TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T74570	Inward rectifier potassium channel Kir2.1	B0OW6Y	5-[2-[4-[2-[4-(Tetrazol-1-yl)phenyl]acetyl]piperazin-1-yl]ethyl]-3H-2-benzofuran-1-one	Investigative	57331209	C23H24N6O3	432.5	C1CN(CCN1CCC2=CC3=C(C=C2)C(=O)OC3)C(=O)CC4=CC=C(C=C4)N5C=NN=N5	IC50 ~ 50000 nM	Poor binder
T74570	Inward rectifier potassium channel Kir2.1	B2A0FE	8-[(2R)-2-Hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-2-(1-methyl-6-oxopyridazin-3-yl)-2,8-diazaspiro[4.5]decan-1-one	Investigative	121313969	C24H28N4O5	452.5	CC1=C(C=CC2=C1COC2=O)[C@H](CN3CCC4(CC3)CCN(C4=O)C5=NN(C(=O)C=C5)C)O	IC50 ~ 100000 nM	Poor binder
T74570	Inward rectifier potassium channel Kir2.1	B3TL6G	6-[(1S)-1-Hydroxy-2-[4-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]piperazin-1-yl]ethyl]-4-methoxypyridine-3-carbonitrile	Investigative	59568656	C24H28N4O5	452.5	CC1=C(C=CC2=C1COC2=O)[C@H](CN3CCN(CC3)C[C@@H](C4=NC=C(C(=C4)OC)C#N)O)O	IC50 ~ 50000 nM	Poor binder
T74570	Inward rectifier potassium channel Kir2.1	BJC93H	1,4-Bis[2-(4-nitrophenyl)ethyl]piperazine	Investigative	52337837	C20H24N4O4	384.4	C1CN(CCN1CCC2=CC=C(C=C2)[N+](=O)[O-])CCC3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T74570	Inward rectifier potassium channel Kir2.1	BPFN07	1-[2-(4-Nitrophenyl)ethyl]piperazine	Investigative	14985965	C12H17N3O2	235.28	C1CN(CCN1)CCC2=CC=C(C=C2)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T74570	Inward rectifier potassium channel Kir2.1	BPN5S3	4-Methyl-5-[2-[4-[2-[6-(tetrazol-1-yl)pyridin-3-yl]acetyl]piperazin-1-yl]ethyl]-3H-2-benzofuran-1-one	Investigative	57331668	C23H25N7O3	447.5	CC1=C(C=CC2=C1COC2=O)CCN3CCN(CC3)C(=O)CC4=CN=C(C=C4)N5C=NN=N5	IC50 ~ 50000 nM	Poor binder
T74570	Inward rectifier potassium channel Kir2.1	BSEF80	Auglurant	Investigative	60168069	C16H12FN5O2	325.3	CC1=CC(=CC(=N1)C(=O)NC2=NC=C(C=C2)F)OC3=CN=CN=C3	IC50 ~ 100000 nM	Poor binder
T74570	Inward rectifier potassium channel Kir2.1	BZWC49	6-Fluoro-2-methyl-3-[(3R,9sS)-octahydro-8-[2-[5-(1H-tetrazol-1-yl)-2-pyridinyl]acetyl]pyrazino[2.1=c][1.4]oxazin-3-yl]benzonitrile	Investigative	71603917	C23H23FN8O2	462.5	CC1=C(C=CC(=C1C#N)F)[C@@H]2CN3CCN(C[C@H]3CO2)C(=O)CC4=NC=C(C=C4)N5C=NN=N5	IC50 ~ 100000 nM	Poor binder