TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T82028	Sodium/hydrogen exchanger 1	D0I0RJ	Amiloride	Approved	16231	C6H8ClN7O	229.63	C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N	IC50 = 60000 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B0NTU9	1-Benzoyl-1H-benzotriazole	Investigative	570059	C13H9N3O	223.23	C1=CC=C(C=C1)C(=O)N2C3=CC=CC=C3N=N2	IC50 = 51570 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B0W5ZJ	1-(Phenylsulfonyl)-1H-benzotriazole	Investigative	750248	C12H9N3O2S	259.29	C1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3N=N2	IC50 = 50890 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B27IDV	2-Methylbenzotriazole	Investigative	85498	C7H7N3	133.15	CN1N=C2C=CC=CC2=N1	IC50 = 177000 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B3AU4J	2-Propylbenzotriazole	Investigative	4311536	C9H11N3	161.2	CCCN1N=C2C=CC=CC2=N1	IC50 = 135000 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B47CIG	1-Ethylbenzotriazole	Investigative	27939	C8H9N3	147.18	CCN1C2=CC=CC=C2N=N1	IC50 = 86480 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B70FYN	1-Methylbenzotriazole	Investigative	25902	C7H7N3	133.15	CN1C2=CC=CC=C2N=N1	IC50 = 97100 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B7SKJ4	1-Propylbenzotriazole	Investigative	3754503	C9H11N3	161.2	CCCN1C2=CC=CC=C2N=N1	IC50 = 72380 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	B7W0AB	1-Butyl-1H-benzo[d][1,2,3]triazole	Investigative	4401906	C10H13N3	175.23	CCCCN1C2=CC=CC=C2N=N1	IC50 = 68110 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BA9U6Z	2-Heptylbenzotriazole	Investigative	3789956	C13H19N3	217.31	CCCCCCCN1N=C2C=CC=CC2=N1	IC50 = 156540 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BGM95R	2-(3-Chloropropyl)benzotriazole	Investigative	3477267	C9H10ClN3	195.65	C1=CC2=NN(N=C2C=C1)CCCCl	IC50 = 115250 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BH14BI	1-Hexylbenzotriazole	Investigative	4202453	C12H17N3	203.28	CCCCCCN1C2=CC=CC=C2N=N1	IC50 = 60590 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BK3QL8	1-[(2,4-Dichlorophenyl)methyl]benzotriazole	Investigative	594606	C13H9Cl2N3	278.13	C1=CC=C2C(=C1)N=NN2CC3=C(C=C(C=C3)Cl)Cl	IC50 = 65140 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BKF6H1	(3R)-1-[(1S,2S)-4,6-Dichloro-1-[4-(3,5-dimethyl-1,2,4-triazol-4-yl)-2-fluorophenoxy]-2,3-dihydro-1H-inden-2-yl]pyrrolidin-3-ol;hydrochloride	Investigative	134137115	C23H24Cl3FN4O2	513.799	CC1=NN=C(N1C2=CC(=C(C=C2)O[C@@H]3[C@H](CC4=C3C=C(C=C4Cl)Cl)N5CC[C@H](C5)O)F)C.Cl	IC50 ~ 100000 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BN73WR	2-Hexylbenzotriazole	Investigative	3797398	C12H17N3	203.28	CCCCCCN1N=C2C=CC=CC2=N1	IC50 = 154670 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BNVJ06	1-(3-Chloropropyl)-1H-1,2,3-benzotriazole	Investigative	5243938	C9H10ClN3	195.65	C1=CC=C2C(=C1)N=NN2CCCCl	IC50 = 69750 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BPX73H	1H-Benzotriazole	Investigative	7220	C6H5N3	119.12	C1=CC2=NNN=C2C=C1	IC50 = 192680 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BR3NL1	2-Pentyl-2H-benzotriazole	Investigative	5244322	C11H15N3	189.26	CCCCCN1N=C2C=CC=CC2=N1	IC50 = 191230 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BR5NT9	1-Heptyl-1H-1,2,3-benzotriazole	Investigative	4359223	C13H19N3	217.31	CCCCCCCN1C2=CC=CC=C2N=N1	IC50 = 59230 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BX25LF	1-Benzyl-1H-benzotriazole	Investigative	521212	C13H11N3	209.25	C1=CC=C(C=C1)CN2C3=CC=CC=C3N=N2	IC50 = 72510 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BYIE30	1-Pentyl-1H-1,2,3-benzotriazole	Investigative	3708772	C11H15N3	189.26	CCCCCN1C2=CC=CC=C2N=N1	IC50 = 63470 nM	Poor binder
T82028	Sodium/hydrogen exchanger 1	BZ4RJ6	2-Butyl-2H-benzo[d][1,2,3]triazole	Investigative	3343351	C10H13N3	175.23	CCCCN1N=C2C=CC=CC2=N1	IC50 = 101120 nM	Poor binder