TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T85309	Cystathionine beta-synthase	B0NS2W	5-Benzylidene-2-thiohydantoin	Investigative	1396823	C10H8N2OS	204.25	C1=CC=C(C=C1)/C=C\\2/C(=O)NC(=S)N2	IC50 = 170000 nM	Poor binder
T85309	Cystathionine beta-synthase	B2FIO8	2-Thioxo-5-[(Z)-3-methoxy-4-acetoxybenzylidene]imidazolidine-4-one	Investigative	21604873	C13H12N2O4S	292.31	CC(=O)OC1=C(C=C(C=C1)/C=C\\2/C(=O)NC(=S)N2)OC	IC50 = 83000 nM	Poor binder
T85309	Cystathionine beta-synthase	B4QA9O	(5Z)-5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one	Investigative	2246840	C11H10N2O3S	250.28	COC1=C(C=CC(=C1)/C=C\\2/C(=O)NC(=S)N2)O	IC50 = 187000 nM	Poor binder
T85309	Cystathionine beta-synthase	B74SEI	(5Z)-5-[(3,4-Dihydroxyphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one	Investigative	7032560	C10H8N2O3S	236.25	C1=CC(=C(C=C1/C=C\\2/C(=O)NC(=S)N2)O)O	IC50 = 125000 nM	Poor binder
T85309	Cystathionine beta-synthase	BBW36C	(5Z)-5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-3-methyl-2-methylsulfanylimidazol-4-one	Investigative	118729943	C13H14N2O3S	278.33	CN1C(=O)/C(=C/C2=CC(=C(C=C2)O)OC)/N=C1SC	IC50 = 87000 nM	Poor binder
T85309	Cystathionine beta-synthase	BGK4T6	Rubrolide A	Investigative	6055630	C17H8Br4O4	595.9	C1=C(C=C(C(=C1Br)O)Br)/C=C\\2/C(=CC(=O)O2)C3=CC(=C(C(=C3)Br)O)Br	IC50 = 108000 nM	Poor binder
T85309	Cystathionine beta-synthase	BSE0G5	Sodium;[(1S)-1-methyl-12,17-dioxo-14-oxapentacyclo[11.6.1.02,11.04,9.016,20]icosa-2(11),3,5,7,9,13(20),15-heptaen-5-yl] sulfate	Investigative	118729944	C20H13NaO7S	420.4	C[C@@]12CCC(=O)C3=COC(=C31)C(=O)C4=C2C=C5C(=C4)C=CC=C5OS(=O)(=O)[O-].[Na+]	IC50 = 136000 nM	Poor binder
T85309	Cystathionine beta-synthase	D0I4NN	4,5-Dibromo-1H-pyrrole-2-carboxylic acid amide	Investigative	14056555	C5H4Br2N2O	267.91	C1=C(NC(=C1Br)Br)C(=O)N	IC50 = 156000 nM	Poor binder