TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T76685	Cannabinoid receptor 1	D0E6YT	PMID27215781-Compound-27	Patented	71539748	C21H12N6O2S	412.4	C1=CC=C(C(=C1)CSC2=NC3=C(C4=CC=CC=C4N3C(=O)C5=CC=NO5)N=N2)C#N	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	B05DJB	2-Methyl-6-(4-methyl-1-piperazinyl)-8-(2-chlorophenyl)-9-[(3S)-tetrahydrofuran-3beta-yl]-9H-purine	Investigative	46834060	C21H25ClN6O	412.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2[C@H]4CCOC4)C5=CC=CC=C5Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B0A1UZ	8-(2-Chlorophenyl)-9-cyclopropyl-2-methyl-6-(4-methylpiperazin-1-yl)purine;hydrochloride	Investigative	76335394	C20H24Cl2N6	419.3	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C4CC4)C5=CC=CC=C5Cl.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B0QXV1	2-Methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)-8-[2-(trifluoromethyl)phenyl]purine;hydrochloride	Investigative	68603806	C23H28ClF3N6O	497	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C4CCOCC4)C5=CC=CC=C5C(F)(F)F.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B0SE9X	8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-2-methyl-9-(oxan-4-ylmethyl)purine;hydrochloride	Investigative	67425523	C24H32Cl2N6O	491.5	CCN1CCN(CC1)C2=NC(=NC3=C2N=C(N3CC4CCOCC4)C5=CC=CC=C5Cl)C.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B16JVX	(2S)-N-(3-Tert-butyl-1,2-oxazol-5-yl)-1-(4-cyanophenyl)-5-oxopyrrolidine-2-carboxamide	Investigative	46843358	C19H20N4O3	352.4	CC(C)(C)C1=NOC(=C1)NC(=O)[C@@H]2CCC(=O)N2C3=CC=C(C=C3)C#N	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	B1FI0X	1-[2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]ethyl]pyrrolidin-2-one	Investigative	62705989	C23H28ClN7O	454	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2CCN4CCCC4=O)C5=CC=CC=C5Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B1K4XJ	3-[(2-Nitrophenyl)methylsulfanyl]-5H-[1,2,4]triazino[5,6-b]indole	Investigative	8916493	C16H11N5O2S	337.4	C1=CC=C(C(=C1)CSC2=NC3=C(C4=CC=CC=C4N3)N=N2)[N+](=O)[O-]	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	B1RX3T	(2S)-N-(5-Tert-butyl-1,3,4-thiadiazol-2-yl)-1-(oxan-4-yl)pyrrolidine-2-carboxamide	Investigative	67953351	C16H26N4O2S	338.5	CC(C)(C)C1=NN=C(S1)NC(=O)[C@@H]2CCCN2C3CCOCC3	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	B24OKY	8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3R)-oxolan-3-yl]purine;hydrochloride	Investigative	60149000	C21H26Cl2N6O	449.4	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2[C@@H]4CCOC4)C5=CC=CC=C5Cl.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B2E4AN	6-(4-Methyl-1-piperazinyl)-8-(2-chlorophenyl)-9-[(3R)-tetrahydrofuran-3-yl]-2-methyl-9H-purine	Investigative	46220521	C21H25ClN6O	412.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2[C@@H]4CCOC4)C5=CC=CC=C5Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B2EL4U	2-[[5-[(2-Nitrophenyl)methyl]-[1,2,4]triazino[5,6-b]indol-3-yl]sulfanylmethyl]benzonitrile	Investigative	71539585	C24H16N6O2S	452.5	C1=CC=C(C(=C1)CN2C3=CC=CC=C3C4=C2N=C(N=N4)SCC5=CC=CC=C5C#N)[N+](=O)[O-]	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	B2QIJ6	(2R)-2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]propan-1-ol	Investigative	53476894	C20H25ClN6O	400.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2[C@H](C)CO)C4=CC=CC=C4Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B3BQ5A	Methyl 4-[3-[(2-cyanophenyl)methylsulfanyl]-[1,2,4]triazino[5,6-b]indol-5-yl]-4-oxobutanoate	Investigative	71539750	C22H17N5O3S	431.5	COC(=O)CCC(=O)N1C2=CC=CC=C2C3=C1N=C(N=N3)SCC4=CC=CC=C4C#N	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	B3WE7C	(2S)-N-(5-Tert-butyl-1,2-oxazol-3-yl)-1-cyclobutylpyrrolidine-2-carboxamide	Investigative	67953301	C16H25N3O2	291.39	CC(C)(C)C1=CC(=NO1)NC(=O)[C@@H]2CCCN2C3CCC3	EC50 = 98005 nM	Poor binder
T76685	Cannabinoid receptor 1	B3Z1TS	Benzenesulfonamide, N-[(2Z)-5-(1,1-dimethylethyl)-3,4-dimethyl-2(3H)-thiazolylidene]-	Investigative	5722610	C15H20N2O2S2	324.5	CC1=C(S/C(=N\\S(=O)(=O)C2=CC=CC=C2)/N1C)C(C)(C)C	IC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	B3ZB1S	8-(2-Chlorophenyl)-9-cyclopropyl-2-methyl-6-(4-methylpiperazin-1-yl)purine	Investigative	62705987	C20H23ClN6	382.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C4CC4)C5=CC=CC=C5Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B45LXK	(2S)-N-(3-Tert-butyl-1,2-oxazol-5-yl)-1-(4-chlorophenyl)-5-oxopyrrolidine-2-carboxamide	Investigative	46843431	C18H20ClN3O3	361.8	CC(C)(C)C1=NOC(=C1)NC(=O)[C@@H]2CCC(=O)N2C3=CC=C(C=C3)Cl	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	B46SBX	1-[2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]ethyl]pyrrolidin-2-one;hydrochloride	Investigative	71138232	C23H29Cl2N7O	490.4	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2CCN4CCCC4=O)C5=CC=CC=C5Cl.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B4X0ZY	2-Methyl-4-(4-methyl-1-piperidinyl)-6-phenylthieno[2,3-d]pyrimidine	Investigative	853260	C19H21N3S	323.5	CC1CCN(CC1)C2=C3C=C(SC3=NC(=N2)C)C4=CC=CC=C4	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B68VJO	8-(2-Chlorophenyl)-6-[4-(2-fluoroethyl)piperazin-1-yl]-9-(2-methoxyethyl)-2-methylpurine;hydrochloride	Investigative	71764824	C21H27Cl2FN6O	469.4	CC1=NC2=C(C(=N1)N3CCN(CC3)CCF)N=C(N2CCOC)C4=CC=CC=C4Cl.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B6YS4O	2-[[5-(Cyclohexanecarbonyl)-[1,2,4]triazino[5,6-b]indol-3-yl]sulfanylmethyl]benzonitrile	Investigative	71539693	C24H21N5OS	427.5	C1CCC(CC1)C(=O)N2C3=CC=CC=C3C4=C2N=C(N=N4)SCC5=CC=CC=C5C#N	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	B7PC2H	(2S,4S)-9-(4-Oxidopyrazin-4-ium-2-yl)-N-(1-pyridin-2-ylcyclobutyl)-8,9-diazatricyclo[4.3.0.02,4]non-7-ene-7-carboxamide	Investigative	90654972	C21H22N6O2	390.4	C1CC(C1)(C2=CC=CC=N2)NC(=O)C3=NN(C4C3C[C@H]5[C@@H]4C5)C6=NC=C[N+](=C6)[O-]	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	B92CML	8-(2-Ethylphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)purine;hydrochloride	Investigative	68604800	C24H33ClN6O	457	CCC1=CC=CC=C1C2=NC3=C(N2C4CCOCC4)N=C(N=C3N5CCN(CC5)C)C.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	B9UW2P	2-[[5-[4-(Trifluoromethoxy)benzoyl]-[1,2,4]triazino[5,6-b]indol-3-yl]sulfanylmethyl]benzonitrile	Investigative	71539696	C25H14F3N5O2S	505.5	C1=CC=C(C(=C1)CSC2=NC3=C(C4=CC=CC=C4N3C(=O)C5=CC=C(C=C5)OC(F)(F)F)N=N2)C#N	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	BA20BP	N-[3-(2-Hydroxy-1,1-dimethyl-ethyl)-isoxazol-5-yl]-2-methyl-2-(tetrahydro-pyran-4-sulfonyl)-propionamide	Investigative	45256133	C16H26N2O6S	374.5	CC(C)(CO)C1=NOC(=C1)NC(=O)C(C)(C)S(=O)(=O)C2CCOCC2	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BD8J3S	N-[2-(Cyclobutylmethylcarbamoyl)-6-(2-hydroxyethoxy)pyridin-3-yl]quinoline-4-carboxamide	Investigative	71546834	C23H24N4O4	420.5	C1CC(C1)CNC(=O)C2=C(C=CC(=N2)OCCO)NC(=O)C3=CC=NC4=CC=CC=C34	IC50 = 73000 nM	Poor binder
T76685	Cannabinoid receptor 1	BDM9A7	Chembl4161451	Investigative	145956970	C26H22O4	398.4	C1=CC=C2C(=C1)C=CC=C2C(=O)C3=CC=C(C4=CC=CC=C43)OCCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BF5D9X	(2S)-N-(3-Tert-butyl-1,2-oxazol-5-yl)-1-(4-methylsulfonylphenyl)-5-oxopyrrolidine-2-carboxamide	Investigative	46843437	C19H23N3O5S	405.5	CC(C)(C)C1=NOC(=C1)NC(=O)[C@@H]2CCC(=O)N2C3=CC=C(C=C3)S(=O)(=O)C	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BF7BD6	Chembl4159535	Investigative	145959099	C27H24O4	412.5	COC(=O)CCCCOC1=CC=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BFW38Q	2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]propan-1-ol	Investigative	53386375	C20H25ClN6O	400.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C(C)CO)C4=CC=CC=C4Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BG7FM0	2-Methyl-6-(4-ethyl-1-piperazinyl)-8-(2-chlorophenyl)-9-(2-methoxyethyl)-9H-purine	Investigative	58459093	C21H27ClN6O	414.9	CCN1CCN(CC1)C2=NC(=NC3=C2N=C(N3CCOC)C4=CC=CC=C4Cl)C	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BGLP74	(2S,4R)-N-(3-Tert-butyl-1,2-oxazol-5-yl)-4-hydroxy-1-(oxan-4-ylmethyl)pyrrolidine-2-carboxamide	Investigative	67953265	C18H29N3O4	351.4	CC(C)(C)C1=NOC(=C1)NC(=O)[C@@H]2C[C@H](CN2CC3CCOCC3)O	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BGX7Q4	Chembl4167940	Investigative	145954337	C24H20O3	356.4	C1=CC=C2C(=C1)C=CC=C2C(=O)C3=CC=C(C4=CC=CC=C43)OCCCO	IC50 = 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BHB4Z2	8-(2-Chlorophenyl)-6-(4-ethylpiperazin-1-yl)-9-(2-methoxyethyl)-2-methylpurine;hydrochloride	Investigative	67434704	C21H28Cl2N6O	451.4	CCN1CCN(CC1)C2=NC(=NC3=C2N=C(N3CCOC)C4=CC=CC=C4Cl)C.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BHF4K9	8-(2-Chlorophenyl)-9-(1,3-dimethoxypropan-2-yl)-6-(4-ethylpiperazin-1-yl)-2-methylpurine	Investigative	58459090	C23H31ClN6O2	459	CCN1CCN(CC1)C2=NC(=NC3=C2N=C(N3C(COC)COC)C4=CC=CC=C4Cl)C	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BHK7J2	[3-[(2-Nitrophenyl)methylsulfanyl]-[1,2,4]triazino[5,6-b]indol-5-yl]-phenylmethanone	Investigative	71539582	C23H15N5O3S	441.5	C1=CC=C(C=C1)C(=O)N2C3=CC=CC=C3C4=C2N=C(N=N4)SCC5=CC=CC=C5[N+](=O)[O-]	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	BKQM83	N-[3-(1-Hydroxy-2-methylpropan-2-yl)-1,2-oxazol-5-yl]-2-methyl-2-[methyl(oxan-4-yl)amino]propanamide	Investigative	49848443	C17H29N3O4	339.4	CC(C)(CO)C1=NOC(=C1)NC(=O)C(C)(C)N(C)C2CCOCC2	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BL4V8R	1-((S)-1-{4-[4-Methoxy-2-(4-methoxy-benzenesulfonyl)-benzenesulfonyl]-phenyl}-ethyl)-3-propyl-urea	Investigative	44390826	C26H30N2O7S2	546.7	CCCNC(=O)N[C@@H](C)C1=CC=C(C=C1)S(=O)(=O)C2=C(C=C(C=C2)OC)S(=O)(=O)C3=CC=C(C=C3)OC	Ki = 72089 nM	Poor binder
T76685	Cannabinoid receptor 1	BL97RM	2-Methyl-8-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)purine;hydrochloride	Investigative	67425691	C23H31ClN6O	443	CC1=CC=CC=C1C2=NC3=C(N2C4CCOCC4)N=C(N=C3N5CCN(CC5)C)C.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BM28HU	2-[(5H-[1,2,4]Triazino[5,6-b]indol-3-ylsulfanyl)methyl]benzonitrile	Investigative	6401059	C17H11N5S	317.4	C1=CC=C(C(=C1)CSC2=NC3=C(C4=CC=CC=C4N3)N=N2)C#N	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	BM7X6H	Methyl N-[2-[8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]ethyl]carbamate	Investigative	62705988	C21H26ClN7O2	443.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2CCNC(=O)OC)C4=CC=CC=C4Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BNA5H0	1-(4-{2-Methyl-6-phenylthieno[2,3-d]pyrimidin-4-yl}piperazin-1-yl)ethan-1-one	Investigative	2084332	C19H20N4OS	352.5	CC1=NC(=C2C=C(SC2=N1)C3=CC=CC=C3)N4CCN(CC4)C(=O)C	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BNCP04	(2S)-N-(3-Tert-butyl-1,2-oxazol-5-yl)-5-oxo-1-[4-(trifluoromethyl)phenyl]pyrrolidine-2-carboxamide	Investigative	67953330	C19H20F3N3O3	395.4	CC(C)(C)C1=NOC(=C1)NC(=O)[C@@H]2CCC(=O)N2C3=CC=C(C=C3)C(F)(F)F	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BNIA98	1-((S)-1-{4-[4-Methoxy-2-(4-methoxy-benzenesulfonyl)-benzenesulfonyl]-phenyl}-ethyl)-3-p-tolyl-urea	Investigative	44390741	C30H30N2O7S2	594.7	CC1=CC=C(C=C1)NC(=O)N[C@@H](C)C2=CC=C(C=C2)S(=O)(=O)C3=C(C=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	Ki = 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BPJ26T	(2S,4S)-N-(3-Tert-butyl-1,2-oxazol-5-yl)-4-hydroxy-1-(oxan-4-ylmethyl)pyrrolidine-2-carboxamide	Investigative	67953329	C18H29N3O4	351.4	CC(C)(C)C1=NOC(=C1)NC(=O)[C@@H]2C[C@@H](CN2CC3CCOCC3)O	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BR27BY	8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-[(3S)-oxolan-3-yl]purine;hydrochloride	Investigative	76309966	C21H26Cl2N6O	449.4	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2[C@H]4CCOC4)C5=CC=CC=C5Cl.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BR51QV	(2S)-2-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]propan-1-ol	Investigative	118722126	C20H25ClN6O	400.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2[C@@H](C)CO)C4=CC=CC=C4Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BRU9L5	1-[8-(2-Chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)purin-9-yl]-2-methylpropan-2-ol	Investigative	58459056	C21H27ClN6O	414.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2CC(C)(C)O)C4=CC=CC=C4Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BRY1B0	N-(Cyclobutylmethyl)-3-[[4-(pyrrol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide	Investigative	11655065	C27H26N4O2	438.5	C1CC(C1)CNC(=O)C2=C(C=CC=N2)NC(=O)C3=CC=C(C4=CC=CC=C43)CN5C=CC=C5	IC50 = 89000 nM	Poor binder
T76685	Cannabinoid receptor 1	BTS43R	2-[[5-(Cyclopentanecarbonyl)-[1,2,4]triazino[5,6-b]indol-3-yl]sulfanylmethyl]benzonitrile	Investigative	71539697	C23H19N5OS	413.5	C1CCC(C1)C(=O)N2C3=CC=CC=C3C4=C2N=C(N=N4)SCC5=CC=CC=C5C#N	Ki ~ 60000 nM	Poor binder
T76685	Cannabinoid receptor 1	BUD8W7	Chembl4176556	Investigative	145972916	C25H20O4	384.4	C1=CC=C2C(=C1)C=CC=C2C(=O)C3=CC=C(C4=CC=CC=C43)OCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BVQ3B6	(2S)-N-(3-Tert-butyl-1,2-oxazol-5-yl)-1-(4-fluorophenyl)-5-oxopyrrolidine-2-carboxamide	Investigative	67953246	C18H20FN3O3	345.4	CC(C)(C)C1=NOC(=C1)NC(=O)[C@@H]2CCC(=O)N2C3=CC=C(C=C3)F	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BX04OV	8-(2-Chlorophenyl)-2-Methyl-6-(4-Methylpiperazin-1-yl)-9-(tetrahydro-2H-pyran-4-yl)-9H-purine (hydrochloride)	Investigative	68604012	C22H28Cl2N6O	463.4	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C4CCOCC4)C5=CC=CC=C5Cl.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BX57JP	8-(2-Chloro-phenyl)-2-methyl-6-(4-methyl-piperazin-1-yl)-9-(tetrahydro-pyran-4-yl)-9h-purine	Investigative	46833780	C22H27ClN6O	426.9	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C4CCOCC4)C5=CC=CC=C5Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BY15MO	(E)-2-(Benzenesulfonyl)-3-[1-(2-piperidin-1-ylethyl)indol-3-yl]prop-2-enenitrile	Investigative	54577602	C24H25N3O2S	419.5	C1CCN(CC1)CCN2C=C(C3=CC=CC=C32)/C=C(\\C#N)/S(=O)(=O)C4=CC=CC=C4	Ki = 163400 nM	Poor binder
T76685	Cannabinoid receptor 1	BYP36K	(2S)-N-(6-Chloro-1H-benzimidazol-2-yl)-1-(oxan-4-yl)pyrrolidine-2-carboxamide	Investigative	67953333	C17H21ClN4O2	348.8	C1C[C@H](N(C1)C2CCOCC2)C(=O)NC3=NC4=C(N3)C=C(C=C4)Cl	EC50 ~ 50000 nM	Poor binder
T76685	Cannabinoid receptor 1	BZKT49	8-(2-Cyclopropylphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)purine;hydrochloride	Investigative	68604144	C25H33ClN6O	469	CC1=NC2=C(C(=N1)N3CCN(CC3)C)N=C(N2C4CCOCC4)C5=CC=CC=C5C6CC6.Cl	EC50 ~ 100000 nM	Poor binder
T76685	Cannabinoid receptor 1	BZM5Y8	8-(4-Methoxy-2-methylphenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(oxan-4-yl)purine;hydrochloride	Investigative	71762083	C24H33ClN6O2	473	CC1=C(C=CC(=C1)OC)C2=NC3=C(N2C4CCOCC4)N=C(N=C3N5CCN(CC5)C)C.Cl	EC50 ~ 100000 nM	Poor binder