TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T77350	Proteasome beta-8	B3QX7V	Chembl4129702	Investigative	145962247	C31H46FN5O5S	619.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1)CN)CS(=O)(=O)F)NC(=O)[C@H](CC2=CC=CC=C2)N	IC50 = 136500 nM	Poor binder
T77350	Proteasome beta-8	B92BLZ	Chembl4128074	Investigative	145960456	C27H46FN7O5S	599.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)CS(=O)(=O)F)NC(=O)[C@H](CC1=CC=CC=C1)N	IC50 ~ 100000 nM	Poor binder
T77350	Proteasome beta-8	BIR46C	(2S)-N-[(2S)-3-(1-Adamantyl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide	Investigative	118709573	C35H50N4O7	638.8	C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)OC)C(=O)N[C@@H](CC23CC4CC(C2)CC(C4)C3)C(=O)[C@]5(CO5)C)NC(=O)CN6CCOCC6	IC50 ~ 50000 nM	Poor binder
T77350	Proteasome beta-8	BO45XH	Chembl4127967	Investigative	145963426	C27H46FN5O5S	571.8	CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)CS(=O)(=O)F)NC(=O)[C@H](CC1=CC=CC=C1)N	IC50 ~ 100000 nM	Poor binder