TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T85540	Lysine-specific demethylase 5C	B0Z5XV	Tcmdc-142577	Investigative	22581449	C17H15N3O3S2	373.5	CCS(=O)(=O)C1=CC=C(C=C1)C(=O)NC2=NC(=CS2)C3=CC=CC=N3	IC50 = 52800 nM	Poor binder
T85540	Lysine-specific demethylase 5C	B1S4EU	8-[(4-Phenylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-one	Investigative	137175087	C18H19N5O	321.4	C1CN(CCN1CC2=NC=CC3=C2N=CNC3=O)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	B25OJN	3-{[(Furan-2-yl)methyl]amino}pyridine-4-carboxylic acid	Investigative	81750201	C11H10N2O3	218.21	C1=COC(=C1)CNC2=C(C=CN=C2)C(=O)O	IC50 = 63095.73 nM	Poor binder
T85540	Lysine-specific demethylase 5C	B3JMD0	8-(Piperidin-1-ylmethyl)-3H-pyrido[3,4-d]pyrimidin-4-one	Investigative	137175225	C13H16N4O	244.29	C1CCN(CC1)CC2=NC=CC3=C2N=CNC3=O	IC50 = 111000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	B83GMK	2-(6-Propan-2-ylpyridin-3-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-one	Investigative	136053683	C15H14N4O2	282.3	CC(C)C1=NC=C(C=C1)OC2=NC3=C(C=CN=C3)C(=O)N2	IC50 = 50118.72 nM	Poor binder
T85540	Lysine-specific demethylase 5C	B9JXS6	8-(1-Methylpyrazol-3-yl)-3H-pyrido[3,4-d]pyrimidin-4-one	Investigative	137175084	C11H9N5O	227.22	CN1C=CC(=N1)C2=NC=CC3=C2N=CNC3=O	IC50 = 103400 nM	Poor binder
T85540	Lysine-specific demethylase 5C	B9PNO0	4-(Isopropylamino)-4-oxobutanoic acid	Investigative	245007	C7H13NO3	159.18	CC(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	B9UVL8	2-[(2-Furylmethyl)amino]nicotinic acid	Investigative	28330466	C11H10N2O3	218.21	C1=CC(=C(N=C1)NCC2=CC=CO2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BB3XA1	5-Chloro-7-[benzoylamino(3-methyl-2-thienyl)methyl]-8-quinolinol	Investigative	122383780	C22H17ClN2O2S	408.9	CC1=C(SC=C1)C(C2=CC(=C3C=CC=NC3=C2O)Cl)NC(=O)C4=CC=CC=C4	IC50 = 178000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BBPZ30	3-(Methylsulfonyl)-N-(4-(pyridin-2-yl)thiazol-2-yl)benzamide	Investigative	22581416	C16H13N3O3S2	359.4	CS(=O)(=O)C1=CC=CC(=C1)C(=O)NC2=NC(=CS2)C3=CC=CC=N3	IC50 = 71900 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BDI7W1	2-(1-Benzylpyrazol-4-yl)oxy-3H-pyrido[2,3-d]pyrimidin-4-one	Investigative	136644692	C17H13N5O2	319.32	C1=CC=C(C=C1)CN2C=C(C=N2)OC3=NC4=C(C=CC=N4)C(=O)N3	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BIXF84	(3-Carboxypropanoylamino)-trimethylazanium	Investigative	71453382	C7H15N2O3+	175.21	C[N+](C)(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BN86AV	N'1,N'1,N'4,N'4-Tetramethylsuccinohydrazide	Investigative	2238068	C8H18N4O2	202.25	CN(C)NC(=O)CCC(=O)NN(C)C	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BT3E7X	2-[(3-Methylthiophen-2-yl)methylamino]pyridine-3-carboxylic acid	Investigative	112726150	C12H12N2O2S	248.3	CC1=C(SC=C1)CNC2=C(C=CC=N2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BTWI25	8-[(4-Pyridin-2-ylpiperazin-1-yl)methyl]-3H-pyrido[3,4-d]pyrimidin-4-one	Investigative	137175088	C17H18N6O	322.4	C1CN(CCN1CC2=NC=CC3=C2N=CNC3=O)C4=CC=CC=N4	IC50 = 88000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BVE23M	4-[Dimethylamino(methyl)amino]-4-oxobutanoic acid	Investigative	71451542	C7H14N2O3	174.2	CN(C)N(C)C(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BVPH69	5-Quinolinecarboxylic acid, 8-hydroxy-, octyl ester	Investigative	125377518	C18H23NO3	301.4	CCCCCCCCOC(=O)C1=C2C=CC=NC2=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	BW3UN6	Tranylcypromine hydrochloride	Investigative	2723716	C9H12ClN	169.65	C1[C@H]([C@@H]1N)C2=CC=CC=C2.Cl	IC50 ~ 100000 nM	Poor binder
T85540	Lysine-specific demethylase 5C	D0B2WZ	daminozide	Investigative	15331	C6H12N2O3	160.17	CN(C)NC(=O)CCC(=O)O	IC50 ~ 100000 nM	Poor binder