TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T84160 5-HT 3 receptor D0T8GD Nicotine Approved 89594 C10H14N2 162.23 CN1CCC[C@H]1C2=CN=CC=C2 Ki = 71000 nM Poor binder T84160 5-HT 3 receptor B2N4BO 7-Methoxy-4-[4-(4-pyrazol-1-ylbutyl)piperazin-1-yl]pyrrolo[1,2-a]quinoxaline Investigative 44296810 C23H28N6O 404.5 COC1=CC2=C(C=C1)N3C=CC=C3C(=N2)N4CCN(CC4)CCCCN5C=CC=N5 IC50 ~ 100000 nM Poor binder T84160 5-HT 3 receptor BSM3N9 7-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-10-methyl-2,8,13-triazatricyclo[7.4.0.02,6]trideca-1(13),3,5,7,9,11-hexaene Investigative 10714509 C22H22FN5 375.4 CC1=C2C(=NC=C1)N3C=CC=C3C(=N2)N4CCN(CC4)CC5=CC=C(C=C5)F IC50 ~ 100000 nM Poor binder