IC50 ~ 100000 nM	Poor binder