TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T87588	Glutamate receptor ionotropic kainate 4	B3T4OA	2-Amino-3-[3-hydroxy-5-(1-methyl-1H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid	Investigative	10658567	C8H10N6O4	254.2	CN1C(=NN=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	B7S9JZ	(3s,4Ar,6r,8ar)-6-(2h-tetrazol-5-yl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	Investigative	10538709	C11H17N5O2	251.29	C1C[C@H]2CN[C@@H](C[C@H]2C[C@@H]1C3=NNN=N3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	B9F7YG	(3s,4Ar,6s,8ar)-6-(2h-tetrazol-5-ylmethyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	Investigative	10084218	C12H19N5O2	265.31	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1CC3=NNN=N3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	BALN60	6,7-Dichloro-N-methylsulfonyl-3-oxo-4H-quinoxaline-2-carboxamide	Investigative	44379376	C10H7Cl2N3O4S	336.15	CS(=O)(=O)NC(=O)C1=NC2=CC(=C(C=C2NC1=O)Cl)Cl	IC50 = 103000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	BGN92D	(3s,4Ar,6s,8ar)-6-(2h-tetrazol-5-yl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxylic acid	Investigative	9837860	C11H17N5O2	251.29	C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1C3=NNN=N3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	BMH0S9	2-Amino-3-[3-oxo-5-(2H-tetrazol-5-yl)-1,2-oxazol-4-yl]propanoic Acid	Investigative	10800053	C7H8N6O4	240.18	C(C1=C(ONC1=O)C2=NNN=N2)C(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	BMI8G9	2-Amino-3-[3-oxo-5-(1H-1,2,4-triazol-5-yl)-1,2-oxazol-4-yl]propanoic acid	Investigative	10752476	C8H9N5O4	239.19	C1=NNC(=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 = 58000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	BORD40	2-Amino-3-[5-(1-methyl-1,2,4-triazol-3-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10824747	C9H11N5O4	253.22	CN1C=NC(=N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	BP58CG	2-Amino-3-[5-(1H-imidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10823814	C9H10N4O4	238.2	C1=CN=C(N1)C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	BU27PT	2-Amino-3-[5-(1-methylimidazol-2-yl)-3-oxo-1,2-oxazol-4-yl]propanoic acid	Investigative	10610792	C10H12N4O4	252.23	CN1C=CN=C1C2=C(C(=O)NO2)CC(C(=O)O)N	IC50 = 74000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	D03RGP	(R,S)-AMPA	Investigative	1221	C7H10N2O4	186.17	CC1=C(C(=O)NO1)CC(C(=O)O)N	IC50 = 68000 nM	Poor binder
T87588	Glutamate receptor ionotropic kainate 4	D04DHB	5,7-Dichlorokynurenic Acid	Investigative	1779	C10H5Cl2NO3	258.05	C1=C(C=C(C2=C1NC(=CC2=O)C(=O)O)Cl)Cl	IC50 ~ 100000 nM	Poor binder