TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T78932	TYK2 tyrosine kinase	B0NZT4	4-Chloro-N-(3-quinoxalin-2-ylphenyl)butanamide	Investigative	46917073	C18H16ClN3O	325.8	C1=CC=C2C(=C1)N=CC(=N2)C3=CC(=CC=C3)NC(=O)CCCCl	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	B18GAM	2-(Dimethylamino)-N-(3-quinoxalin-2-ylphenyl)acetamide	Investigative	46917070	C18H18N4O	306.4	CN(C)CC(=O)NC1=CC=CC(=C1)C2=NC3=CC=CC=C3N=C2	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	B1NM0O	3-Chloro-N-(3-quinoxalin-2-ylphenyl)propanamide	Investigative	46916410	C17H14ClN3O	311.8	C1=CC=C2C(=C1)N=CC(=N2)C3=CC(=CC=C3)NC(=O)CCCl	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	B28CHV	N-[3-(2-Quinoxalinyl)phenyl]methanesulfonamide	Investigative	1485426	C15H13N3O2S	299.3	CS(=O)(=O)NC1=CC=CC(=C1)C2=NC3=CC=CC=C3N=C2	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	B2X6MP	N-(3-Quinoxalin-2-ylphenyl)-2-(1,2,4-triazol-1-yl)acetamide	Investigative	46917074	C18H14N6O	330.3	C1=CC=C2C(=C1)N=CC(=N2)C3=CC(=CC=C3)NC(=O)CN4C=NC=N4	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	B4K3YE	N-[3-(2-Quinoxalinyl)phenyl]-2-furamide	Investigative	1485419	C19H13N3O2	315.3	C1=CC=C2C(=C1)N=CC(=N2)C3=CC(=CC=C3)NC(=O)C4=CC=CO4	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	B5QA4G	Chembl4285755	Investigative	145993080	C18H20N6O	336.4	CC1=CC(=CC(=C1)NC2=NN3C(=CN=C3C(=C2)NC4CC4)C(=O)N)C	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	B7LQ4K	2-(4-Methylpiperazin-1-yl)-N-(3-quinoxalin-2-ylphenyl)acetamide	Investigative	46916408	C21H23N5O	361.4	CN1CCN(CC1)CC(=O)NC2=CC=CC(=C2)C3=NC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BB5A6N	N-[4-(2-Quinoxalinyl)phenyl]cyclopropanecarboxamide	Investigative	45588498	C18H15N3O	289.3	C1CC1C(=O)NC2=CC=CC(=C2)C3=NC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BC34WF	N-Methyl-N'-[3-(2-quinoxalinyl)phenyl]thiourea	Investigative	1485416	C16H14N4S	294.4	CNC(=S)NC1=CC=CC(=C1)C2=NC3=CC=CC=C3N=C2	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BCVE73	N-[3-(2-Quinoxalinyl)phenyl]-2-thiophenesulfonamide	Investigative	1485420	C18H13N3O2S2	367.4	C1=CC=C2C(=C1)N=CC(=N2)C3=CC(=CC=C3)NS(=O)(=O)C4=CC=CS4	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BMJZ59	2-Morpholino-N-(3-(quinoxalin-2-yl)phenyl)acetamide	Investigative	46916411	C20H20N4O2	348.4	C1COCCN1CC(=O)NC2=CC=CC(=C2)C3=NC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BPD53O	Chembl4289149	Investigative	145987719	C18H14F3N7O	401.3	C1CC1NC2=CC(=NN3C2=NC=C3C(=O)N)NC4=CC(=CC(=C4)C(F)(F)F)C#N	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BRQ36B	2-Chloro-N-(3-quinoxalin-2-ylphenyl)propanamide	Investigative	58200382	C17H14ClN3O	311.8	CC(C(=O)NC1=CC=CC(=C1)C2=NC3=CC=CC=C3N=C2)Cl	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BSH4V3	N-(3-Quinoxalin-2-ylphenyl)propanamide	Investigative	952076	C17H15N3O	277.32	CCC(=O)NC1=CC=CC(=C1)C2=NC3=CC=CC=C3N=C2	IC50 ~ 50000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BUC3S5	N-(2-Methoxy-4-morpholinophenyl)-N'-cyclohexyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine	Investigative	121320416	C23H30N6O2	422.5	COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC4=C(C=CN4)C(=N3)NC5CCCCC5	IC50 = 132000 nM	Poor binder
T78932	TYK2 tyrosine kinase	BWV26C	N-(4-Methoxyphenyl)-N'-[3-(2-quinoxalinyl)phenyl]urea	Investigative	1485415	C22H18N4O2	370.4	COC1=CC=C(C=C1)NC(=O)NC2=CC=CC(=C2)C3=NC4=CC=CC=C4N=C3	IC50 ~ 50000 nM	Poor binder