TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T81850	Squalene synthetase	D0K8DI	SQ-109	Phase 2	5274428	C22H38N2	330.5	CC(=CCC/C(=C/CNCCNC1C2CC3CC(C2)CC1C3)/C)C	IC50 = 100000 nM	Poor binder
T81850	Squalene synthetase	BBL10Z	{[(4,6-Dimethylpyridin-2-yl)amino]methanediyl}bis(phosphonic acid)	Investigative	406073	C8H14N2O6P2	296.15	CC1=CC(=NC(=C1)NC(P(=O)(O)O)P(=O)(O)O)C	IC50 ~ 100000 nM	Poor binder
T81850	Squalene synthetase	BD92FI	(2E)-N-[2-(2-Adamantyloxy)ethyl]-3,7-dimethyl-2,6-octadiene-1-amine	Investigative	90655951	C22H37NO	331.5	CC(=CCC/C(=C/CNCCOC1C2CC3CC(C2)CC1C3)/C)C	IC50 = 100000 nM	Poor binder
T81850	Squalene synthetase	BI0RB7	N-[2-[(2E)-3,7-Dimethylocta-2,6-dienoxy]ethyl]adamantan-2-amine	Investigative	90655952	C22H37NO	331.5	CC(=CCC/C(=C/COCCNC1C2CC3CC(C2)CC1C3)/C)C	IC50 = 100000 nM	Poor binder
T81850	Squalene synthetase	BL0OW8	[[(6-Chloropyridin-3-yl)amino]-phosphonomethyl]phosphonic acid	Investigative	406065	C6H9ClN2O6P2	302.54	C1=CC(=NC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder